P62333: 26S proteasome regulatory subunit 10B

General Information

Protein names	- 26S proteasome regulatory subunit 10B - 26S proteasome AAA-ATPase subunit RPT4 - Proteasome 26S subunit ATPase 6 - Proteasome subunit p42
Gene names	PSMC6
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P62333

8 N-termini

10 C-termini

7 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADPRDKALQ DYRKKLLEHK EIDGRLKELR EQLKELTKQY EKSENDLKAL QSVGQIVGEV
        70         80         90        100        110        120
LKQLTEEKFI VKATNGPRYV VGCRRQLDKS KLKPGTRVAL DMTTLTIMRY LPREVDPLVY
       130        140        150        160        170        180
NMSHEDPGNV SYSEIGGLSE QIRELREVIE LPLTNPELFQ RVGIIPPKGC LLYGPPGTGK
       190        200        210        220        230        240
TLLARAVASQ LDCNFLKVVS SSIVDKYIGE SARLIREMFN YARDHQPCII FMDEIDAIGG
       250        260        270        280        290        300
RRFSEGTSAD REIQRTLMEL LNQMDGFDTL HRVKMIMATN RPDTLDPALL RPGRLDRKIH
       310        320        330        340        350        360
IDLPNEQARL DILKIHAGPI TKHGEIDYEA IVKLSDGFNG ADLRNVCTEA GMFAIRADHD
       370        380
FVVQEDFMKA VRKVADSKKL ESKLDYKPV

Isoforms

Sequence View

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
P62333-1-unknown	MADPRD...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62333-52-unknown	SVGQIV...	52	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3884
P62333-131-	SYSEIG...	131		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P62333-189-unknown	SQLDCN...	189	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7642
P62333-189-unknown	SQLDCN...	189	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6119
P62333-262-unknown	NQMDGF...	262	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6120
P62333-263-unknown	QMDGFD...	263	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7643
P62333-266-unknown	GFDTLH...	266	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7644
P62333-382-unknown	SKLDYK...	382	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11771

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...LKALQS	51	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3884
...ARAVAS	188	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7642
...ARAVAS	188	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6119
...IFMDEI	234	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000452048
...LMELLN	261	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6120
...MELLNQ	262	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7643
...LNQMDG	265	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7644
...VCTEAG	350	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000451156
...SKKLES	381	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11771
...DYKPV	389	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...DYKPV	389		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...DYKPV	389		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	51	ALQS.\|.SVGQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	188	AVAS.\|.SQLD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	188	AVAS.\|.SQLD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	261	ELLN.\|.NQMD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	262	LLNQ.\|.QMDG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	265	QMDG.\|.GFDT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	381	KLES.\|.SKLD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

TopFIND

P62333: 26S proteasome regulatory subunit 10B

General Information

8

N-termini

10

C-termini

7

Cleavages

0

Substrates

Sequence

Isoforms

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Protein Neighborhood

Domains & Features

8 N-termini - 10 C-termini - 7 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates