Q15365: Poly(rC)-binding protein 1
Protein names | - Poly(rC)-binding protein 1 - Alpha-CP1 - Heterogeneous nuclear ribonucleoprotein E1 - hnRNP E1 - Nucleic acid-binding protein SUB2.3 |
---|---|
Gene names | PCBP1 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q15365 |
31
N-termini
14
C-termini
13
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MDAGVTESGL NVTLTIRLLM HGKEVGSIIG KKGESVKRIR EESGARINIS EGNCPERIIT
70 80 90 100 110 120
LTGPTNAIFK AFAMIIDKLE EDINSSMTNS TAASRPPVTL RLVVPATQCG SLIGKGGCKI
130 140 150 160 170 180
KEIRESTGAQ VQVAGDMLPN STERAITIAG VPQSVTECVK QICLVMLETL SQSPQGRVMT
190 200 210 220 230 240
IPYQPMPASS PVICAGGQDR CSDAAGYPHA THDLEGPPLD AYSIQGQHTI SPLDLAKLNQ
250 260 270 280 290 300
VARQQSHFAM MHGGTGFAGI DSSSPEVKGY WASLDASTQT THELTIPNNL IGCIIGRQGA
310 320 330 340 350
NINEIRQMSG AQIKIANPVE GSSGRQVTIT GSAASISLAQ YLINARLSSE KGMGCS
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
31 N-termini - 14 C-termini - 13 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q15365-1-Acetylation | MDAGVT... | 1 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q15365-1-Acetylation | MDAGVT... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
Q15365-1-Acetylation | MDAGVT... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | ||
Q15365-61-unknown | LTGPTN... | 61 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4071 | |||
Q15365-63-unknown | GPTNAI... | 63 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6451 | |||
Q15365-74- | MIIDKL... | 74 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q15365-74- | MIIDKL... | 74 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q15365-85- | SSMTNS... | 85 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q15365-85- | SSMTNS... | 85 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q15365-85- | SSMTNS... | 85 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
Q15365-85- | SSMTNS... | 85 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q15365-85- | SSMTNS... | 85 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q15365-90- | STAASR... | 90 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q15365-90- | STAASR... | 90 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q15365-90- | STAASR... | 90 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q15365-90- | STAASR... | 90 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
Q15365-90- | STAASR... | 90 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q15365-90- | STAASR... | 90 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q15365-133- | VAGDML... | 133 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q15365-137-unknown | MLPNST... | 137 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12360 | |||
Q15365-148-unknown | IAGVPQ... | 148 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6452 | |||
Q15365-148-unknown | IAGVPQ... | 148 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4072 | |||
Q15365-189-unknown | SSPVIC... | 189 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14532 | |||
Q15365-204- | AAGYPH... | 204 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q15365-204- | AAGYPH... | 204 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q15365-221- | AYSIQG... | 221 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q15365-221- | AYSIQG... | 221 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q15365-221- | AYSIQG... | 221 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q15365-223-unknown | SIQGQH... | 223 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q15365-223- | SIQGQH... | 223 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q15365-223- | SIQGQH... | 223 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
Q15365-223- | SIQGQH... | 223 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q15365-223- | SIQGQH... | 223 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
Q15365-223- | SIQGQH... | 223 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q15365-223- | SIQGQH... | 223 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q15365-226- | GQHTIS... | 226 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q15365-226-unknown | GQHTIS... | 226 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6453 | |||
Q15365-229- | TISPLD... | 229 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q15365-229- | TISPLD... | 229 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
Q15365-229- | TISPLD... | 229 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q15365-229- | TISPLD... | 229 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
Q15365-229- | TISPLD... | 229 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q15365-234-unknown | DLAKLN... | 234 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14533 | |||
Q15365-246- | SHFAMM... | 246 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
Q15365-248- | FAMMHG... | 248 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q15365-248- | FAMMHG... | 248 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q15365-248- | FAMMHG... | 248 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
Q15365-249-unknown | AMMHGG... | 249 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q15365-249- | AMMHGG... | 249 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q15365-249- | AMMHGG... | 249 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
Q15365-249- | AMMHGG... | 249 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
Q15365-249- | AMMHGG... | 249 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q15365-249- | AMMHGG... | 249 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q15365-250- | MMHGGT... | 250 | Subtiligase Based Positive Selection | Wells | THP_untreated | 23264352 | |||
Q15365-251- | MHGGTG... | 251 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q15365-251- | MHGGTG... | 251 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
Q15365-251- | MHGGTG... | 251 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
Q15365-251- | MHGGTG... | 251 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q15365-251- | MHGGTG... | 251 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
Q15365-251- | MHGGTG... | 251 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q15365-251- | MHGGTG... | 251 | Subtiligase Based Positive Selection | Wells | THP_untreated | 23264352 | |||
Q15365-251- | MHGGTG... | 251 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q15365-251-unknown | MHGGTG... | 251 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q15365-251-unknown | MHGGTG... | 251 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q15365-252-unknown | HGGTGF... | 252 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6454 | |||
Q15365-253- | GGTGFA... | 253 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q15365-253- | GGTGFA... | 253 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q15365-253- | GGTGFA... | 253 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
Q15365-253- | GGTGFA... | 253 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q15365-253-unknown | GGTGFA... | 253 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7856 | |||
Q15365-254-unknown | GTGFAG... | 254 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4073 | |||
Q15365-257-unknown | FAGIDS... | 257 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4074 | |||
Q15365-259-unknown | GIDSSS... | 259 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6455 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...ERIITL | 60 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4071 | |||
...IITLTG | 62 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6451 | |||
...QVAGDM | 136 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12360 | |||
...ERAITI | 147 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6452 | |||
...ERAITI | 147 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4072 | |||
...QPMPAS | 188 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14532 | |||
...AYSIQG | 225 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6453 | |||
...TISPLD | 233 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14533 | |||
...HFAMMH | 251 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6454 | |||
...FAMMHG | 252 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7856 | |||
...AMMHGG | 253 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4073 | |||
...HGGTGF | 256 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4074 | |||
...GTGFAG | 258 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6455 | |||
...GMGCS | 356 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...GMGCS | 356 | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345, | |||
...GMGCS | 356 | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345, | |||
...GMGCS | 356 | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345, | |||
...GMGCS | 356 | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345, |
Cleavages
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|