Q5T4S7: E3 ubiquitin-protein ligase UBR4
| Protein names | - E3 ubiquitin-protein ligase UBR4 - 2.3.2.27 - 600 kDa retinoblastoma protein-associated factor - N-recognin-4 - RING-type E3 ubiquitin transferase UBR4 - Retinoblastoma-associated factor of 600 kDa - RBAF600 - p600 - Zinc finger UBR1-type protein 1 |
|---|---|
| Gene names | UBR4 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q5T4S7 |
14
N-termini
7
C-termini
6
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MATSGGEEAA AAAPAPGTPA TGADTTPGWE VAVRPLLSAS YSAFEMKELP QLVASVIESE
70 80 90 100 110 120
SEILHHEKQY EPFYSSFVAL STHYITTVCS LIPRNQLQSV AAACKVLIEF SLLRLENPDE
130 140 150 160 170 180
ACAVSQKHLI LLIKGLCTGC SRLDRTEIIT FTAMMKSAKL PQTVKTLSDV EDQKELASPV
190 200 210 220 230 240
SPELRQKEVQ MNFLNQLTSV FNPRTVASQP ISTQTLVEGE NDEQSSTDQA SAIKTKNVFI
250 260 270 280 290 300
AQNVASLQEL GGSEKLLRVC LNLPYFLRYI NRFQDAVLAN SFFIMPATVA DATAVRNGFH
310 320 330 340 350 360
SLVIDVTMAL DTLSLPVLEP LNPSRLQDVT VLSLSCLYAG VSVATCMAIL HVGSAQQVRT
370 380 390 400 410 420
GSTSSKEDDY ESDAATIVQK CLEIYDMIGQ AISSSRRAGG EHYQNFQLLG AWCLLNSLFL
430 440 450 460 470 480
ILNLSPTALA DKGKEKDPLA ALRVRDILSR TKEGVGSPKL GPGKGHQGFG VLSVILANHA
490 500 510 520 530 540
IKLLTSLFQD LQVEALHKGW ETDGPPAALS IMAQSTSIQR IQRLIDSVPL MNLLLTLLST
550 560 570 580 590 600
SYRKACVLQR QRKGSMSSDA SASTDSNTYY EDDFSSTEED SSQDDDSEPI LGQWFEETIS
610 620 630 640 650 660
PSKEKAAPPP PPPPPPLESS PRVKSPSKQA PGEKGNILAS RKDPELFLGL ASNILNFITS
670 680 690 700 710 720
SMLNSRNNFI RNYLSVSLSE HHMATLASII KEVDKDGLKG SSDEEFAAAL YHFNHSLVTS
730 740 750 760 770 780
DLQSPNLQNT LLQQLGVAPF SEGPWPLYIH PQSLSVLSRL LLIWQHKASA QGDPDVPECL
790 800 810 820 830 840
KVWDRFLSTM KQNALQGVVP SETEDLNVEH LQMLLLIFHN FTETGRRAIL SLFVQIIQEL
850 860 870 880 890 900
SVNMDAQMRF VPLILARLLL IFDYLLHQYS KAPVYLFEQV QHNLLSPPFG WASGSQDSNS
910 920 930 940 950 960
RRATTPLYHG FKEVEENWSK HFSSDAVPHP RFYCVLSPEA SEDDLNRLDS VACDVLFSKL
970 980 990 1000 1010 1020
VKYDELYAAL TALLAAGSQL DTVRRKENKN VTALEACALQ YYFLILWRIL GILPPSKTYI
1030 1040 1050 1060 1070 1080
NQLSMNSPEM SECDILHTLR WSSRLRISSY VNWIKDHLIK QGMKAEHASS LLELASTTKC
1090 1100 1110 1120 1130 1140
SSVKYDVEIV EEYFARQISS FCSIDCTTIL QLHEIPSLQS IYTLDAAISK VQVSLDEHFS
1150 1160 1170 1180 1190 1200
KMAAETDPHK SSEITKNLLP ATLQLIDTYA SFTRAYLLQN FNEEGTTEKP SKEKLQGFAA
1210 1220 1230 1240 1250 1260
VLAIGSSRCK ANTLGPTLVQ NLPSSVQTVC ESWNNINTNE FPNIGSWRNA FANDTIPSES
1270 1280 1290 1300 1310 1320
YISAVQAAHL GTLCSQSLPL AASLKHTLLS LVRLTGDLIV WSDEMNPPQV IRTLLPLLLE
1330 1340 1350 1360 1370 1380
SSTESVAEIS SNSLERILGP AESDEFLARV YEKLITGCYN ILANHADPNS GLDESILEEC
1390 1400 1410 1420 1430 1440
LQYLEKQLES SQARKAMEEF FSDSGELVQI MMATANENLS AKFCNRVLKF FTKLFQLTEK
1450 1460 1470 1480 1490 1500
SPNPSLLHLC GSLAQLACVE PVRLQAWLTR MTTSPPKDSD QLDVIQENRQ LLQLLTTYIV
1510 1520 1530 1540 1550 1560
RENSQVGEGV CAVLLGTLTP MATEMLANGD GTGFPELMVV MATLASAGQG AGHLQLHNAA
1570 1580 1590 1600 1610 1620
VDWLSRCKKY LSQKNVVEKL NANVMHGKHV MILECTCHIM SYLADVTNAL SQSNGQGPSH
1630 1640 1650 1660 1670 1680
LSVDGEERAI EVDSDWVEEL AVEEEDSQAE DSDEDSLCNK LCTFTITQKE FMNQHWYHCH
1690 1700 1710 1720 1730 1740
TCKMVDGVGV CTVCAKVCHK DHEISYAKYG SFFCDCGAKE DGSCLALVKR TPSSGMSSTM
1750 1760 1770 1780 1790 1800
KESAFQSEPR ISESLVRHAS TSSPADKAKV TISDGKVADE EKPKKSSLCR TVEGCREELQ
1810 1820 1830 1840 1850 1860
NQANFSFAPL VLDMLNFLMD AIQTNFQQAS AVGSSSRAQQ ALSELHTVEK AVEMTDQLMV
1870 1880 1890 1900 1910 1920
PTLGSQEGAF ENVRMNYSGD QGQTIRQLIS AHVLRRVAMC VLSSPHGRRQ HLAVSHEKGK
1930 1940 1950 1960 1970 1980
ITVLQLSALL KQADSSKRKL TLTRLASAPV PFTVLSLTGN PCKEDYLAVC GLKDCHVLTF
1990 2000 2010 2020 2030 2040
SSSGSVSDHL VLHPQLATGN FIIKAVWLPG SQTELAIVTA DFVKIYDLCV DALSPTFYFL
2050 2060 2070 2080 2090 2100
LPSSKIRDVT FLFNEEGKNI IVIMSSAGYI YTQLMEEASS AQQGPFYVTN VLEINHEDLK
2110 2120 2130 2140 2150 2160
DSNSQVAGGG VSVYYSHVLQ MLFFSYCQGK SFAATISRTT LEVLQLFPIN IKSSNGGSKT
2170 2180 2190 2200 2210 2220
SPALCQWSEV MNHPGLVCCV QQTTGVPLVV MVKPDTFLIQ EIKTLPAKAK IQDMVAIRHT
2230 2240 2250 2260 2270 2280
ACNEQQRTTM ILLCEDGSLR IYMANVENTS YWLQPSLQPS SVISIMKPVR KRKTATITTR
2290 2300 2310 2320 2330 2340
TSSQVTFPID FFEHNQQLTD VEFGGNDLLQ VYNAQQIKHR LNSTGMYVAN TKPGGFTIEI
2350 2360 2370 2380 2390 2400
SNNNSTMVMT GMRIQIGTQA IERAPSYIEI FGRTMQLNLS RSRWFDFPFT REEALQADKK
2410 2420 2430 2440 2450 2460
LNLFIGASVD PAGVTMIDAV KIYGKTKEQF GWPDEPPEEF PSASVSNICP SNLNQSNGTG
2470 2480 2490 2500 2510 2520
DSDSAAPTTT SGTVLERLVV SSLEALESCF AVGPIIEKER NKNAAQELAT LLLSLPAPAS
2530 2540 2550 2560 2570 2580
VQQQSKSLLA SLHTSRSAYH SHKDQALLSK AVQCLNTSSK EGKDLDPEVF QRLVITARSI
2590 2600 2610 2620 2630 2640
AIMRPNNLVH FTESKLPQME TEGMDEGKEP QKQLEGDCCS FITQLVNHFW KLHASKPKNA
2650 2660 2670 2680 2690 2700
FLAPACLPGL THIEATVNAL VDIIHGYCTC ELDCINTASK IYMQMLLCPD PAVSFSCKQA
2710 2720 2730 2740 2750 2760
LIRVLRPRNK RRHVTLPSSP RSNTPMGDKD DDDDDDADEK MQSSGIPNGG HIRQESQEQS
2770 2780 2790 2800 2810 2820
EVDHGDFEMV SESMVLETAE NVNNGNPSPL EALLAGAEGF PPMLDIPPDA DDETMVELAI
2830 2840 2850 2860 2870 2880
ALSLQQDQQG SSSSALGLQS LGLSGQAPSS SSLDAGTLSD TTASAPASDD EGSTAATDGS
2890 2900 2910 2920 2930 2940
TLRTSPADHG GSVGSESGGS AVDSVAGEHS VSGRSSAYGD ATAEGHPAGP GSVSSSTGAI
2950 2960 2970 2980 2990 3000
STTTGHQEGD GSEGEGEGET EGDVHTSNRL HMVRLMLLER LLQTLPQLRN VGGVRAIPYM
3010 3020 3030 3040 3050 3060
QVILMLTTDL DGEDEKDKGA LDNLLSQLIA ELGMDKKDVS KKNERSALNE VHLVVMRLLS
3070 3080 3090 3100 3110 3120
VFMSRTKSGS KSSICESSSL ISSATAAALL SSGAVDYCLH VLKSLLEYWK SQQNDEEPVA
3130 3140 3150 3160 3170 3180
TSQLLKPHTT SSPPDMSPFF LRQYVKGHAA DVFEAYTQLL TEMVLRLPYQ IKKITDTNSR
3190 3200 3210 3220 3230 3240
IPPPVFDHSW FYFLSEYLMI QQTPFVRRQV RKLLLFICGS KEKYRQLRDL HTLDSHVRGI
3250 3260 3270 3280 3290 3300
KKLLEEQGIF LRASVVTASS GSALQYDTLI SLMEHLKACA EIAAQRTINW QKFCIKDDSV
3310 3320 3330 3340 3350 3360
LYFLLQVSFL VDEGVSPVLL QLLSCALCGS KVLAALAASS GSSSASSSSA PVAASSGQAT
3370 3380 3390 3400 3410 3420
TQSKSSTKKS KKEEKEKEKD GETSGSQEDQ LCTALVNQLN KFADKETLIQ FLRCFLLESN
3430 3440 3450 3460 3470 3480
SSSVRWQAHC LTLHIYRNSS KSQQELLLDL MWSIWPELPA YGRKAAQFVD LLGYFSLKTP
3490 3500 3510 3520 3530 3540
QTEKKLKEYS QKAVEILRTQ NHILTNHPNS NIYNTLSGLV EFDGYYLESD PCLVCNNPEV
3550 3560 3570 3580 3590 3600
PFCYIKLSSI KVDTRYTTTQ QVVKLIGSHT ISKVTVKIGD LKRTKMVRTI NLYYNNRTVQ
3610 3620 3630 3640 3650 3660
AIVELKNKPA RWHKAKKVQL TPGQTEVKID LPLPIVASNL MIEFADFYEN YQASTETLQC
3670 3680 3690 3700 3710 3720
PRCSASVPAN PGVCGNCGEN VYQCHKCRSI NYDEKDPFLC NACGFCKYAR FDFMLYAKPC
3730 3740 3750 3760 3770 3780
CAVDPIENEE DRKKAVSNIN TLLDKADRVY HQLMGHRPQL ENLLCKVNEA APEKPQDDSG
3790 3800 3810 3820 3830 3840
TAGGISSTSA SVNRYILQLA QEYCGDCKNS FDELSKIIQK VFASRKELLE YDLQQREAAT
3850 3860 3870 3880 3890 3900
KSSRTSVQPT FTASQYRALS VLGCGHTSST KCYGCASAVT EHCITLLRAL ATNPALRHIL
3910 3920 3930 3940 3950 3960
VSQGLIRELF DYNLRRGAAA MREEVRQLMC LLTRDNPEAT QQMNDLIIGK VSTALKGHWA
3970 3980 3990 4000 4010 4020
NPDLASSLQY EMLLLTDSIS KEDSCWELRL RCALSLFLMA VNIKTPVVVE NITLMCLRIL
4030 4040 4050 4060 4070 4080
QKLIKPPAPT SKKNKDVPVE ALTTVKPYCN EIHAQAQLWL KRDPKASYDA WKKCLPIRGI
4090 4100 4110 4120 4130 4140
DGNGKAPSKS ELRHLYLTEK YVWRWKQFLS RRGKRTSPLD LKLGHNNWLR QVLFTPATQA
4150 4160 4170 4180 4190 4200
ARQAACTIVE ALATIPSRKQ QVLDLLTSYL DELSIAGECA AEYLALYQKL ITSAHWKVYL
4210 4220 4230 4240 4250 4260
AARGVLPYVG NLITKEIARL LALEEATLST DLQQGYALKS LTGLLSSFVE VESIKRHFKS
4270 4280 4290 4300 4310 4320
RLVGTVLNGY LCLRKLVVQR TKLIDETQDM LLEMLEDMTT GTESETKAFM AVCIETAKRY
4330 4340 4350 4360 4370 4380
