P15259: Phosphoglycerate mutase 2

General Information

Protein names	- Phosphoglycerate mutase 2 - 5.4.2.11 {ECO:0000250\|UniProtKB:P18669} - 5.4.2.4 {ECO:0000250\|UniProtKB:P18669} - BPG-dependent PGAM 2 - Muscle-specific phosphoglycerate mutase - Phosphoglycerate mutase isozyme M - PGAM-M
Gene names	PGAM2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P15259

4 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATHRLVMVR HGESTWNQEN RFCGWFDAEL SEKGTEEAKR GAKAIKDAKM EFDICYTSVL
        70         80         90        100        110        120
KRAIRTLWAI LDGTDQMWLP VVRTWRLNER HYGGLTGLNK AETAAKHGEE QVKIWRRSFD
       130        140        150        160        170        180
IPPPPMDEKH PYYNSISKER RYAGLKPGEL PTCESLKDTI ARALPFWNEE IVPQIKAGKR
       190        200        210        220        230        240
VLIAAHGNSL RGIVKHLEGM SDQAIMELNL PTGIPIVYEL NKELKPTKPM QFLGDEETVR
       250
KAMEAVAAQG KAK

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
P15259-1-unknown	MATHRL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P15259-94-unknown	GLTGLN...	94		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5617
P15259-208-acetylation	LNLPTG...	208	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P15259-232-unknown	FLGDEE...	232		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3654
P15259-232-unknown	FLGDEE...	232		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7342

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...ERHYGG	93	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5617
...TKPMQF	231	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3654
...TKPMQF	231	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7342
...QGKAK	253	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...QGKAK	253		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...QGKAK	253		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...QGKAK	253		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...QGKAK	253		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	93	HYGG.\|.GLTG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	231	PMQF.\|.FLGD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	231	PMQF.\|.FLGD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)