Q16186: Proteasomal ubiquitin receptor ADRM1

General Information

Protein names	- Proteasomal ubiquitin receptor ADRM1 - 110 kDa cell membrane glycoprotein - Gp110 - Adhesion-regulating molecule 1 - ARM-1 - Proteasome regulatory particle non-ATPase 13 - hRpn13 - Rpn13 homolog
Gene names	ADRM1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q16186

9 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTTSGALFPS LVPGSRGASN KYLVEFRAGK MSLKGTTVTP DKRKGLVYIQ QTDDSLIHFC
        70         80         90        100        110        120
WKDRTSGNVE DDLIIFPDDC EFKRVPQCPS GRVYVLKFKA GSKRLFFWMQ EPKTDQDEEH
       130        140        150        160        170        180
CRKVNEYLNN PPMPGALGAS GSSGHELSAL GGEGGLQSLL GNMSHSQLMQ LIGPAGLGGL
       190        200        210        220        230        240
GGLGALTGPG LASLLGSSGP PGSSSSSSSR SQSAAVTPSS TTSSTRATPA PSAPAAASAT
       250        260        270        280        290        300
SPSPAPSSGN GASTAASPTQ PIQLSDLQSI LATMNVPAGP AGGQQVDLAS VLTPEIMAPI
       310        320        330        340        350        360
LANADVQERL LPYLPSGESL PQTADEIQNT LTSPQFQQAL GMFSAALASG QLGPLMCQFG
       370        380        390        400
LPAEAVEAAN KGDVEAFAKA MQNNAKPEQK EGDTKDKKDE EEDMSLD

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

9 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q16186-2-unknown	MTTSGA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q16186-2-Acetylation	TTSGAL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q16186-2-Acetylation	TTSGAL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q16186-2-Acetylation	TTSGAL...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q16186-92-unknown	RVYVLK...	92		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q16186-177-unknown	LGGLGG...	177		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4116
Q16186-197-	SSGPPG...	197			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q16186-197-	SSGPPG...	197			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q16186-211-	SQSAAV...	211			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q16186-213-	SAAVTP...	213			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q16186-215-	AVTPSS...	215			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q16186-368-unknown	AANKGD...	368		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7872

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IGPAGL	176	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4116
...AEAVEA	367	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7872
...DMSLD	407	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	176	PAGL.\|.LGGL	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	367	AVEA.\|.AANK	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)