NLDDYRTPVF IFERLCSIIY PEENEVTEFF VTLEKDPQQE DFLQGRMPGN PYSSNEPGIG
4390 4400 4410 4420 4430 4440
PLMRDIKNKI CQDCDLVALL EDDSGMELLV NNKIISLDLP VAEVYKKVWC TTNEGEPMRI
4450 4460 4470 4480 4490 4500
VYRMRGLLGD ATEEFIESLD STTDEEEDEE EVYKMAGVMA QCGGLECMLN RLAGIRDFKQ
4510 4520 4530 4540 4550 4560
GRHLLTVLLK LFSYCVKVKV NRQQLVKLEM NTLNVMLGTL NLALVAEQES KDSGGAAVAE
4570 4580 4590 4600 4610 4620
QVLSIMEIIL DESNAEPLSE DKGNLLLTGD KDQLVMLLDQ INSTFVRSNP SVLQGLLRII
4630 4640 4650 4660 4670 4680
PYLSFGEVEK MQILVERFKP YCNFDKYDED HSGDDKVFLD CFCKIAAGIK NNSNGHQLKD
4690 4700 4710 4720 4730 4740
LILQKGITQN ALDYMKKHIP SAKNLDADIW KKFLSRPALP FILRLLRGLA IQHPGTQVLI
4750 4760 4770 4780 4790 4800
GTDSIPNLHK LEQVSSDEGI GTLAENLLEA LREHPDVNKK IDAARRETRA EKKRMAMAMR
4810 4820 4830 4840 4850 4860
QKALGTLGMT TNEKGQVVTK TALLKQMEEL IEEPGLTCCI CREGYKFQPT KVLGIYTFTK
4870 4880 4890 4900 4910 4920
RVALEEMENK PRKQQGYSTV SHFNIVHYDC HLAAVRLARG REEWESAALQ NANTKCNGLL
4930 4940 4950 4960 4970 4980
PVWGPHVPES AFATCLARHN TYLQECTGQR EPTYQLNIHD IKLLFLRFAM EQSFSADTGG
4990 5000 5010 5020 5030 5040
GGRESNIHLI PYIIHTVLYV LNTTRATSRE EKNLQGFLEQ PKEKWVESAF EVDGPYYFTV
5050 5060 5070 5080 5090 5100
LALHILPPEQ WRATRVEILR RLLVTSQARA VAPGGATRLT DKAVKDYSAY RSSLLFWALV
5110 5120 5130 5140 5150 5160
DLIYNMFKKV PTSNTEGGWS CSLAEYIRHN DMPIYEAADK ALKTFQEEFM PVETFSEFLD
5170 5180
VAGLLSEITD PESFLKDLLN SVP
Isoforms
- Isoform 2 of E3 ubiquitin-protein ligase UBR4 - Isoform 3 of E3 ubiquitin-protein ligase UBR4 - Isoform 4 of E3 ubiquitin-protein ligase UBR4 - Isoform 5 of E3 ubiquitin-protein ligase UBR4 - Isoform 6 of E3 ubiquitin-protein ligase UBR4Sequence View
10 20 30 40 50 60
MATSGGEEAA AAAPAPGTPA TGADTTPGWE VAVRPLLSAS YSAFEMKELP QLVASVIESE
70 80 90 100 110 120
SEILHHEKQY EPFYSSFVAL STHYITTVCS LIPRNQLQSV AAACKVLIEF SLLRLENPDE
130 140 150 160 170 180
ACAVSQKHLI LLIKGLCTGC SRLDRTEIIT FTAMMKSAKL PQTVKTLSDV EDQKELASPV
190 200 210 220 230 240
SPELRQKEVQ MNFLNQLTSV FNPRTVASQP ISTQTLVEGE NDEQSSTDQA SAIKTKNVFI
250 260 270 280 290 300
AQNVASLQEL GGSEKLLRVC LNLPYFLRYI NRFQDAVLAN SFFIMPATVA DATAVRNGFH
310 320 330 340 350 360
SLVIDVTMAL DTLSLPVLEP LNPSRLQDVT VLSLSCLYAG VSVATCMAIL HVGSAQQVRT
370 380 390 400 410 420
GSTSSKEDDY ESDAATIVQK CLEIYDMIGQ AISSSRRAGG EHYQNFQLLG AWCLLNSLFL
430 440 450 460 470 480
ILNLSPTALA DKGKEKDPLA ALRVRDILSR TKEGVGSPKL GPGKGHQGFG VLSVILANHA
490 500 510 520 530 540
IKLLTSLFQD LQVEALHKGW ETDGPPAALS IMAQSTSIQR IQRLIDSVPL MNLLLTLLST
550 560 570 580 590 600
SYRKACVLQR QRKGSMSSDA SASTDSNTYY EDDFSSTEED SSQDDDSEPI LGQWFEETIS
610 620 630 640 650 660
PSKEKAAPPP PPPPPPLESS PRVKSPSKQA PGEKGNILAS RKDPELFLGL ASNILNFITS
670 680 690 700 710 720
SMLNSRNNFI RNYLSVSLSE HHMATLASII KEVDKDGLKG SSDEEFAAAL YHFNHSLVTS
730 740 750 760 770 780
DLQSPNLQNT LLQQLGVAPF SEGPWPLYIH PQSLSVLSRL LLIWQHKASA QGDPDVPECL
790 800 810 820 830 840
KVWDRFLSTM KQNALQGVVP SETEDLNVEH LQMLLLIFHN FTETGRRAIL SLFVQIIQEL
850 860 870 880 890 900
SVNMDAQMRF VPLILARLLL IFDYLLHQYS KAPVYLFEQV QHNLLSPPFG WASGSQDSNS
910 920 930 940 950 960
RRATTPLYHG FKEVEENWSK HFSSDAVPHP RFYCVLSPEA SEDDLNRLDS VACDVLFSKL
970 980 990 1000 1010 1020
VKYDELYAAL TALLAAGSQL DTVRRKENKN VTALEACALQ YYFLILWRIL GILPPSKTYI
1030 1040 1050 1060 1070 1080
NQLSMNSPEM SECDILHTLR WSSRLRISSY VNWIKDHLIK QGMKAEHASS LLELASTTKC
1090 1100 1110 1120 1130 1140
SSVKYDVEIV EEYFARQISS FCSIDCTTIL QLHEIPSLQS IYTLDAAISK VQVSLDEHFS
1150 1160 1170 1180 1190 1200
KMAAETDPHK SSEITKNLLP ATLQLIDTYA SFTRAYLLQN FNEEGTTEKP SKEKLQGFAA
1210 1220 1230 1240 1250 1260
VLAIGSSRCK ANTLGPTLVQ NLPSSVQTVC ESWNNINTNE FPNIGSWRNA FANDTIPSES
1270 1280 1290 1300 1310 1320
YISAVQAAHL GTLCSQSLPL AASLKHTLLS LVRLTGDLIV WSDEMNPPQV IRTLLPLLLE
1330 1340 1350 1360 1370 1380
SSTESVAEIS SNSLERILGP AESDEFLARV YEKLITGCYN ILANHADPNS GLDESILEEC
1390 1400 1410 1420 1430 1440
LQYLEKQLES SQARKAMEEF FSDSGELVQI MMATANENLS AKFCNRVLKF FTKLFQLTEK
1450 1460 1470 1480 1490 1500
SPNPSLLHLC GSLAQLACVE PVRLQAWLTR MTTSPPKDSD QLDVIQENRQ LLQLLTTYIV
1510 1520 1530 1540 1550 1560
RENSQVGEGV CAVLLGTLTP MATEMLANGD GTGFPELMVV MATLASAGQG AGHLQLHNAA
1570 1580 1590 1600 1610 1620
VDWLSRCKKY LSQKNVVEKL NANVMHGKHV MILECTCHIM SYLADVTNAL SQSNGQGPSH
1630 1640 1650 1660 1670 1680
LSVDGEERAI EVDSDWVEEL AVEEEDSQAE DSDEDSLCNK LCTFTITQKE FMNQHWYHCH
1690 1700 1710 1720 1730 1740
TCKMVDGVGV CTVCAKVCHK DHEISYAKYG SFFCDCGAKE DGSCLALVKR TPSSGMSSTM
1750 1760 1770 1780 1790 1800
KESAFQSEPR ISESLVRHAS TSSPADKAKV TISDGKVADE EKPKKSSLCR TVEGCREELQ
1810 1820 1830 1840 1850 1860
NQANFSFAPL VLDMLNFLMD AIQTNFQQAS AVGSSSRAQQ ALSELHTVEK AVEMTDQLMV
1870 1880 1890 1900 1910 1920
PTLGSQEGAF ENVRMNYSGD QGQTIRQLIS AHVLRRVAMC VLSSPHGRRQ HLAVSHEKGK
1930 1940 1950 1960 1970 1980
ITVLQLSALL KQADSSKRKL TLTRLASAPV PFTVLSLTGN PCKEDYLAVC GLKDCHVLTF
1990 2000 2010 2020 2030 2040
SSSGSVSDHL VLHPQLATGN FIIKAVWLPG SQTELAIVTA DFVKIYDLCV DALSPTFYFL
2050 2060 2070 2080 2090 2100
LPSSKIRDVT FLFNEEGKNI IVIMSSAGYI YTQLMEEASS AQQGPFYVTN VLEINHEDLK
2110 2120 2130 2140 2150 2160
DSNSQVAGGG VSVYYSHVLQ MLFFSYCQGK SFAATISRTT LEVLQLFPIN IKSSNGGSKT
2170 2180 2190 2200 2210 2220
SPALCQWSEV MNHPGLVCCV QQTTGVPLVV MVKPDTFLIQ EIKTLPAKAK IQDMVAIRHT
2230 2240 2250 2260 2270 2280
ACNEQQRTTM ILLCEDGSLR IYMANVENTS YWLQPSLQPS SVISIMKPVR KRKTATITTR
2290 2300 2310 2320 2330 2340
TSSQVTFPID FFEHNQQLTD VEFGGNDLLQ VYNAQQIKHR LNSTGMYVAN TKPGGFTIEI
2350 2360 2370 2380 2390 2400
SNNNSTMVMT GMRIQIGTQA IERAPSYIEI FGRTMQLNLS RSRWFDFPFT REEALQADKK
2410 2420 2430 2440 2450 2460
LNLFIGASVD PAGVTMIDAV KIYGKTKEQF GWPDEPPEEF PSASVSNICP SNLNQSNGTG
2470 2480 2490 2500 2510 2520
DSDSAAPTTT SGTVLERLVV SSLEALESCF AVGPIIEKER NKNAAQELAT LLLSLPAPAS
2530 2540 2550 2560 2570 2580
VQQQSKSLLA SLHTSRSAYH SHKDQALLSK AVQCLNTSSK EGKDLDPEVF QRLVITARSI
2590 2600 2610 2620 2630 2640
AIMRPNNLVH FTESKLPQME TEGMDEGKEP QKQLEGDCCS FITQLVNHFW KLHASKPKNA
2650 2660 2670 2680 2690 2700
FLAPACLPGL THIEATVNAL VDIIHGYCTC ELDCINTASK IYMQMLLCPD PAVSFSCKQA
2710 2720 2730 2740 2750 2760
LIRVLRPRNK RRHVTLPSSP RSNTPMGDKD DDDDDDADEK MQSSGIPNGG HIRQESQEQS
2770 2780 2790 2800 2810 2820
EVDHGDFEMV SESMVLETAE NVNNGNPSPL EALLAGAEGF PPMLDIPPDA DDETMVELAI
2830 2840 2850 2860 2870 2880
ALSLQQDQQG SSSSALGLQS LGLSGQAPSS SSLDAGTLSD TTASAPASDD EGSTAATDGS
2890 2900 2910 2920 2930 2940
TLRTSPADHG GSVGSESGGS AVDSVAGEHS VSGRSSAYGD ATAEGHPAGP GSVSSSTGAI
2950 2960 2970 2980 2990 3000
STTTGHQEGD GSEGEGEGET EGDVHTSNRL HMVRLMLLER LLQTLPQLRN VGGVRAIPYM
3010 3020 3030 3040 3050 3060
QVILMLTTDL DGEDEKDKGA LDNLLSQLIA ELGMDKKDVS KKNERSALNE VHLVVMRLLS
3070 3080 3090 3100 3110 3120
VFMSRTKSGS KSSICESSSL ISSATAAALL SSGAVDYCLH VLKSLLEYWK SQQNDEEPVA
3130 3140 3150 3160 3170 3180
TSQLLKPHTT SSPPDMSPFF LRQYVKGHAA DVFEAYTQLL TEMVLRLPYQ IKKITDTNSR
3190 3200 3210 3220 3230 3240
IPPPVFDHSW FYFLSEYLMI QQTPFVRRQV RKLLLFICGS KEKYRQLRDL HTLDSHVRGI
3250 3260 3270 3280 3290 3300
KKLLEEQGIF LRASVVTASS GSALQYDTLI SLMEHLKACA EIAAQRTINW QKFCIKDDSV
3310 3320 3330 3340 3350 3360
LYFLLQVSFL VDEGVSPVLL QLLSCALCGS KVLAALAASS GSSSASSSSA PVAASSGQAT
3370 3380 3390 3400 3410 3420
TQSKSSTKKS KKEEKEKEKD GETSGSQEDQ LCTALVNQLN KFADKETLIQ FLRCFLLESN
3430 3440 3450 3460 3470 3480
SSSVRWQAHC LTLHIYRNSS KSQQELLLDL MWSIWPELPA YGRKAAQFVD LLGYFSLKTP
3490 3500 3510 3520 3530 3540
QTEKKLKEYS QKAVEILRTQ NHILTNHPNS NIYNTLSGLV EFDGYYLESD PCLVCNNPEV
3550 3560 3570 3580 3590 3600
PFCYIKLSSI KVDTRYTTTQ QVVKLIGSHT ISKVTVKIGD LKRTKMVRTI NLYYNNRTVQ
3610 3620 3630 3640 3650 3660
