O60907: F-box-like/WD repeat-containing protein TBL1X

General Information

Protein names	- F-box-like/WD repeat-containing protein TBL1X - SMAP55 - Transducin beta-like protein 1X - Transducin-beta-like protein 1, X-linked
Gene names	TBL1X
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O60907

6 N-termini

2 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTELAGASSS CCHRPAGRGA MQSVLHHFQR LRGREGGSHF INTSSPRGEA KMSITSDEVN
        70         80         90        100        110        120
FLVYRYLQES GFSHSAFTFG IESHISQSNI NGTLVPPAAL ISILQKGLQY VEAEISINED
       130        140        150        160        170        180
GTVFDGRPIE SLSLIDAVMP DVVQTRQQAF REKLAQQQAS AAAAAAAATA AATAATTTSA
       190        200        210        220        230        240
GVSHQNPSKN REATVNGEEN RAHSVNNHAK PMEIDGEVEI PSSKATVLRG HESEVFICAW
       250        260        270        280        290        300
NPVSDLLASG SGDSTARIWN LNENSNGGST QLVLRHCIRE GGHDVPSNKD VTSLDWNTNG
       310        320        330        340        350        360
TLLATGSYDG FARIWTEDGN LASTLGQHKG PIFALKWNRK GNYILSAGVD KTTIIWDAHT
       370        380        390        400        410        420
GEAKQQFPFH SAPALDVDWQ NNTTFASCST DMCIHVCRLG CDRPVKTFQG HTNEVNAIKW
       430        440        450        460        470        480
DPSGMLLASC SDDMTLKIWS MKQEVCIHDL QAHNKEIYTI KWSPTGPATS NPNSNIMLAS
       490        500        510        520        530        540
ASFDSTVRLW DIERGVCTHT LTKHQEPVYS VAFSPDGKYL ASGSFDKCVH IWNTQSGNLV
       550        560        570
HSYRGTGGIF EVCWNARGDK VGASASDGSV CVLDLRK

Isoforms

- Isoform 2 of F-box-like/WD repeat-containing protein TBL1X

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O60907-1-unknown	MTELAG...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O60907-2-acetylation	TELAGA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O60907-2-acetylation	TELAGA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O60907-52-unknown	MSITSD...	52		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt91666
O60907-137-unknown	AVMPDV...	137		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165823
O60907-137-	AVMPDV...	137			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
O60907-137-	AVMPDV...	137			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O60907-410-unknown	GHTNEV...	410		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5217
O60907-410-unknown	GHTNEV...	410		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7057
O60907-410-unknown	GHTNEV...	410		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151135

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VKTFQG	409	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5217
...VKTFQG	409	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7057
...VKTFQG	409	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134537
...LDLRK	577	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LDLRK	577	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87284

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	409	TFQG.\|.GHTN	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	409	TFQG.\|.GHTN	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)