P56545: C-terminal-binding protein 2

General Information

Protein names	- C-terminal-binding protein 2 - CtBP2
Gene names	CTBP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P56545

3 N-termini

3 C-termini

4 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of C-terminal-binding protein 2 - Isoform 3 of C-terminal-binding protein 2

Sequence View

        10         20         30         40         50         60
MALVDKHKVK RQRLDRICEG IRPQIMNGPL HPRPLVALLD GRDCTVEMPI LKDLATVAFC
        70         80         90        100        110        120
DAQSTQEIHE KVLNEAVGAM MYHTITLTRE DLEKFKALRV IVRIGSGYDN VDIKAAGELG
       130        140        150        160        170        180
IAVCNIPSAA VEETADSTIC HILNLYRRNT WLYQALREGT RVQSVEQIRE VASGAARIRG
       190        200        210        220        230        240
ETLGLIGFGR TGQAVAVRAK AFGFSVIFYD PYLQDGIERS LGVQRVYTLQ DLLYQSDCVS
       250        260        270        280        290        300
LHCNLNEHNH HLINDFTIKQ MRQGAFLVNA ARGGLVDEKA LAQALKEGRI RGAALDVHES
       310        320        330        340        350        360
EPFSFAQGPL KDAPNLICTP HTAWYSEQAS LEMREAAATE IRRAITGRIP ESLRNCVNKE
       370        380        390        400        410        420
FFVTSAPWSV IDQQAIHPEL NGATYRYPPG IVGVAPGGLP AAMEGIIPGG IPVTHNLPTV
       430        440
AHPSQAPSPN QPTKHGDNRE HPNEQ         10         20         30         40         50         60
MALVDKHKVK RQRLDRICEG IRPQIMNGPL HPRPLVALLD GRDCTVEMPI LKDLATVAFC
        70         80         90        100        110        120
DAQSTQEIHE KVLNEAVGAM MYHTITLTRE DLEKFKALRV IVRIGSGYDN VDIKAAGELG
       130        140        150        160        170        180
IAVCNIPSAA VEETADSTIC HILNLYRRNT WLYQALREGT RVQSVEQIRE VASGAARIRG
       190        200        210        220        230        240
ETLGLIGFGR TGQAVAVRAK AFGFSVIFYD PYLQDGIERS LGVQRVYTLQ DLLYQSDCVS
       250        260        270        280        290        300
LHCNLNEHNH HLINDFTIKQ MRQGAFLVNA ARGGLVDEKA LAQALKEGRI RGAALDVHES
       310        320        330        340        350        360
EPFSFAQGPL KDAPNLICTP HTAWYSEQAS LEMREAAATE IRRAITGRIP ESLRNCVNKE
       370        380        390        400        410        420
FFVTSAPWSV IDQQAIHPEL NGATYRYPPG IVGVAPGGLP AAMEGIIPGG IPVTHNLPTV
       430        440
AHPSQAPSPN QPTKHGDNRE HPNEQ

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P56545-1-unknown	MALVDK...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P56545-61-unknown	DAQSTQ...	61	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6061
P56545-61-unknown	DAQSTQ...	61	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7597
P56545-61-unknown	DAQSTQ...	61	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt154599
P56545-422-unknown	HPSQAP...	422	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6063
P56545-422-unknown	HPSQAP...	422	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7599
P56545-422-unknown	HPSQAP...	422	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt157074

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TVAFCD	60	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6061
...TVAFCD	60	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7597
...TVAFCD	60	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt138023
...LPTVAH	421	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6063
...LPTVAH	421	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7599
...LPTVAH	421	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140572
...HPNEQ	445	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...HPNEQ	445	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67595

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	60	AFCD.\|.DAQS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	60	AFCD.\|.DAQS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	421	TVAH.\|.HPSQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	421	TVAH.\|.HPSQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)