AIVELKNKPA RWHKAKKVQL TPGQTEVKID LPLPIVASNL MIEFADFYEN YQASTETLQC
3670 3680 3690 3700 3710 3720
PRCSASVPAN PGVCGNCGEN VYQCHKCRSI NYDEKDPFLC NACGFCKYAR FDFMLYAKPC
3730 3740 3750 3760 3770 3780
CAVDPIENEE DRKKAVSNIN TLLDKADRVY HQLMGHRPQL ENLLCKVNEA APEKPQDDSG
3790 3800 3810 3820 3830 3840
TAGGISSTSA SVNRYILQLA QEYCGDCKNS FDELSKIIQK VFASRKELLE YDLQQREAAT
3850 3860 3870 3880 3890 3900
KSSRTSVQPT FTASQYRALS VLGCGHTSST KCYGCASAVT EHCITLLRAL ATNPALRHIL
3910 3920 3930 3940 3950 3960
VSQGLIRELF DYNLRRGAAA MREEVRQLMC LLTRDNPEAT QQMNDLIIGK VSTALKGHWA
3970 3980 3990 4000 4010 4020
NPDLASSLQY EMLLLTDSIS KEDSCWELRL RCALSLFLMA VNIKTPVVVE NITLMCLRIL
4030 4040 4050 4060 4070 4080
QKLIKPPAPT SKKNKDVPVE ALTTVKPYCN EIHAQAQLWL KRDPKASYDA WKKCLPIRGI
4090 4100 4110 4120 4130 4140
DGNGKAPSKS ELRHLYLTEK YVWRWKQFLS RRGKRTSPLD LKLGHNNWLR QVLFTPATQA
4150 4160 4170 4180 4190 4200
ARQAACTIVE ALATIPSRKQ QVLDLLTSYL DELSIAGECA AEYLALYQKL ITSAHWKVYL
4210 4220 4230 4240 4250 4260
AARGVLPYVG NLITKEIARL LALEEATLST DLQQGYALKS LTGLLSSFVE VESIKRHFKS
4270 4280 4290 4300 4310 4320
RLVGTVLNGY LCLRKLVVQR TKLIDETQDM LLEMLEDMTT GTESETKAFM AVCIETAKRY
4330 4340 4350 4360 4370 4380
NLDDYRTPVF IFERLCSIIY PEENEVTEFF VTLEKDPQQE DFLQGRMPGN PYSSNEPGIG
4390 4400 4410 4420 4430 4440
PLMRDIKNKI CQDCDLVALL EDDSGMELLV NNKIISLDLP VAEVYKKVWC TTNEGEPMRI
4450 4460 4470 4480 4490 4500
VYRMRGLLGD ATEEFIESLD STTDEEEDEE EVYKMAGVMA QCGGLECMLN RLAGIRDFKQ
4510 4520 4530 4540 4550 4560
GRHLLTVLLK LFSYCVKVKV NRQQLVKLEM NTLNVMLGTL NLALVAEQES KDSGGAAVAE
4570 4580 4590 4600 4610 4620
QVLSIMEIIL DESNAEPLSE DKGNLLLTGD KDQLVMLLDQ INSTFVRSNP SVLQGLLRII
4630 4640 4650 4660 4670 4680
PYLSFGEVEK MQILVERFKP YCNFDKYDED HSGDDKVFLD CFCKIAAGIK NNSNGHQLKD
4690 4700 4710 4720 4730 4740
LILQKGITQN ALDYMKKHIP SAKNLDADIW KKFLSRPALP FILRLLRGLA IQHPGTQVLI
4750 4760 4770 4780 4790 4800
GTDSIPNLHK LEQVSSDEGI GTLAENLLEA LREHPDVNKK IDAARRETRA EKKRMAMAMR
4810 4820 4830 4840 4850 4860
QKALGTLGMT TNEKGQVVTK TALLKQMEEL IEEPGLTCCI CREGYKFQPT KVLGIYTFTK
4870 4880 4890 4900 4910 4920
RVALEEMENK PRKQQGYSTV SHFNIVHYDC HLAAVRLARG REEWESAALQ NANTKCNGLL
4930 4940 4950 4960 4970 4980
PVWGPHVPES AFATCLARHN TYLQECTGQR EPTYQLNIHD IKLLFLRFAM EQSFSADTGG
4990 5000 5010 5020 5030 5040
GGRESNIHLI PYIIHTVLYV LNTTRATSRE EKNLQGFLEQ PKEKWVESAF EVDGPYYFTV
5050 5060 5070 5080 5090 5100
LALHILPPEQ WRATRVEILR RLLVTSQARA VAPGGATRLT DKAVKDYSAY RSSLLFWALV
5110 5120 5130 5140 5150 5160
DLIYNMFKKV PTSNTEGGWS CSLAEYIRHN DMPIYEAADK ALKTFQEEFM PVETFSEFLD
5170 5180
VAGLLSEITD PESFLKDLLN SVP
10 20 30 40 50 60
MATSGGEEAA AAAPAPGTPA TGADTTPGWE VAVRPLLSAS YSAFEMKELP QLVASVIESE
70 80 90 100 110 120
SEILHHEKQY EPFYSSFVAL STHYITTVCS LIPRNQLQSV AAACKVLIEF SLLRLENPDE
130 140 150 160 170 180
ACAVSQKHLI LLIKGLCTGC SRLDRTEIIT FTAMMKSAKL PQTVKTLSDV EDQKELASPV
190 200 210 220 230 240
SPELRQKEVQ MNFLNQLTSV FNPRTVASQP ISTQTLVEGE NDEQSSTDQA SAIKTKNVFI
250 260 270 280 290 300
AQNVASLQEL GGSEKLLRVC LNLPYFLRYI NRFQDAVLAN SFFIMPATVA DATAVRNGFH
310 320 330 340 350 360
SLVIDVTMAL DTLSLPVLEP LNPSRLQDVT VLSLSCLYAG VSVATCMAIL HVGSAQQVRT
370 380 390 400 410 420
GSTSSKEDDY ESDAATIVQK CLEIYDMIGQ AISSSRRAGG EHYQNFQLLG AWCLLNSLFL
430 440 450 460 470 480
ILNLSPTALA DKGKEKDPLA ALRVRDILSR TKEGVGSPKL GPGKGHQGFG VLSVILANHA
490 500 510 520 530 540
IKLLTSLFQD LQVEALHKGW ETDGPPAALS IMAQSTSIQR IQRLIDSVPL MNLLLTLLST
550 560 570 580 590 600
SYRKACVLQR QRKGSMSSDA SASTDSNTYY EDDFSSTEED SSQDDDSEPI LGQWFEETIS
610 620 630 640 650 660
PSKEKAAPPP PPPPPPLESS PRVKSPSKQA PGEKGNILAS RKDPELFLGL ASNILNFITS
670 680 690 700 710 720
SMLNSRNNFI RNYLSVSLSE HHMATLASII KEVDKDGLKG SSDEEFAAAL YHFNHSLVTS
730 740 750 760 770 780
DLQSPNLQNT LLQQLGVAPF SEGPWPLYIH PQSLSVLSRL LLIWQHKASA QGDPDVPECL
790 800 810 820 830 840
KVWDRFLSTM KQNALQGVVP SETEDLNVEH LQMLLLIFHN FTETGRRAIL SLFVQIIQEL
850 860 870 880 890 900
SVNMDAQMRF VPLILARLLL IFDYLLHQYS KAPVYLFEQV QHNLLSPPFG WASGSQDSNS
910 920 930 940 950 960
RRATTPLYHG FKEVEENWSK HFSSDAVPHP RFYCVLSPEA SEDDLNRLDS VACDVLFSKL
970 980 990 1000 1010 1020
VKYDELYAAL TALLAAGSQL DTVRRKENKN VTALEACALQ YYFLILWRIL GILPPSKTYI
1030 1040 1050 1060 1070 1080
NQLSMNSPEM SECDILHTLR WSSRLRISSY VNWIKDHLIK QGMKAEHASS LLELASTTKC
1090 1100 1110 1120 1130 1140
SSVKYDVEIV EEYFARQISS FCSIDCTTIL QLHEIPSLQS IYTLDAAISK VQVSLDEHFS
1150 1160 1170 1180 1190 1200
KMAAETDPHK SSEITKNLLP ATLQLIDTYA SFTRAYLLQN FNEEGTTEKP SKEKLQGFAA
1210 1220 1230 1240 1250 1260
VLAIGSSRCK ANTLGPTLVQ NLPSSVQTVC ESWNNINTNE FPNIGSWRNA FANDTIPSES
1270 1280 1290 1300 1310 1320
YISAVQAAHL GTLCSQSLPL AASLKHTLLS LVRLTGDLIV WSDEMNPPQV IRTLLPLLLE
1330 1340 1350 1360 1370 1380
SSTESVAEIS SNSLERILGP AESDEFLARV YEKLITGCYN ILANHADPNS GLDESILEEC
1390 1400 1410 1420 1430 1440
LQYLEKQLES SQARKAMEEF FSDSGELVQI MMATANENLS AKFCNRVLKF FTKLFQLTEK
1450 1460 1470 1480 1490 1500
SPNPSLLHLC GSLAQLACVE PVRLQAWLTR MTTSPPKDSD QLDVIQENRQ LLQLLTTYIV
1510 1520 1530 1540 1550 1560
RENSQVGEGV CAVLLGTLTP MATEMLANGD GTGFPELMVV MATLASAGQG AGHLQLHNAA
1570 1580 1590 1600 1610 1620
VDWLSRCKKY LSQKNVVEKL NANVMHGKHV MILECTCHIM SYLADVTNAL SQSNGQGPSH
1630 1640 1650 1660 1670 1680
LSVDGEERAI EVDSDWVEEL AVEEEDSQAE DSDEDSLCNK LCTFTITQKE FMNQHWYHCH
1690 1700 1710 1720 1730 1740
TCKMVDGVGV CTVCAKVCHK DHEISYAKYG SFFCDCGAKE DGSCLALVKR TPSSGMSSTM
1750 1760 1770 1780 1790 1800
KESAFQSEPR ISESLVRHAS TSSPADKAKV TISDGKVADE EKPKKSSLCR TVEGCREELQ
1810 1820 1830 1840 1850 1860
NQANFSFAPL VLDMLNFLMD AIQTNFQQAS AVGSSSRAQQ ALSELHTVEK AVEMTDQLMV
1870 1880 1890 1900 1910 1920
PTLGSQEGAF ENVRMNYSGD QGQTIRQLIS AHVLRRVAMC VLSSPHGRRQ HLAVSHEKGK
1930 1940 1950 1960 1970 1980
ITVLQLSALL KQADSSKRKL TLTRLASAPV PFTVLSLTGN PCKEDYLAVC GLKDCHVLTF
1990 2000 2010 2020 2030 2040
SSSGSVSDHL VLHPQLATGN FIIKAVWLPG SQTELAIVTA DFVKIYDLCV DALSPTFYFL
2050 2060 2070 2080 2090 2100
LPSSKIRDVT FLFNEEGKNI IVIMSSAGYI YTQLMEEASS AQQGPFYVTN VLEINHEDLK
2110 2120 2130 2140 2150 2160
DSNSQVAGGG VSVYYSHVLQ MLFFSYCQGK SFAATISRTT LEVLQLFPIN IKSSNGGSKT
2170 2180 2190 2200 2210 2220
SPALCQWSEV MNHPGLVCCV QQTTGVPLVV MVKPDTFLIQ EIKTLPAKAK IQDMVAIRHT
2230 2240 2250 2260 2270 2280
ACNEQQRTTM ILLCEDGSLR IYMANVENTS YWLQPSLQPS SVISIMKPVR KRKTATITTR
2290 2300 2310 2320 2330 2340
TSSQVTFPID FFEHNQQLTD VEFGGNDLLQ VYNAQQIKHR LNSTGMYVAN TKPGGFTIEI
2350 2360 2370 2380 2390 2400
SNNNSTMVMT GMRIQIGTQA IERAPSYIEI FGRTMQLNLS RSRWFDFPFT REEALQADKK
2410 2420 2430 2440 2450 2460
LNLFIGASVD PAGVTMIDAV KIYGKTKEQF GWPDEPPEEF PSASVSNICP SNLNQSNGTG
2470 2480 2490 2500 2510 2520
DSDSAAPTTT SGTVLERLVV SSLEALESCF AVGPIIEKER NKNAAQELAT LLLSLPAPAS
2530 2540 2550 2560 2570 2580
VQQQSKSLLA SLHTSRSAYH SHKDQALLSK AVQCLNTSSK EGKDLDPEVF QRLVITARSI
2590 2600 2610 2620 2630 2640
AIMRPNNLVH FTESKLPQME TEGMDEGKEP QKQLEGDCCS FITQLVNHFW KLHASKPKNA
2650 2660 2670 2680 2690 2700
FLAPACLPGL THIEATVNAL VDIIHGYCTC ELDCINTASK IYMQMLLCPD PAVSFSCKQA
2710 2720 2730 2740 2750 2760
LIRVLRPRNK RRHVTLPSSP RSNTPMGDKD DDDDDDADEK MQSSGIPNGG HIRQESQEQS
2770 2780 2790 2800 2810 2820
EVDHGDFEMV SESMVLETAE NVNNGNPSPL EALLAGAEGF PPMLDIPPDA DDETMVELAI
2830 2840 2850 2860 2870 2880
ALSLQQDQQG SSSSALGLQS LGLSGQAPSS SSLDAGTLSD TTASAPASDD EGSTAATDGS
2890 2900 2910 2920 2930 2940
TLRTSPADHG GSVGSESGGS AVDSVAGEHS VSGRSSAYGD ATAEGHPAGP GSVSSSTGAI
2950 2960 2970 2980 2990 3000
STTTGHQEGD GSEGEGEGET EGDVHTSNRL HMVRLMLLER LLQTLPQLRN VGGVRAIPYM
3010 3020 3030 3040 3050 3060
QVILMLTTDL DGEDEKDKGA LDNLLSQLIA ELGMDKKDVS KKNERSALNE VHLVVMRLLS
