Q96CW5: Gamma-tubulin complex component 3

General Information

Protein names	- Gamma-tubulin complex component 3 - GCP-3 - hGCP3 - Gamma-ring complex protein 104 kDa - h104p - hGrip104 - Spindle pole body protein Spc98 homolog - hSpc98
Gene names	TUBGCP3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96CW5

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Gamma-tubulin complex component 3 - Isoform 3 of Gamma-tubulin complex component 3

Sequence View

        10         20         30         40         50         60
MATPDQKSPN VLLQNLCCRI LGRSEADVAQ QFQYAVRVIG SNFAPTVERD EFLVAEKIKK
        70         80         90        100        110        120
ELIRQRREAD AALFSELHRK LHSQGVLKNK WSILYLLLSL SEDPRRQPSK VSSYATLFAQ
       130        140        150        160        170        180
ALPRDAHSTP YYYARPQTLP LSYQDRSAQS AQSSGSVGSS GISSIGLCAL SGPAPAPQSL
       190        200        210        220        230        240
LPGQSNQAPG VGDCLRQQLG SRLAWTLTAN QPSSQATTSK GVPSAVSRNM TRSRREGDTG
       250        260        270        280        290        300
GTMEITEAAL VRDILYVFQG IDGKNIKMNN TENCYKVEGK ANLSRSLRDT AVRLSELGWL
       310        320        330        340        350        360
HNKIRRYTDQ RSLDRSFGLV GQSFCAALHQ ELREYYRLLS VLHSQLQLED DQGVNLGLES
       370        380        390        400        410        420
SLTLRRLLVW TYDPKIRLKT LAALVDHCQG RKGGELASAV HAYTKTGDPY MRSLVQHILS
       430        440        450        460        470        480
LVSHPVLSFL YRWIYDGELE DTYHEFFVAS DPTVKTDRLW HDKYTLRKSM IPSFMTMDQS
       490        500        510        520        530        540
RKVLLIGKSI NFLHQVCHDQ TPTTKMIAVT KSAESPQDAA DLFTDLENAF QGKIDAAYFE
       550        560        570        580        590        600
TSKYLLDVLN KKYSLLDHMQ AMRRYLLLGQ GDFIRHLMDL LKPELVRPAT TLYQHNLTGI
       610        620        630        640        650        660
LETAVRATNA QFDSPEILRR LDVRLLEVSP GDTGWDVFSL DYHVDGPIAT VFTRECMSHY
       670        680        690        700        710        720
LRVFNFLWRA KRMEYILTDI RKGHMCNAKL LRNMPEFSGV LHQCHILASE MVHFIHQMQY
       730        740        750        760        770        780
YITFEVLECS WDELWNKVQQ AQDLDHIIAA HEVFLDTIIS RCLLDSDSRA LLNQLRAVFD
       790        800        810        820        830        840
QIIELQNAQD AIYRAALEEL QRRLQFEEKK KQREIEGQWG VTAAEEEEEN KRIGEFKESI
       850        860        870        880        890        900
PKMCSQLRIL THFYQGIVQQ FLVLLTTSSD ESLRFLSFRL DFNEHYKARE PRLRVSLGTR

GRRSSHT         10         20         30         40         50         60
MATPDQKSPN VLLQNLCCRI LGRSEADVAQ QFQYAVRVIG SNFAPTVERD EFLVAEKIKK
        70         80         90        100        110        120
ELIRQRREAD AALFSELHRK LHSQGVLKNK WSILYLLLSL SEDPRRQPSK VSSYATLFAQ
       130        140        150        160        170        180
ALPRDAHSTP YYYARPQTLP LSYQDRSAQS AQSSGSVGSS GISSIGLCAL SGPAPAPQSL
       190        200        210        220        230        240
LPGQSNQAPG VGDCLRQQLG SRLAWTLTAN QPSSQATTSK GVPSAVSRNM TRSRREGDTG
       250        260        270        280        290        300
GTMEITEAAL VRDILYVFQG IDGKNIKMNN TENCYKVEGK ANLSRSLRDT AVRLSELGWL
       310        320        330        340        350        360
HNKIRRYTDQ RSLDRSFGLV GQSFCAALHQ ELREYYRLLS VLHSQLQLED DQGVNLGLES
       370        380        390        400        410        420
SLTLRRLLVW TYDPKIRLKT LAALVDHCQG RKGGELASAV HAYTKTGDPY MRSLVQHILS
       430        440        450        460        470        480
LVSHPVLSFL YRWIYDGELE DTYHEFFVAS DPTVKTDRLW HDKYTLRKSM IPSFMTMDQS
       490        500        510        520        530        540
RKVLLIGKSI NFLHQVCHDQ TPTTKMIAVT KSAESPQDAA DLFTDLENAF QGKIDAAYFE
       550        560        570        580        590        600
TSKYLLDVLN KKYSLLDHMQ AMRRYLLLGQ GDFIRHLMDL LKPELVRPAT TLYQHNLTGI
       610        620        630        640        650        660
LETAVRATNA QFDSPEILRR LDVRLLEVSP GDTGWDVFSL DYHVDGPIAT VFTRECMSHY
       670        680        690        700        710        720
LRVFNFLWRA KRMEYILTDI RKGHMCNAKL LRNMPEFSGV LHQCHILASE MVHFIHQMQY
       730        740        750        760        770        780
YITFEVLECS WDELWNKVQQ AQDLDHIIAA HEVFLDTIIS RCLLDSDSRA LLNQLRAVFD
       790        800        810        820        830        840
QIIELQNAQD AIYRAALEEL QRRLQFEEKK KQREIEGQWG VTAAEEEEEN KRIGEFKESI
       850        860        870        880        890        900
PKMCSQLRIL THFYQGIVQQ FLVLLTTSSD ESLRFLSFRL DFNEHYKARE PRLRVSLGTR

GRRSSHT

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96CW5-1-unknown	MATPDQ...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75795
Q96CW5-1-unknown	MATPDQ...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75796
Q96CW5-2-unknown	MATPDQ...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96CW5-2-Acetylation	ATPDQK...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96CW5-2-Acetylation	ATPDQK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q96CW5-2-Acetylation	ATPDQK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q96CW5-2-Acetylation	ATPDQK...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111658
Q96CW5-2-Acetylation	ATPDQK...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111659
Q96CW5-495-unknown	QVCHDQ...	495		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8010
Q96CW5-495-unknown	QVCHDQ...	495		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt153355

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...INFLHQ	494	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8010
...INFLHQ	494	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt136779
...RSSHT	907	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	494	FLHQ.\|.QVCH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)