O94888: UBX domain-containing protein 7

General Information

Protein names	- UBX domain-containing protein 7
Gene names	UBXN7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O94888

12 N-termini

5 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAHGGSAAS SALKGLIQQF TTITGASESV GKHMLEACNN NLEMAVTMFL DGGGIAEEPS
        70         80         90        100        110        120
TSSASVSTVR PHTEEEVRAP IPQKQEILVE PEPLFGAPKR RRPARSIFDG FRDFQTETIR
       130        140        150        160        170        180
QEQELRNGGA IDKKLTTLAD LFRPPIDLMH KGSFETAKEC GQMQNKWLMI NIQNVQDFAC
       190        200        210        220        230        240
QCLNRDVWSN EAVKNIIREH FIFWQVYHDS EEGQRYIQFY KLGDFPYVSI LDPRTGQKLV
       250        260        270        280        290        300
EWHQLDVSSF LDQVTGFLGE HGQLDGLSSS PPKKCARSES LIDASEDSQL EAAIRASLQE
       310        320        330        340        350        360
THFDSTQTKQ DSRSDEESES ELFSGSEEFI SVCGSDEEEE VENLAKSRKS PHKDLGHRKE
       370        380        390        400        410        420
ENRRPLTEPP VRTDPGTATN HQGLPAVDSE ILEMPPEKAD GVVEGIDVNG PKAQLMLRYP
       430        440        450        460        470        480
DGKREQITLP EQAKLLALVK HVQSKGYPNE RFELLTNFPR RKLSHLDYDI TLQEAGLCPQ

ETVFVQERN

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

12 N-termini - 5 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O94888-2-unknown	MAAHGG...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O94888-2-Acetylation	AAHGGS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O94888-34-unknown	MLEACN...	34		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000404778
O94888-52-	GGGIAE...	52			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O94888-110-	GFRDFQ...	110			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
O94888-110-	GFRDFQ...	110			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O94888-110-	GFRDFQ...	110			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O94888-110-unknown	GFRDFQ...	110			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O94888-149-unknown	MHKGSF...	149		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000440716
O94888-163-unknown	MQNKWL...	163		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000397256
O94888-288-unknown	SQLEAA...	288		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10990
O94888-300-unknown	ETHFDS...	300		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7074
O94888-401-	GVVEGI...	401			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
O94888-401-	GVVEGI...	401			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
O94888-401-	GVVEGI...	401			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O94888-401-	GVVEGI...	401			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O94888-401-	GVVEGI...	401			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
O94888-401-	GVVEGI...	401			Subtiligase Based Positive Selection		Wells	RMPI_untreated	23264352
O94888-401-unknown	GVVEGI...	401			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RSIFDG	109	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000404778
...RPPIDL	147	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000371311
...DASEDS	287	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10990
...RASLQE	299	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7074
...VQERN	489	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	287	SEDS.\|.SQLE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
CATS_HUMAN	299	SLQE.\|.ETHF	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)