3070 3080 3090 3100 3110 3120
VFMSRTKSGS KSSICESSSL ISSATAAALL SSGAVDYCLH VLKSLLEYWK SQQNDEEPVA
3130 3140 3150 3160 3170 3180
TSQLLKPHTT SSPPDMSPFF LRQYVKGHAA DVFEAYTQLL TEMVLRLPYQ IKKITDTNSR
3190 3200 3210 3220 3230 3240
IPPPVFDHSW FYFLSEYLMI QQTPFVRRQV RKLLLFICGS KEKYRQLRDL HTLDSHVRGI
3250 3260 3270 3280 3290 3300
KKLLEEQGIF LRASVVTASS GSALQYDTLI SLMEHLKACA EIAAQRTINW QKFCIKDDSV
3310 3320 3330 3340 3350 3360
LYFLLQVSFL VDEGVSPVLL QLLSCALCGS KVLAALAASS GSSSASSSSA PVAASSGQAT
3370 3380 3390 3400 3410 3420
TQSKSSTKKS KKEEKEKEKD GETSGSQEDQ LCTALVNQLN KFADKETLIQ FLRCFLLESN
3430 3440 3450 3460 3470 3480
SSSVRWQAHC LTLHIYRNSS KSQQELLLDL MWSIWPELPA YGRKAAQFVD LLGYFSLKTP
3490 3500 3510 3520 3530 3540
QTEKKLKEYS QKAVEILRTQ NHILTNHPNS NIYNTLSGLV EFDGYYLESD PCLVCNNPEV
3550 3560 3570 3580 3590 3600
PFCYIKLSSI KVDTRYTTTQ QVVKLIGSHT ISKVTVKIGD LKRTKMVRTI NLYYNNRTVQ
3610 3620 3630 3640 3650 3660
AIVELKNKPA RWHKAKKVQL TPGQTEVKID LPLPIVASNL MIEFADFYEN YQASTETLQC
3670 3680 3690 3700 3710 3720
PRCSASVPAN PGVCGNCGEN VYQCHKCRSI NYDEKDPFLC NACGFCKYAR FDFMLYAKPC
3730 3740 3750 3760 3770 3780
CAVDPIENEE DRKKAVSNIN TLLDKADRVY HQLMGHRPQL ENLLCKVNEA APEKPQDDSG
3790 3800 3810 3820 3830 3840
TAGGISSTSA SVNRYILQLA QEYCGDCKNS FDELSKIIQK VFASRKELLE YDLQQREAAT
3850 3860 3870 3880 3890 3900
KSSRTSVQPT FTASQYRALS VLGCGHTSST KCYGCASAVT EHCITLLRAL ATNPALRHIL
3910 3920 3930 3940 3950 3960
VSQGLIRELF DYNLRRGAAA MREEVRQLMC LLTRDNPEAT QQMNDLIIGK VSTALKGHWA
3970 3980 3990 4000 4010 4020
NPDLASSLQY EMLLLTDSIS KEDSCWELRL RCALSLFLMA VNIKTPVVVE NITLMCLRIL
4030 4040 4050 4060 4070 4080
QKLIKPPAPT SKKNKDVPVE ALTTVKPYCN EIHAQAQLWL KRDPKASYDA WKKCLPIRGI
4090 4100 4110 4120 4130 4140
DGNGKAPSKS ELRHLYLTEK YVWRWKQFLS RRGKRTSPLD LKLGHNNWLR QVLFTPATQA
4150 4160 4170 4180 4190 4200
ARQAACTIVE ALATIPSRKQ QVLDLLTSYL DELSIAGECA AEYLALYQKL ITSAHWKVYL
4210 4220 4230 4240 4250 4260
AARGVLPYVG NLITKEIARL LALEEATLST DLQQGYALKS LTGLLSSFVE VESIKRHFKS
4270 4280 4290 4300 4310 4320
RLVGTVLNGY LCLRKLVVQR TKLIDETQDM LLEMLEDMTT GTESETKAFM AVCIETAKRY
4330 4340 4350 4360 4370 4380
NLDDYRTPVF IFERLCSIIY PEENEVTEFF VTLEKDPQQE DFLQGRMPGN PYSSNEPGIG
4390 4400 4410 4420 4430 4440
PLMRDIKNKI CQDCDLVALL EDDSGMELLV NNKIISLDLP VAEVYKKVWC TTNEGEPMRI
4450 4460 4470 4480 4490 4500
VYRMRGLLGD ATEEFIESLD STTDEEEDEE EVYKMAGVMA QCGGLECMLN RLAGIRDFKQ
4510 4520 4530 4540 4550 4560
GRHLLTVLLK LFSYCVKVKV NRQQLVKLEM NTLNVMLGTL NLALVAEQES KDSGGAAVAE
4570 4580 4590 4600 4610 4620
QVLSIMEIIL DESNAEPLSE DKGNLLLTGD KDQLVMLLDQ INSTFVRSNP SVLQGLLRII
4630 4640 4650 4660 4670 4680
PYLSFGEVEK MQILVERFKP YCNFDKYDED HSGDDKVFLD CFCKIAAGIK NNSNGHQLKD
4690 4700 4710 4720 4730 4740
LILQKGITQN ALDYMKKHIP SAKNLDADIW KKFLSRPALP FILRLLRGLA IQHPGTQVLI
4750 4760 4770 4780 4790 4800
GTDSIPNLHK LEQVSSDEGI GTLAENLLEA LREHPDVNKK IDAARRETRA EKKRMAMAMR
4810 4820 4830 4840 4850 4860
QKALGTLGMT TNEKGQVVTK TALLKQMEEL IEEPGLTCCI CREGYKFQPT KVLGIYTFTK
4870 4880 4890 4900 4910 4920
RVALEEMENK PRKQQGYSTV SHFNIVHYDC HLAAVRLARG REEWESAALQ NANTKCNGLL
4930 4940 4950 4960 4970 4980
PVWGPHVPES AFATCLARHN TYLQECTGQR EPTYQLNIHD IKLLFLRFAM EQSFSADTGG
4990 5000 5010 5020 5030 5040
GGRESNIHLI PYIIHTVLYV LNTTRATSRE EKNLQGFLEQ PKEKWVESAF EVDGPYYFTV
5050 5060 5070 5080 5090 5100
LALHILPPEQ WRATRVEILR RLLVTSQARA VAPGGATRLT DKAVKDYSAY RSSLLFWALV
5110 5120 5130 5140 5150 5160
DLIYNMFKKV PTSNTEGGWS CSLAEYIRHN DMPIYEAADK ALKTFQEEFM PVETFSEFLD
5170 5180
VAGLLSEITD PESFLKDLLN SVP
10 20 30 40 50 60
MATSGGEEAA AAAPAPGTPA TGADTTPGWE VAVRPLLSAS YSAFEMKELP QLVASVIESE
70 80 90 100 110 120
SEILHHEKQY EPFYSSFVAL STHYITTVCS LIPRNQLQSV AAACKVLIEF SLLRLENPDE
130 140 150 160 170 180
ACAVSQKHLI LLIKGLCTGC SRLDRTEIIT FTAMMKSAKL PQTVKTLSDV EDQKELASPV
190 200 210 220 230 240
SPELRQKEVQ MNFLNQLTSV FNPRTVASQP ISTQTLVEGE NDEQSSTDQA SAIKTKNVFI
250 260 270 280 290 300
AQNVASLQEL GGSEKLLRVC LNLPYFLRYI NRFQDAVLAN SFFIMPATVA DATAVRNGFH
310 320 330 340 350 360
SLVIDVTMAL DTLSLPVLEP LNPSRLQDVT VLSLSCLYAG VSVATCMAIL HVGSAQQVRT
370 380 390 400 410 420
GSTSSKEDDY ESDAATIVQK CLEIYDMIGQ AISSSRRAGG EHYQNFQLLG AWCLLNSLFL
430 440 450 460 470 480
ILNLSPTALA DKGKEKDPLA ALRVRDILSR TKEGVGSPKL GPGKGHQGFG VLSVILANHA
490 500 510 520 530 540
IKLLTSLFQD LQVEALHKGW ETDGPPAALS IMAQSTSIQR IQRLIDSVPL MNLLLTLLST
550 560 570 580 590 600
SYRKACVLQR QRKGSMSSDA SASTDSNTYY EDDFSSTEED SSQDDDSEPI LGQWFEETIS
610 620 630 640 650 660
PSKEKAAPPP PPPPPPLESS PRVKSPSKQA PGEKGNILAS RKDPELFLGL ASNILNFITS
670 680 690 700 710 720
SMLNSRNNFI RNYLSVSLSE HHMATLASII KEVDKDGLKG SSDEEFAAAL YHFNHSLVTS
730 740 750 760 770 780
DLQSPNLQNT LLQQLGVAPF SEGPWPLYIH PQSLSVLSRL LLIWQHKASA QGDPDVPECL
790 800 810 820 830 840
KVWDRFLSTM KQNALQGVVP SETEDLNVEH LQMLLLIFHN FTETGRRAIL SLFVQIIQEL
850 860 870 880 890 900
SVNMDAQMRF VPLILARLLL IFDYLLHQYS KAPVYLFEQV QHNLLSPPFG WASGSQDSNS
910 920 930 940 950 960
RRATTPLYHG FKEVEENWSK HFSSDAVPHP RFYCVLSPEA SEDDLNRLDS VACDVLFSKL
970 980 990 1000 1010 1020
VKYDELYAAL TALLAAGSQL DTVRRKENKN VTALEACALQ YYFLILWRIL GILPPSKTYI
1030 1040 1050 1060 1070 1080
NQLSMNSPEM SECDILHTLR WSSRLRISSY VNWIKDHLIK QGMKAEHASS LLELASTTKC
1090 1100 1110 1120 1130 1140
SSVKYDVEIV EEYFARQISS FCSIDCTTIL QLHEIPSLQS IYTLDAAISK VQVSLDEHFS
1150 1160 1170 1180 1190 1200
KMAAETDPHK SSEITKNLLP ATLQLIDTYA SFTRAYLLQN FNEEGTTEKP SKEKLQGFAA
1210 1220 1230 1240 1250 1260
VLAIGSSRCK ANTLGPTLVQ NLPSSVQTVC ESWNNINTNE FPNIGSWRNA FANDTIPSES
1270 1280 1290 1300 1310 1320
YISAVQAAHL GTLCSQSLPL AASLKHTLLS LVRLTGDLIV WSDEMNPPQV IRTLLPLLLE
1330 1340 1350 1360 1370 1380
SSTESVAEIS SNSLERILGP AESDEFLARV YEKLITGCYN ILANHADPNS GLDESILEEC
1390 1400 1410 1420 1430 1440
LQYLEKQLES SQARKAMEEF FSDSGELVQI MMATANENLS AKFCNRVLKF FTKLFQLTEK
1450 1460 1470 1480 1490 1500
SPNPSLLHLC GSLAQLACVE PVRLQAWLTR MTTSPPKDSD QLDVIQENRQ LLQLLTTYIV
1510 1520 1530 1540 1550 1560
RENSQVGEGV CAVLLGTLTP MATEMLANGD GTGFPELMVV MATLASAGQG AGHLQLHNAA
1570 1580 1590 1600 1610 1620
VDWLSRCKKY LSQKNVVEKL NANVMHGKHV MILECTCHIM SYLADVTNAL SQSNGQGPSH
1630 1640 1650 1660 1670 1680
LSVDGEERAI EVDSDWVEEL AVEEEDSQAE DSDEDSLCNK LCTFTITQKE FMNQHWYHCH
1690 1700 1710 1720 1730 1740
TCKMVDGVGV CTVCAKVCHK DHEISYAKYG SFFCDCGAKE DGSCLALVKR TPSSGMSSTM
1750 1760 1770 1780 1790 1800
KESAFQSEPR ISESLVRHAS TSSPADKAKV TISDGKVADE EKPKKSSLCR TVEGCREELQ
1810 1820 1830 1840 1850 1860
NQANFSFAPL VLDMLNFLMD AIQTNFQQAS AVGSSSRAQQ ALSELHTVEK AVEMTDQLMV
1870 1880 1890 1900 1910 1920
PTLGSQEGAF ENVRMNYSGD QGQTIRQLIS AHVLRRVAMC VLSSPHGRRQ HLAVSHEKGK
1930 1940 1950 1960 1970 1980
ITVLQLSALL KQADSSKRKL TLTRLASAPV PFTVLSLTGN PCKEDYLAVC GLKDCHVLTF
1990 2000 2010 2020 2030 2040
SSSGSVSDHL VLHPQLATGN FIIKAVWLPG SQTELAIVTA DFVKIYDLCV DALSPTFYFL
2050 2060 2070 2080 2090 2100
LPSSKIRDVT FLFNEEGKNI IVIMSSAGYI YTQLMEEASS AQQGPFYVTN VLEINHEDLK
2110 2120 2130 2140 2150 2160
DSNSQVAGGG VSVYYSHVLQ MLFFSYCQGK SFAATISRTT LEVLQLFPIN IKSSNGGSKT
2170 2180 2190 2200 2210 2220
SPALCQWSEV MNHPGLVCCV QQTTGVPLVV MVKPDTFLIQ EIKTLPAKAK IQDMVAIRHT
2230 2240 2250 2260 2270 2280
ACNEQQRTTM ILLCEDGSLR IYMANVENTS YWLQPSLQPS SVISIMKPVR KRKTATITTR
2290 2300 2310 2320 2330 2340
TSSQVTFPID FFEHNQQLTD VEFGGNDLLQ VYNAQQIKHR LNSTGMYVAN TKPGGFTIEI
2350 2360 2370 2380 2390 2400
SNNNSTMVMT GMRIQIGTQA IERAPSYIEI FGRTMQLNLS RSRWFDFPFT REEALQADKK
2410 2420 2430 2440 2450 2460
LNLFIGASVD PAGVTMIDAV KIYGKTKEQF GWPDEPPEEF PSASVSNICP SNLNQSNGTG
2470 2480 2490 2500 2510 2520
