P12532: Creatine kinase U-type, mitochondrial

General Information

Protein names	- Creatine kinase U-type, mitochondrial - 2.7.3.2 - Acidic-type mitochondrial creatine kinase - Mia-CK - Ubiquitous mitochondrial creatine kinase - U-MtCK
Gene names	CKMT1B
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P12532

5 N-termini

4 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGPFSRLLS ARPGLRLLAL AGAGSLAAGF LLRPEPVRAA SERRRLYPPS AEYPDLRKHN
        70         80         90        100        110        120
NCMASHLTPA VYARLCDKTT PTGWTLDQCI QTGVDNPGHP FIKTVGMVAG DEETYEVFAD
       130        140        150        160        170        180
LFDPVIQERH NGYDPRTMKH TTDLDASKIR SGYFDERYVL SSRVRTGRSI RGLSLPPACT
       190        200        210        220        230        240
RAERREVERV VVDALSGLKG DLAGRYYRLS EMTEAEQQQL IDDHFLFDKP VSPLLTAAGM
       250        260        270        280        290        300
ARDWPDARGI WHNNEKSFLI WVNEEDHTRV ISMEKGGNMK RVFERFCRGL KEVERLIQER
       310        320        330        340        350        360
GWEFMWNERL GYILTCPSNL GTGLRAGVHI KLPLLSKDSR FPKILENLRL QKRGTGGVDT
       370        380        390        400        410
AATGGVFDIS NLDRLGKSEV ELVQLVIDGV NYLIDCERRL ERGQDIRIPT PVIHTKH

Isoforms

- Isoform 2 of Creatine kinase U-type, mitochondrial

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P12532-1-unknown	MAGPFS...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78835
P12532-40-unknown	ASERRR...	40	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P12532-92-unknown	TGVDNP...	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7301
P12532-92-unknown	TGVDNP...	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5580
P12532-92-unknown	TGVDNP...	92	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143610
P12532-364-unknown	GGVFDI...	364	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3633
P12532-364-unknown	GGVFDI...	364	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151914
P12532-365-unknown	GVFDIS...	365	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3635
P12532-365-unknown	GVFDIS...	365	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151936

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DQCIQT	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7301
...DQCIQT	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5580
...DQCIQT	91	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126852
...DTAATG	363	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3633
...DTAATG	363	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135322
...TAATGG	364	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3635
...TAATGG	364	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135344
...IHTKH	417	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...IHTKH	417	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74453

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	91	CIQT.\|.TGVD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	91	CIQT.\|.TGVD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	363	AATG.\|.GGVF	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	364	ATGG.\|.GVFD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)