Q8NDC0: MAPK-interacting and spindle-stabilizing protein-like

General Information

Protein names	- MAPK-interacting and spindle-stabilizing protein-like - Mitogen-activated protein kinase 1-interacting protein 1-like
Gene names	MAPK1IP1L
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8NDC0

5 N-termini

2 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSDEFSLADA LPEHSPAKTS AVSNTKPGQP PQGWPGSNPW NNPSAPSSVP SGLPPSATPS
        70         80         90        100        110        120
TVPFGPAPTG MYPSVPPTGP PPGPPAPFPP SGPSCPPPGG PYPAPTVPGP GPTGPYPTPN
       130        140        150        160        170        180
MPFPELPRPY GAPTDPAAAG PLGPWGSMSS GPWAPGMGGQ YPTPNMPYPS PGPYPAPPPP
       190        200        210        220        230        240
QAPGAAPPVP WGTVPPGAWG PPAPYPAPTG SYPTPGLYPT PSNPFQVPSG PSGAPPMPGG

PHSYH

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8NDC0-2-unknown	MSDEFS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8NDC0-2-Acetylation	SDEFSL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8NDC0-6-	SLADAL...	6			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q8NDC0-9-unknown	DALPEH...	9		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7959
Q8NDC0-9-unknown	DALPEH...	9		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6587
Q8NDC0-10-	ALPEHS...	10			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q8NDC0-10-	ALPEHS...	10			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q8NDC0-10-	ALPEHS...	10			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q8NDC0-10-	ALPEHS...	10			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q8NDC0-10-	ALPEHS...	10			Subtiligase Based Positive Selection		Wells	RMPI_untreated	23264352
Q8NDC0-10-	ALPEHS...	10			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EFSLAD	8	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7959
...EFSLAD	8	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6587
...PHSYH	245	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	8	SLAD.\|.DALP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	8	SLAD.\|.DALP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)