DSDSAAPTTT SGTVLERLVV SSLEALESCF AVGPIIEKER NKNAAQELAT LLLSLPAPAS
2530 2540 2550 2560 2570 2580
VQQQSKSLLA SLHTSRSAYH SHKDQALLSK AVQCLNTSSK EGKDLDPEVF QRLVITARSI
2590 2600 2610 2620 2630 2640
AIMRPNNLVH FTESKLPQME TEGMDEGKEP QKQLEGDCCS FITQLVNHFW KLHASKPKNA
2650 2660 2670 2680 2690 2700
FLAPACLPGL THIEATVNAL VDIIHGYCTC ELDCINTASK IYMQMLLCPD PAVSFSCKQA
2710 2720 2730 2740 2750 2760
LIRVLRPRNK RRHVTLPSSP RSNTPMGDKD DDDDDDADEK MQSSGIPNGG HIRQESQEQS
2770 2780 2790 2800 2810 2820
EVDHGDFEMV SESMVLETAE NVNNGNPSPL EALLAGAEGF PPMLDIPPDA DDETMVELAI
2830 2840 2850 2860 2870 2880
ALSLQQDQQG SSSSALGLQS LGLSGQAPSS SSLDAGTLSD TTASAPASDD EGSTAATDGS
2890 2900 2910 2920 2930 2940
TLRTSPADHG GSVGSESGGS AVDSVAGEHS VSGRSSAYGD ATAEGHPAGP GSVSSSTGAI
2950 2960 2970 2980 2990 3000
STTTGHQEGD GSEGEGEGET EGDVHTSNRL HMVRLMLLER LLQTLPQLRN VGGVRAIPYM
3010 3020 3030 3040 3050 3060
QVILMLTTDL DGEDEKDKGA LDNLLSQLIA ELGMDKKDVS KKNERSALNE VHLVVMRLLS
3070 3080 3090 3100 3110 3120
VFMSRTKSGS KSSICESSSL ISSATAAALL SSGAVDYCLH VLKSLLEYWK SQQNDEEPVA
3130 3140 3150 3160 3170 3180
TSQLLKPHTT SSPPDMSPFF LRQYVKGHAA DVFEAYTQLL TEMVLRLPYQ IKKITDTNSR
3190 3200 3210 3220 3230 3240
IPPPVFDHSW FYFLSEYLMI QQTPFVRRQV RKLLLFICGS KEKYRQLRDL HTLDSHVRGI
3250 3260 3270 3280 3290 3300
KKLLEEQGIF LRASVVTASS GSALQYDTLI SLMEHLKACA EIAAQRTINW QKFCIKDDSV
3310 3320 3330 3340 3350 3360
LYFLLQVSFL VDEGVSPVLL QLLSCALCGS KVLAALAASS GSSSASSSSA PVAASSGQAT
3370 3380 3390 3400 3410 3420
TQSKSSTKKS KKEEKEKEKD GETSGSQEDQ LCTALVNQLN KFADKETLIQ FLRCFLLESN
3430 3440 3450 3460 3470 3480
SSSVRWQAHC LTLHIYRNSS KSQQELLLDL MWSIWPELPA YGRKAAQFVD LLGYFSLKTP
3490 3500 3510 3520 3530 3540
QTEKKLKEYS QKAVEILRTQ NHILTNHPNS NIYNTLSGLV EFDGYYLESD PCLVCNNPEV
3550 3560 3570 3580 3590 3600
PFCYIKLSSI KVDTRYTTTQ QVVKLIGSHT ISKVTVKIGD LKRTKMVRTI NLYYNNRTVQ
3610 3620 3630 3640 3650 3660
AIVELKNKPA RWHKAKKVQL TPGQTEVKID LPLPIVASNL MIEFADFYEN YQASTETLQC
3670 3680 3690 3700 3710 3720
PRCSASVPAN PGVCGNCGEN VYQCHKCRSI NYDEKDPFLC NACGFCKYAR FDFMLYAKPC
3730 3740 3750 3760 3770 3780
CAVDPIENEE DRKKAVSNIN TLLDKADRVY HQLMGHRPQL ENLLCKVNEA APEKPQDDSG
3790 3800 3810 3820 3830 3840
TAGGISSTSA SVNRYILQLA QEYCGDCKNS FDELSKIIQK VFASRKELLE YDLQQREAAT
3850 3860 3870 3880 3890 3900
KSSRTSVQPT FTASQYRALS VLGCGHTSST KCYGCASAVT EHCITLLRAL ATNPALRHIL
3910 3920 3930 3940 3950 3960
VSQGLIRELF DYNLRRGAAA MREEVRQLMC LLTRDNPEAT QQMNDLIIGK VSTALKGHWA
3970 3980 3990 4000 4010 4020
NPDLASSLQY EMLLLTDSIS KEDSCWELRL RCALSLFLMA VNIKTPVVVE NITLMCLRIL
4030 4040 4050 4060 4070 4080
QKLIKPPAPT SKKNKDVPVE ALTTVKPYCN EIHAQAQLWL KRDPKASYDA WKKCLPIRGI
4090 4100 4110 4120 4130 4140
DGNGKAPSKS ELRHLYLTEK YVWRWKQFLS RRGKRTSPLD LKLGHNNWLR QVLFTPATQA
4150 4160 4170 4180 4190 4200
ARQAACTIVE ALATIPSRKQ QVLDLLTSYL DELSIAGECA AEYLALYQKL ITSAHWKVYL
4210 4220 4230 4240 4250 4260
AARGVLPYVG NLITKEIARL LALEEATLST DLQQGYALKS LTGLLSSFVE VESIKRHFKS
4270 4280 4290 4300 4310 4320
RLVGTVLNGY LCLRKLVVQR TKLIDETQDM LLEMLEDMTT GTESETKAFM AVCIETAKRY
4330 4340 4350 4360 4370 4380
NLDDYRTPVF IFERLCSIIY PEENEVTEFF VTLEKDPQQE DFLQGRMPGN PYSSNEPGIG
4390 4400 4410 4420 4430 4440
PLMRDIKNKI CQDCDLVALL EDDSGMELLV NNKIISLDLP VAEVYKKVWC TTNEGEPMRI
4450 4460 4470 4480 4490 4500
VYRMRGLLGD ATEEFIESLD STTDEEEDEE EVYKMAGVMA QCGGLECMLN RLAGIRDFKQ
4510 4520 4530 4540 4550 4560
GRHLLTVLLK LFSYCVKVKV NRQQLVKLEM NTLNVMLGTL NLALVAEQES KDSGGAAVAE
4570 4580 4590 4600 4610 4620
QVLSIMEIIL DESNAEPLSE DKGNLLLTGD KDQLVMLLDQ INSTFVRSNP SVLQGLLRII
4630 4640 4650 4660 4670 4680
PYLSFGEVEK MQILVERFKP YCNFDKYDED HSGDDKVFLD CFCKIAAGIK NNSNGHQLKD
4690 4700 4710 4720 4730 4740
LILQKGITQN ALDYMKKHIP SAKNLDADIW KKFLSRPALP FILRLLRGLA IQHPGTQVLI
4750 4760 4770 4780 4790 4800
GTDSIPNLHK LEQVSSDEGI GTLAENLLEA LREHPDVNKK IDAARRETRA EKKRMAMAMR
4810 4820 4830 4840 4850 4860
QKALGTLGMT TNEKGQVVTK TALLKQMEEL IEEPGLTCCI CREGYKFQPT KVLGIYTFTK
4870 4880 4890 4900 4910 4920
RVALEEMENK PRKQQGYSTV SHFNIVHYDC HLAAVRLARG REEWESAALQ NANTKCNGLL
4930 4940 4950 4960 4970 4980
PVWGPHVPES AFATCLARHN TYLQECTGQR EPTYQLNIHD IKLLFLRFAM EQSFSADTGG
4990 5000 5010 5020 5030 5040
GGRESNIHLI PYIIHTVLYV LNTTRATSRE EKNLQGFLEQ PKEKWVESAF EVDGPYYFTV
5050 5060 5070 5080 5090 5100
LALHILPPEQ WRATRVEILR RLLVTSQARA VAPGGATRLT DKAVKDYSAY RSSLLFWALV
5110 5120 5130 5140 5150 5160
DLIYNMFKKV PTSNTEGGWS CSLAEYIRHN DMPIYEAADK ALKTFQEEFM PVETFSEFLD
5170 5180
VAGLLSEITD PESFLKDLLN SVP
10 20 30 40 50 60
MATSGGEEAA AAAPAPGTPA TGADTTPGWE VAVRPLLSAS YSAFEMKELP QLVASVIESE
70 80 90 100 110 120
SEILHHEKQY EPFYSSFVAL STHYITTVCS LIPRNQLQSV AAACKVLIEF SLLRLENPDE
130 140 150 160 170 180
ACAVSQKHLI LLIKGLCTGC SRLDRTEIIT FTAMMKSAKL PQTVKTLSDV EDQKELASPV
190 200 210 220 230 240
SPELRQKEVQ MNFLNQLTSV FNPRTVASQP ISTQTLVEGE NDEQSSTDQA SAIKTKNVFI
250 260 270 280 290 300
AQNVASLQEL GGSEKLLRVC LNLPYFLRYI NRFQDAVLAN SFFIMPATVA DATAVRNGFH
310 320 330 340 350 360
SLVIDVTMAL DTLSLPVLEP LNPSRLQDVT VLSLSCLYAG VSVATCMAIL HVGSAQQVRT
370 380 390 400 410 420
GSTSSKEDDY ESDAATIVQK CLEIYDMIGQ AISSSRRAGG EHYQNFQLLG AWCLLNSLFL
430 440 450 460 470 480
ILNLSPTALA DKGKEKDPLA ALRVRDILSR TKEGVGSPKL GPGKGHQGFG VLSVILANHA
490 500 510 520 530 540
IKLLTSLFQD LQVEALHKGW ETDGPPAALS IMAQSTSIQR IQRLIDSVPL MNLLLTLLST
550 560 570 580 590 600
SYRKACVLQR QRKGSMSSDA SASTDSNTYY EDDFSSTEED SSQDDDSEPI LGQWFEETIS
610 620 630 640 650 660
PSKEKAAPPP PPPPPPLESS PRVKSPSKQA PGEKGNILAS RKDPELFLGL ASNILNFITS
670 680 690 700 710 720
SMLNSRNNFI RNYLSVSLSE HHMATLASII KEVDKDGLKG SSDEEFAAAL YHFNHSLVTS
730 740 750 760 770 780
DLQSPNLQNT LLQQLGVAPF SEGPWPLYIH PQSLSVLSRL LLIWQHKASA QGDPDVPECL
790 800 810 820 830 840
KVWDRFLSTM KQNALQGVVP SETEDLNVEH LQMLLLIFHN FTETGRRAIL SLFVQIIQEL
850 860 870 880 890 900
SVNMDAQMRF VPLILARLLL IFDYLLHQYS KAPVYLFEQV QHNLLSPPFG WASGSQDSNS
910 920 930 940 950 960
RRATTPLYHG FKEVEENWSK HFSSDAVPHP RFYCVLSPEA SEDDLNRLDS VACDVLFSKL
970 980 990 1000 1010 1020
VKYDELYAAL TALLAAGSQL DTVRRKENKN VTALEACALQ YYFLILWRIL GILPPSKTYI
1030 1040 1050 1060 1070 1080
NQLSMNSPEM SECDILHTLR WSSRLRISSY VNWIKDHLIK QGMKAEHASS LLELASTTKC
1090 1100 1110 1120 1130 1140
SSVKYDVEIV EEYFARQISS FCSIDCTTIL QLHEIPSLQS IYTLDAAISK VQVSLDEHFS
1150 1160 1170 1180 1190 1200
KMAAETDPHK SSEITKNLLP ATLQLIDTYA SFTRAYLLQN FNEEGTTEKP SKEKLQGFAA
1210 1220 1230 1240 1250 1260
VLAIGSSRCK ANTLGPTLVQ NLPSSVQTVC ESWNNINTNE FPNIGSWRNA FANDTIPSES
1270 1280 1290 1300 1310 1320
YISAVQAAHL GTLCSQSLPL AASLKHTLLS LVRLTGDLIV WSDEMNPPQV IRTLLPLLLE
1330 1340 1350 1360 1370 1380
SSTESVAEIS SNSLERILGP AESDEFLARV YEKLITGCYN ILANHADPNS GLDESILEEC
1390 1400 1410 1420 1430 1440
LQYLEKQLES SQARKAMEEF FSDSGELVQI MMATANENLS AKFCNRVLKF FTKLFQLTEK
1450 1460 1470 1480 1490 1500
SPNPSLLHLC GSLAQLACVE PVRLQAWLTR MTTSPPKDSD QLDVIQENRQ LLQLLTTYIV
1510 1520 1530 1540 1550 1560
RENSQVGEGV CAVLLGTLTP MATEMLANGD GTGFPELMVV MATLASAGQG AGHLQLHNAA
1570 1580 1590 1600 1610 1620
VDWLSRCKKY LSQKNVVEKL NANVMHGKHV MILECTCHIM SYLADVTNAL SQSNGQGPSH
1630 1640 1650 1660 1670 1680
LSVDGEERAI EVDSDWVEEL AVEEEDSQAE DSDEDSLCNK LCTFTITQKE FMNQHWYHCH
1690 1700 1710 1720 1730 1740
TCKMVDGVGV CTVCAKVCHK DHEISYAKYG SFFCDCGAKE DGSCLALVKR TPSSGMSSTM
1750 1760 1770 1780 1790 1800
KESAFQSEPR ISESLVRHAS TSSPADKAKV TISDGKVADE EKPKKSSLCR TVEGCREELQ
1810 1820 1830 1840 1850 1860
NQANFSFAPL VLDMLNFLMD AIQTNFQQAS AVGSSSRAQQ ALSELHTVEK AVEMTDQLMV
1870 1880 1890 1900 1910 1920
PTLGSQEGAF ENVRMNYSGD QGQTIRQLIS AHVLRRVAMC VLSSPHGRRQ HLAVSHEKGK
1930 1940 1950 1960 1970 1980
