Q9NVS9: Pyridoxine-5'-phosphate oxidase

General Information

Protein names	- Pyridoxine-5'-phosphate oxidase - 1.4.3.5 - Pyridoxamine-phosphate oxidase
Gene names	PNPO
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NVS9

8 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Pyridoxine-5'-phosphate oxidase - Isoform 3 of Pyridoxine-5'-phosphate oxidase - Isoform 4 of Pyridoxine-5'-phosphate oxidase

Sequence View

        10         20         30         40         50         60
MTCWLRGVTA TFGRPAEWPG YLSHLCGRSA AMDLGPMRKS YRGDREAFEE THLTSLDPVK
        70         80         90        100        110        120
QFAAWFEEAV QCPDIGEANA MCLATCTRDG KPSARMLLLK GFGKDGFRFF TNFESRKGKE
       130        140        150        160        170        180
LDSNPFASLV FYWEPLNRQV RVEGPVKKLP EEEAECYFHS RPKSSQIGAV VSHQSSVIPD
       190        200        210        220        230        240
REYLRKKNEE LEQLYQDQEV PKPKSWGGYV LYPQVMEFWQ GQTNRLHDRI VFRRGLPTGD
       250        260
SPLGPMTHRG EEDWLYERLA P         10         20         30         40         50         60
MTCWLRGVTA TFGRPAEWPG YLSHLCGRSA AMDLGPMRKS YRGDREAFEE THLTSLDPVK
        70         80         90        100        110        120
QFAAWFEEAV QCPDIGEANA MCLATCTRDG KPSARMLLLK GFGKDGFRFF TNFESRKGKE
       130        140        150        160        170        180
LDSNPFASLV FYWEPLNRQV RVEGPVKKLP EEEAECYFHS RPKSSQIGAV VSHQSSVIPD
       190        200        210        220        230        240
REYLRKKNEE LEQLYQDQEV PKPKSWGGYV LYPQVMEFWQ GQTNRLHDRI VFRRGLPTGD
       250        260
SPLGPMTHRG EEDWLYERLA P         10         20         30         40         50         60
MTCWLRGVTA TFGRPAEWPG YLSHLCGRSA AMDLGPMRKS YRGDREAFEE THLTSLDPVK
        70         80         90        100        110        120
QFAAWFEEAV QCPDIGEANA MCLATCTRDG KPSARMLLLK GFGKDGFRFF TNFESRKGKE
       130        140        150        160        170        180
LDSNPFASLV FYWEPLNRQV RVEGPVKKLP EEEAECYFHS RPKSSQIGAV VSHQSSVIPD
       190        200        210        220        230        240
REYLRKKNEE LEQLYQDQEV PKPKSWGGYV LYPQVMEFWQ GQTNRLHDRI VFRRGLPTGD
       250        260
SPLGPMTHRG EEDWLYERLA P

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

8 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NVS9-1-unknown	MTCWLR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NVS9-30-unknown	AAMDLG...	30		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9NVS9-30-	AAMDLG...	30		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9NVS9-31-	AMDLGP...	31		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9NVS9-81-unknown	MCLATC...	81	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000463919
Q9NVS9-96-unknown	MLLLKG...	96	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000437480
Q9NVS9-173-unknown	HQSSVI...	173	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8112
Q9NVS9-239-unknown	GDSPLG...	239	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6817

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GAVVSH	172	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8112
...QDQEVP	200	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463919
...RGLPTG	238	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6817
...ERLAP	261	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	172	VVSH.\|.HQSS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	238	LPTG.\|.GDSP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)