ITVLQLSALL KQADSSKRKL TLTRLASAPV PFTVLSLTGN PCKEDYLAVC GLKDCHVLTF
1990 2000 2010 2020 2030 2040
SSSGSVSDHL VLHPQLATGN FIIKAVWLPG SQTELAIVTA DFVKIYDLCV DALSPTFYFL
2050 2060 2070 2080 2090 2100
LPSSKIRDVT FLFNEEGKNI IVIMSSAGYI YTQLMEEASS AQQGPFYVTN VLEINHEDLK
2110 2120 2130 2140 2150 2160
DSNSQVAGGG VSVYYSHVLQ MLFFSYCQGK SFAATISRTT LEVLQLFPIN IKSSNGGSKT
2170 2180 2190 2200 2210 2220
SPALCQWSEV MNHPGLVCCV QQTTGVPLVV MVKPDTFLIQ EIKTLPAKAK IQDMVAIRHT
2230 2240 2250 2260 2270 2280
ACNEQQRTTM ILLCEDGSLR IYMANVENTS YWLQPSLQPS SVISIMKPVR KRKTATITTR
2290 2300 2310 2320 2330 2340
TSSQVTFPID FFEHNQQLTD VEFGGNDLLQ VYNAQQIKHR LNSTGMYVAN TKPGGFTIEI
2350 2360 2370 2380 2390 2400
SNNNSTMVMT GMRIQIGTQA IERAPSYIEI FGRTMQLNLS RSRWFDFPFT REEALQADKK
2410 2420 2430 2440 2450 2460
LNLFIGASVD PAGVTMIDAV KIYGKTKEQF GWPDEPPEEF PSASVSNICP SNLNQSNGTG
2470 2480 2490 2500 2510 2520
DSDSAAPTTT SGTVLERLVV SSLEALESCF AVGPIIEKER NKNAAQELAT LLLSLPAPAS
2530 2540 2550 2560 2570 2580
VQQQSKSLLA SLHTSRSAYH SHKDQALLSK AVQCLNTSSK EGKDLDPEVF QRLVITARSI
2590 2600 2610 2620 2630 2640
AIMRPNNLVH FTESKLPQME TEGMDEGKEP QKQLEGDCCS FITQLVNHFW KLHASKPKNA
2650 2660 2670 2680 2690 2700
FLAPACLPGL THIEATVNAL VDIIHGYCTC ELDCINTASK IYMQMLLCPD PAVSFSCKQA
2710 2720 2730 2740 2750 2760
LIRVLRPRNK RRHVTLPSSP RSNTPMGDKD DDDDDDADEK MQSSGIPNGG HIRQESQEQS
2770 2780 2790 2800 2810 2820
EVDHGDFEMV SESMVLETAE NVNNGNPSPL EALLAGAEGF PPMLDIPPDA DDETMVELAI
2830 2840 2850 2860 2870 2880
ALSLQQDQQG SSSSALGLQS LGLSGQAPSS SSLDAGTLSD TTASAPASDD EGSTAATDGS
2890 2900 2910 2920 2930 2940
TLRTSPADHG GSVGSESGGS AVDSVAGEHS VSGRSSAYGD ATAEGHPAGP GSVSSSTGAI
2950 2960 2970 2980 2990 3000
STTTGHQEGD GSEGEGEGET EGDVHTSNRL HMVRLMLLER LLQTLPQLRN VGGVRAIPYM
3010 3020 3030 3040 3050 3060
QVILMLTTDL DGEDEKDKGA LDNLLSQLIA ELGMDKKDVS KKNERSALNE VHLVVMRLLS
3070 3080 3090 3100 3110 3120
VFMSRTKSGS KSSICESSSL ISSATAAALL SSGAVDYCLH VLKSLLEYWK SQQNDEEPVA
3130 3140 3150 3160 3170 3180
TSQLLKPHTT SSPPDMSPFF LRQYVKGHAA DVFEAYTQLL TEMVLRLPYQ IKKITDTNSR
3190 3200 3210 3220 3230 3240
IPPPVFDHSW FYFLSEYLMI QQTPFVRRQV RKLLLFICGS KEKYRQLRDL HTLDSHVRGI
3250 3260 3270 3280 3290 3300
KKLLEEQGIF LRASVVTASS GSALQYDTLI SLMEHLKACA EIAAQRTINW QKFCIKDDSV
3310 3320 3330 3340 3350 3360
LYFLLQVSFL VDEGVSPVLL QLLSCALCGS KVLAALAASS GSSSASSSSA PVAASSGQAT
3370 3380 3390 3400 3410 3420
TQSKSSTKKS KKEEKEKEKD GETSGSQEDQ LCTALVNQLN KFADKETLIQ FLRCFLLESN
3430 3440 3450 3460 3470 3480
SSSVRWQAHC LTLHIYRNSS KSQQELLLDL MWSIWPELPA YGRKAAQFVD LLGYFSLKTP
3490 3500 3510 3520 3530 3540
QTEKKLKEYS QKAVEILRTQ NHILTNHPNS NIYNTLSGLV EFDGYYLESD PCLVCNNPEV
3550 3560 3570 3580 3590 3600
PFCYIKLSSI KVDTRYTTTQ QVVKLIGSHT ISKVTVKIGD LKRTKMVRTI NLYYNNRTVQ
3610 3620 3630 3640 3650 3660
AIVELKNKPA RWHKAKKVQL TPGQTEVKID LPLPIVASNL MIEFADFYEN YQASTETLQC
3670 3680 3690 3700 3710 3720
PRCSASVPAN PGVCGNCGEN VYQCHKCRSI NYDEKDPFLC NACGFCKYAR FDFMLYAKPC
3730 3740 3750 3760 3770 3780
CAVDPIENEE DRKKAVSNIN TLLDKADRVY HQLMGHRPQL ENLLCKVNEA APEKPQDDSG
3790 3800 3810 3820 3830 3840
TAGGISSTSA SVNRYILQLA QEYCGDCKNS FDELSKIIQK VFASRKELLE YDLQQREAAT
3850 3860 3870 3880 3890 3900
KSSRTSVQPT FTASQYRALS VLGCGHTSST KCYGCASAVT EHCITLLRAL ATNPALRHIL
3910 3920 3930 3940 3950 3960
VSQGLIRELF DYNLRRGAAA MREEVRQLMC LLTRDNPEAT QQMNDLIIGK VSTALKGHWA
3970 3980 3990 4000 4010 4020
NPDLASSLQY EMLLLTDSIS KEDSCWELRL RCALSLFLMA VNIKTPVVVE NITLMCLRIL
4030 4040 4050 4060 4070 4080
QKLIKPPAPT SKKNKDVPVE ALTTVKPYCN EIHAQAQLWL KRDPKASYDA WKKCLPIRGI
4090 4100 4110 4120 4130 4140
DGNGKAPSKS ELRHLYLTEK YVWRWKQFLS RRGKRTSPLD LKLGHNNWLR QVLFTPATQA
4150 4160 4170 4180 4190 4200
ARQAACTIVE ALATIPSRKQ QVLDLLTSYL DELSIAGECA AEYLALYQKL ITSAHWKVYL
4210 4220 4230 4240 4250 4260
AARGVLPYVG NLITKEIARL LALEEATLST DLQQGYALKS LTGLLSSFVE VESIKRHFKS
4270 4280 4290 4300 4310 4320
RLVGTVLNGY LCLRKLVVQR TKLIDETQDM LLEMLEDMTT GTESETKAFM AVCIETAKRY
4330 4340 4350 4360 4370 4380
NLDDYRTPVF IFERLCSIIY PEENEVTEFF VTLEKDPQQE DFLQGRMPGN PYSSNEPGIG
4390 4400 4410 4420 4430 4440
PLMRDIKNKI CQDCDLVALL EDDSGMELLV NNKIISLDLP VAEVYKKVWC TTNEGEPMRI
4450 4460 4470 4480 4490 4500
VYRMRGLLGD ATEEFIESLD STTDEEEDEE EVYKMAGVMA QCGGLECMLN RLAGIRDFKQ
4510 4520 4530 4540 4550 4560
GRHLLTVLLK LFSYCVKVKV NRQQLVKLEM NTLNVMLGTL NLALVAEQES KDSGGAAVAE
4570 4580 4590 4600 4610 4620
QVLSIMEIIL DESNAEPLSE DKGNLLLTGD KDQLVMLLDQ INSTFVRSNP SVLQGLLRII
4630 4640 4650 4660 4670 4680
PYLSFGEVEK MQILVERFKP YCNFDKYDED HSGDDKVFLD CFCKIAAGIK NNSNGHQLKD
4690 4700 4710 4720 4730 4740
LILQKGITQN ALDYMKKHIP SAKNLDADIW KKFLSRPALP FILRLLRGLA IQHPGTQVLI
4750 4760 4770 4780 4790 4800
GTDSIPNLHK LEQVSSDEGI GTLAENLLEA LREHPDVNKK IDAARRETRA EKKRMAMAMR
4810 4820 4830 4840 4850 4860
QKALGTLGMT TNEKGQVVTK TALLKQMEEL IEEPGLTCCI CREGYKFQPT KVLGIYTFTK
4870 4880 4890 4900 4910 4920
RVALEEMENK PRKQQGYSTV SHFNIVHYDC HLAAVRLARG REEWESAALQ NANTKCNGLL
4930 4940 4950 4960 4970 4980
PVWGPHVPES AFATCLARHN TYLQECTGQR EPTYQLNIHD IKLLFLRFAM EQSFSADTGG
4990 5000 5010 5020 5030 5040
GGRESNIHLI PYIIHTVLYV LNTTRATSRE EKNLQGFLEQ PKEKWVESAF EVDGPYYFTV
5050 5060 5070 5080 5090 5100
LALHILPPEQ WRATRVEILR RLLVTSQARA VAPGGATRLT DKAVKDYSAY RSSLLFWALV
5110 5120 5130 5140 5150 5160
DLIYNMFKKV PTSNTEGGWS CSLAEYIRHN DMPIYEAADK ALKTFQEEFM PVETFSEFLD
5170 5180
VAGLLSEITD PESFLKDLLN SVP
10 20 30 40 50 60
MATSGGEEAA AAAPAPGTPA TGADTTPGWE VAVRPLLSAS YSAFEMKELP QLVASVIESE
70 80 90 100 110 120
SEILHHEKQY EPFYSSFVAL STHYITTVCS LIPRNQLQSV AAACKVLIEF SLLRLENPDE
130 140 150 160 170 180
ACAVSQKHLI LLIKGLCTGC SRLDRTEIIT FTAMMKSAKL PQTVKTLSDV EDQKELASPV
190 200 210 220 230 240
SPELRQKEVQ MNFLNQLTSV FNPRTVASQP ISTQTLVEGE NDEQSSTDQA SAIKTKNVFI
250 260 270 280 290 300
AQNVASLQEL GGSEKLLRVC LNLPYFLRYI NRFQDAVLAN SFFIMPATVA DATAVRNGFH
310 320 330 340 350 360
SLVIDVTMAL DTLSLPVLEP LNPSRLQDVT VLSLSCLYAG VSVATCMAIL HVGSAQQVRT
370 380 390 400 410 420
GSTSSKEDDY ESDAATIVQK CLEIYDMIGQ AISSSRRAGG EHYQNFQLLG AWCLLNSLFL
430 440 450 460 470 480
ILNLSPTALA DKGKEKDPLA ALRVRDILSR TKEGVGSPKL GPGKGHQGFG VLSVILANHA
490 500 510 520 530 540
IKLLTSLFQD LQVEALHKGW ETDGPPAALS IMAQSTSIQR IQRLIDSVPL MNLLLTLLST
550 560 570 580 590 600
SYRKACVLQR QRKGSMSSDA SASTDSNTYY EDDFSSTEED SSQDDDSEPI LGQWFEETIS
610 620 630 640 650 660
PSKEKAAPPP PPPPPPLESS PRVKSPSKQA PGEKGNILAS RKDPELFLGL ASNILNFITS
670 680 690 700 710 720
SMLNSRNNFI RNYLSVSLSE HHMATLASII KEVDKDGLKG SSDEEFAAAL YHFNHSLVTS
730 740 750 760 770 780
DLQSPNLQNT LLQQLGVAPF SEGPWPLYIH PQSLSVLSRL LLIWQHKASA QGDPDVPECL
790 800 810 820 830 840
KVWDRFLSTM KQNALQGVVP SETEDLNVEH LQMLLLIFHN FTETGRRAIL SLFVQIIQEL
850 860 870 880 890 900
SVNMDAQMRF VPLILARLLL IFDYLLHQYS KAPVYLFEQV QHNLLSPPFG WASGSQDSNS
910 920 930 940 950 960
RRATTPLYHG FKEVEENWSK HFSSDAVPHP RFYCVLSPEA SEDDLNRLDS VACDVLFSKL
970 980 990 1000 1010 1020
VKYDELYAAL TALLAAGSQL DTVRRKENKN VTALEACALQ YYFLILWRIL GILPPSKTYI
1030 1040 1050 1060 1070 1080
NQLSMNSPEM SECDILHTLR WSSRLRISSY VNWIKDHLIK QGMKAEHASS LLELASTTKC
1090 1100 1110 1120 1130 1140
SSVKYDVEIV EEYFARQISS FCSIDCTTIL QLHEIPSLQS IYTLDAAISK VQVSLDEHFS
1150 1160 1170 1180 1190 1200
KMAAETDPHK SSEITKNLLP ATLQLIDTYA SFTRAYLLQN FNEEGTTEKP SKEKLQGFAA
1210 1220 1230 1240 1250 1260
VLAIGSSRCK ANTLGPTLVQ NLPSSVQTVC ESWNNINTNE FPNIGSWRNA FANDTIPSES
1270 1280 1290 1300 1310 1320
YISAVQAAHL GTLCSQSLPL AASLKHTLLS LVRLTGDLIV WSDEMNPPQV IRTLLPLLLE
1330 1340 1350 1360 1370 1380
SSTESVAEIS SNSLERILGP AESDEFLARV YEKLITGCYN ILANHADPNS GLDESILEEC
1390 1400 1410 1420 1430 1440
LQYLEKQLES SQARKAMEEF FSDSGELVQI MMATANENLS AKFCNRVLKF FTKLFQLTEK
1450 1460 1470 1480 1490 1500
SPNPSLLHLC GSLAQLACVE PVRLQAWLTR MTTSPPKDSD QLDVIQENRQ LLQLLTTYIV
1510 1520 1530 1540 1550 1560
RENSQVGEGV CAVLLGTLTP MATEMLANGD GTGFPELMVV MATLASAGQG AGHLQLHNAA
1570 1580 1590 1600 1610 1620
VDWLSRCKKY LSQKNVVEKL NANVMHGKHV MILECTCHIM SYLADVTNAL SQSNGQGPSH
1630 1640 1650 1660 1670 1680
LSVDGEERAI EVDSDWVEEL AVEEEDSQAE DSDEDSLCNK LCTFTITQKE FMNQHWYHCH
1690 1700 1710 1720 1730 1740
TCKMVDGVGV CTVCAKVCHK DHEISYAKYG SFFCDCGAKE DGSCLALVKR TPSSGMSSTM
1750 1760 1770 1780 1790 1800
KESAFQSEPR ISESLVRHAS TSSPADKAKV TISDGKVADE EKPKKSSLCR TVEGCREELQ
1810 1820 1830 1840 1850 1860
NQANFSFAPL VLDMLNFLMD AIQTNFQQAS AVGSSSRAQQ ALSELHTVEK AVEMTDQLMV
1870 1880 1890 1900 1910 1920
PTLGSQEGAF ENVRMNYSGD QGQTIRQLIS AHVLRRVAMC VLSSPHGRRQ HLAVSHEKGK
1930 1940 1950 1960 1970 1980
ITVLQLSALL KQADSSKRKL TLTRLASAPV PFTVLSLTGN PCKEDYLAVC GLKDCHVLTF
1990 2000 2010 2020 2030 2040
SSSGSVSDHL VLHPQLATGN FIIKAVWLPG SQTELAIVTA DFVKIYDLCV DALSPTFYFL
2050 2060 2070 2080 2090 2100
LPSSKIRDVT FLFNEEGKNI IVIMSSAGYI YTQLMEEASS AQQGPFYVTN VLEINHEDLK
2110 2120 2130 2140 2150 2160
DSNSQVAGGG VSVYYSHVLQ MLFFSYCQGK SFAATISRTT LEVLQLFPIN IKSSNGGSKT
2170 2180 2190 2200 2210 2220
SPALCQWSEV MNHPGLVCCV QQTTGVPLVV MVKPDTFLIQ EIKTLPAKAK IQDMVAIRHT
2230 2240 2250 2260 2270 2280
ACNEQQRTTM ILLCEDGSLR IYMANVENTS YWLQPSLQPS SVISIMKPVR KRKTATITTR
2290 2300 2310 2320 2330 2340
TSSQVTFPID FFEHNQQLTD VEFGGNDLLQ VYNAQQIKHR LNSTGMYVAN TKPGGFTIEI
2350 2360 2370 2380 2390 2400
SNNNSTMVMT GMRIQIGTQA IERAPSYIEI FGRTMQLNLS RSRWFDFPFT REEALQADKK
2410 2420 2430 2440 2450 2460
LNLFIGASVD PAGVTMIDAV KIYGKTKEQF GWPDEPPEEF PSASVSNICP SNLNQSNGTG
2470 2480 2490 2500 2510 2520
DSDSAAPTTT SGTVLERLVV SSLEALESCF AVGPIIEKER NKNAAQELAT LLLSLPAPAS
2530 2540 2550 2560 2570 2580
VQQQSKSLLA SLHTSRSAYH SHKDQALLSK AVQCLNTSSK EGKDLDPEVF QRLVITARSI
2590 2600 2610 2620 2630 2640
AIMRPNNLVH FTESKLPQME TEGMDEGKEP QKQLEGDCCS FITQLVNHFW KLHASKPKNA
2650 2660 2670 2680 2690 2700
FLAPACLPGL THIEATVNAL VDIIHGYCTC ELDCINTASK IYMQMLLCPD PAVSFSCKQA
2710 2720 2730 2740 2750 2760
LIRVLRPRNK RRHVTLPSSP RSNTPMGDKD DDDDDDADEK MQSSGIPNGG HIRQESQEQS
2770 2780 2790 2800 2810 2820
EVDHGDFEMV SESMVLETAE NVNNGNPSPL EALLAGAEGF PPMLDIPPDA DDETMVELAI
2830 2840 2850 2860 2870 2880
ALSLQQDQQG SSSSALGLQS LGLSGQAPSS SSLDAGTLSD TTASAPASDD EGSTAATDGS
2890 2900 2910 2920 2930 2940
TLRTSPADHG GSVGSESGGS AVDSVAGEHS VSGRSSAYGD ATAEGHPAGP GSVSSSTGAI
2950 2960 2970 2980 2990 3000
STTTGHQEGD GSEGEGEGET EGDVHTSNRL HMVRLMLLER LLQTLPQLRN VGGVRAIPYM
3010 3020 3030 3040 3050 3060
QVILMLTTDL DGEDEKDKGA LDNLLSQLIA ELGMDKKDVS KKNERSALNE VHLVVMRLLS
3070 3080 3090 3100 3110 3120
VFMSRTKSGS KSSICESSSL ISSATAAALL SSGAVDYCLH VLKSLLEYWK SQQNDEEPVA
3130 3140 3150 3160 3170 3180
TSQLLKPHTT SSPPDMSPFF LRQYVKGHAA DVFEAYTQLL TEMVLRLPYQ IKKITDTNSR
3190 3200 3210 3220 3230 3240
IPPPVFDHSW FYFLSEYLMI QQTPFVRRQV RKLLLFICGS KEKYRQLRDL HTLDSHVRGI
3250 3260 3270 3280 3290 3300
KKLLEEQGIF LRASVVTASS GSALQYDTLI SLMEHLKACA EIAAQRTINW QKFCIKDDSV
3310 3320 3330 3340 3350 3360
LYFLLQVSFL VDEGVSPVLL QLLSCALCGS KVLAALAASS GSSSASSSSA PVAASSGQAT
3370 3380 3390 3400 3410 3420
TQSKSSTKKS KKEEKEKEKD GETSGSQEDQ LCTALVNQLN KFADKETLIQ FLRCFLLESN
3430 3440 3450 3460 3470 3480
SSSVRWQAHC LTLHIYRNSS KSQQELLLDL MWSIWPELPA YGRKAAQFVD LLGYFSLKTP
3490 3500 3510 3520 3530 3540
QTEKKLKEYS QKAVEILRTQ NHILTNHPNS NIYNTLSGLV EFDGYYLESD PCLVCNNPEV
3550 3560 3570 3580 3590 3600
PFCYIKLSSI KVDTRYTTTQ QVVKLIGSHT ISKVTVKIGD LKRTKMVRTI NLYYNNRTVQ
3610 3620 3630 3640 3650 3660
AIVELKNKPA RWHKAKKVQL TPGQTEVKID LPLPIVASNL MIEFADFYEN YQASTETLQC
3670 3680 3690 3700 3710 3720
PRCSASVPAN PGVCGNCGEN VYQCHKCRSI NYDEKDPFLC NACGFCKYAR FDFMLYAKPC
3730 3740 3750 3760 3770 3780
CAVDPIENEE DRKKAVSNIN TLLDKADRVY HQLMGHRPQL ENLLCKVNEA APEKPQDDSG
3790 3800 3810 3820 3830 3840
TAGGISSTSA SVNRYILQLA QEYCGDCKNS FDELSKIIQK VFASRKELLE YDLQQREAAT
3850 3860 3870 3880 3890 3900
KSSRTSVQPT FTASQYRALS VLGCGHTSST KCYGCASAVT EHCITLLRAL ATNPALRHIL
3910 3920 3930 3940 3950 3960
VSQGLIRELF DYNLRRGAAA MREEVRQLMC LLTRDNPEAT QQMNDLIIGK VSTALKGHWA
3970 3980 3990 4000 4010 4020
NPDLASSLQY EMLLLTDSIS KEDSCWELRL RCALSLFLMA VNIKTPVVVE NITLMCLRIL
4030 4040 4050 4060 4070 4080
QKLIKPPAPT SKKNKDVPVE ALTTVKPYCN EIHAQAQLWL KRDPKASYDA WKKCLPIRGI
4090 4100 4110 4120 4130 4140
DGNGKAPSKS ELRHLYLTEK YVWRWKQFLS RRGKRTSPLD LKLGHNNWLR QVLFTPATQA
4150 4160 4170 4180 4190 4200
ARQAACTIVE ALATIPSRKQ QVLDLLTSYL DELSIAGECA AEYLALYQKL ITSAHWKVYL
4210 4220 4230 4240 4250 4260
AARGVLPYVG NLITKEIARL LALEEATLST DLQQGYALKS LTGLLSSFVE VESIKRHFKS
4270 4280 4290 4300 4310 4320
RLVGTVLNGY LCLRKLVVQR TKLIDETQDM LLEMLEDMTT GTESETKAFM AVCIETAKRY
4330 4340 4350 4360 4370 4380
NLDDYRTPVF IFERLCSIIY PEENEVTEFF VTLEKDPQQE DFLQGRMPGN PYSSNEPGIG
4390 4400 4410 4420 4430 4440
PLMRDIKNKI CQDCDLVALL EDDSGMELLV NNKIISLDLP VAEVYKKVWC TTNEGEPMRI
4450 4460 4470 4480 4490 4500
VYRMRGLLGD ATEEFIESLD STTDEEEDEE EVYKMAGVMA QCGGLECMLN RLAGIRDFKQ
4510 4520 4530 4540 4550 4560
GRHLLTVLLK LFSYCVKVKV NRQQLVKLEM NTLNVMLGTL NLALVAEQES KDSGGAAVAE
4570 4580 4590 4600 4610 4620
QVLSIMEIIL DESNAEPLSE DKGNLLLTGD KDQLVMLLDQ INSTFVRSNP SVLQGLLRII
4630 4640 4650 4660 4670 4680
PYLSFGEVEK MQILVERFKP YCNFDKYDED HSGDDKVFLD CFCKIAAGIK NNSNGHQLKD
4690 4700 4710 4720 4730 4740
LILQKGITQN ALDYMKKHIP SAKNLDADIW KKFLSRPALP FILRLLRGLA IQHPGTQVLI
4750 4760 4770 4780 4790 4800
GTDSIPNLHK LEQVSSDEGI GTLAENLLEA LREHPDVNKK IDAARRETRA EKKRMAMAMR
4810 4820 4830 4840 4850 4860
QKALGTLGMT TNEKGQVVTK TALLKQMEEL IEEPGLTCCI CREGYKFQPT KVLGIYTFTK
4870 4880 4890 4900 4910 4920
RVALEEMENK PRKQQGYSTV SHFNIVHYDC HLAAVRLARG REEWESAALQ NANTKCNGLL
4930 4940 4950 4960 4970 4980
PVWGPHVPES AFATCLARHN TYLQECTGQR EPTYQLNIHD IKLLFLRFAM EQSFSADTGG
4990 5000 5010 5020 5030 5040
GGRESNIHLI PYIIHTVLYV LNTTRATSRE EKNLQGFLEQ PKEKWVESAF EVDGPYYFTV
5050 5060 5070 5080 5090 5100
LALHILPPEQ WRATRVEILR RLLVTSQARA VAPGGATRLT DKAVKDYSAY RSSLLFWALV
5110 5120 5130 5140 5150 5160
DLIYNMFKKV PTSNTEGGWS CSLAEYIRHN DMPIYEAADK ALKTFQEEFM PVETFSEFLD
5170 5180
VAGLLSEITD PESFLKDLLN SVP
Protein Neighborhood
Domains & Features
14 N-termini - 7 C-termini - 6 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q5T4S7-1-unknown | MATSGG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q5T4S7-1-unknown | MATSGG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93761 | |||
| Q5T4S7-1-unknown | MATSGG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93762 | |||
| Q5T4S7-1-unknown | MATSGG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93763 | |||
| Q5T4S7-1-unknown | MATSGG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93764 | |||
| Q5T4S7-2-acetylation | ATSGGE... | 2 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | ||
| Q5T4S7-2-acetylation | ATSGGE... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt178729 | ||
| Q5T4S7-2-acetylation | ATSGGE... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt178730 | ||
| Q5T4S7-2-acetylation | ATSGGE... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt178731 | ||
| Q5T4S7-2-acetylation | ATSGGE... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt178732 | ||
| Q5T4S7-215-unknown | TLVEGE... | 215 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12505 | |||
| Q5T4S7-215-unknown | TLVEGE... | 215 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt147183 | |||
| Q5T4S7-215-unknown | TLVEGE... | 215 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt147185 | |||
| Q5T4S7-215-unknown | TLVEGE... | 215 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt147186 | |||
| Q5T4S7-215-unknown | TLVEGE... | 215 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt147187 | |||
| Q5T4S7-581-unknown | SSQDDD... | 581 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176796 | |||
| Q5T4S7-581-unknown | SSQDDD... | 581 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176797 | |||
| Q5T4S7-581-unknown | SSQDDD... | 581 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176798 | |||
| Q5T4S7-581-unknown | SSQDDD... | 581 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176799 | |||
| Q5T4S7-581- | SSQDDD... | 581 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
| Q5T4S7-1180-unknown | NFNEEG... | 1180 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6522 | |||
| Q5T4S7-1180-unknown | NFNEEG... | 1180 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157609 | |||
| Q5T4S7-1180-unknown | NFNEEG... | 1180 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157610 | |||
| Q5T4S7-1180-unknown | NFNEEG... | 1180 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157611 | |||
| Q5T4S7-1180-unknown | NFNEEG... | 1180 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157612 | |||
| Q5T4S7-2464- | SAAPTT... | 2464 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
| Q5T4S7-2464-unknown | SAAPTT... | 2464 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt178059 | |||
| Q5T4S7-2464-unknown | SAAPTT... | 2464 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt178060 | |||
| Q5T4S7-2897-unknown | SGGSAV... | 2897 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12510 | |||
| Q5T4S7-2897-unknown | SGGSAV... | 2897 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159265 | |||
| Q5T4S7-2897-unknown | SGGSAV... | 2897 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159268 | |||
| Q5T4S7-2897-unknown | SGGSAV... | 2897 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159271 | |||
| Q5T4S7-2904-unknown | SVAGEH... | 2904 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7901 | |||
| Q5T4S7-2904-unknown | SVAGEH... | 2904 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
| Q5T4S7-2904-unknown | SVAGEH... | 2904 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159266 | |||
| Q5T4S7-2904-unknown | SVAGEH... | 2904 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159269 | |||
| Q5T4S7-2904-unknown | SVAGEH... | 2904 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159273 | |||
| Q5T4S7-2904- | SVAGEH... | 2904 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
| Q5T4S7-2904- | SVAGEH... | 2904 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
| Q5T4S7-2904- | SVAGEH... | 2904 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
| Q5T4S7-2904- | SVAGEH... | 2904 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
| Q5T4S7-2904- | SVAGEH... | 2904 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
| Q5T4S7-2904- | SVAGEH... | 2904 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
| Q5T4S7-2904- | SVAGEH... | 2904 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
| Q5T4S7-2904- | SVAGEH... | 2904 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
| Q5T4S7-3586-unknown | MVRTIN... | 3586 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93765 | |||
| Q5T4S7-3586-unknown | MVRTIN... | 3586 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt99765 | |||
| Q5T4S7-3586-unknown | MVRTIN... | 3586 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt99764 | |||
| Q5T4S7-3586-unknown | MVRTIN... | 3586 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt99766 | |||
| Q5T4S7-4394-unknown | CDLVAL... | 4394 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12514 | |||
| Q5T4S7-4394-unknown | CDLVAL... | 4394 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159350 | |||
| Q5T4S7-4394-unknown | CDLVAL... | 4394 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159351 | |||
| Q5T4S7-4394-unknown | CDLVAL... | 4394 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159353 | |||
| Q5T4S7-4758-unknown | EGIGTL... | 4758 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12518 | |||
| Q5T4S7-4758-unknown | EGIGTL... | 4758 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159355 | |||
| Q5T4S7-4758-unknown | EGIGTL... | 4758 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159356 | |||
| Q5T4S7-4758-unknown | EGIGTL... | 4758 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159358 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...PISTQT | 214 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12505 | |||
| ...PISTQT | 214 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt130523 | |||
| ...PISTQT | 214 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt130525 | |||
| ...PISTQT | 214 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt130526 | |||
| ...PISTQT | 214 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt130527 | |||
| ...AYLLQN | 1179 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6522 | |||
| ...AYLLQN | 1179 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141108 | |||
| ...AYLLQN | 1179 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141109 | |||
| ...AYLLQN | 1179 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141110 | |||
| ...AYLLQN | 1179 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141111 | |||
| ...SVGSES | 2896 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12510 | |||
| ...SVGSES | 2896 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142769 | |||
| ...SVGSES | 2896 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142772 | |||
| ...SVGSES | 2896 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142775 | |||
| ...GSAVDS | 2903 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7901 | |||
| ...GSAVDS | 2903 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142770 | |||
| ...GSAVDS | 2903 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142773 | |||
| ...GSAVDS | 2903 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142777 | |||
| ...KICQDC | 4393 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12514 | |||
| ...KICQDC | 4393 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142855 | |||
| ...KICQDC | 4393 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142856 | |||
| ...KICQDC | 4393 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142858 | |||
| ...QVSSDE | 4757 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12518 | |||
| ...QVSSDE | 4757 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142869 | |||
| ...QVSSDE | 4757 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142870 | |||
| ...QVSSDE | 4757 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142872 | |||
| ...LNSVP | 5183 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...LNSVP | 5183 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt89380 | |||
| ...LNSVP | 5183 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt89381 | |||
| ...LNSVP | 5183 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt89379 |
Cleavages
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|