Q07021: Complement component 1 Q subcomponent-binding protein, mitochondrial

General Information

Protein names	- Complement component 1 Q subcomponent-binding protein, mitochondrial - ASF/SF2-associated protein p32 - Glycoprotein gC1qBP - C1qBP - Hyaluronan-binding protein 1 - Mitochondrial matrix protein p32 - gC1q-R protein - p33 - SF2AP32 {ECO:0000303\|PubMed:18191643}
Gene names	C1QBP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q07021

18 N-termini

5 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLPLLRCVPR VLGSSVAGLR AAAPASPFRQ LLQPAPRLCT RPFGLLSVRA GSERRPGLLR
        70         80         90        100        110        120
PRGPCACGCG CGSLHTDGDK AFVDFLSDEI KEERKIQKHK TLPKMSGGWE LELNGTEAKL
       130        140        150        160        170        180
VRKVAGEKIT VTFNINNSIP PTFDGEEEPS QGQKVEEQEP ELTSTPNFVV EVIKNDDGKK
       190        200        210        220        230        240
ALVLDCHYPE DEVGQEDEAE SDIFSIREVS FQSTGESEWK DTNYTLNTDS LDWALYDHLM
       250        260        270        280
DFLADRGVDN TFADELVELS TALEHQEYIT FLEDLKSFVK SQ

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

18 N-termini - 5 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q07021-66-	ACGCGC...	66		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07021-66-	ACGCGC...	66		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q07021-72-	GSLHTD...	72		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07021-73-	SLHTDG...	73		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07021-74-unknown	LHTDGD...	74	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q07021-74-unknown	LHTDGD...	74		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q07021-74-unknown	LHTDGD...	74		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q07021-74-	LHTDGD...	74		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q07021-74-	LHTDGD...	74		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q07021-74-	LHTDGD...	74		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q07021-74-	LHTDGD...	74		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07021-74-	LHTDGD...	74		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q07021-74-	LHTDGD...	74		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q07021-74-	LHTDGD...	74		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q07021-74-	LHTDGD...	74		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q07021-75-	HTDGDK...	75		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07021-76-	TDGDKA...	76		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q07021-76-	TDGDKA...	76		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07021-78-	GDKAFV...	78		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07021-83-	VDFLSD...	83		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07021-85-	FLSDEI...	85		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07021-105-unknown	MSGGWE...	105	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000460308
Q07021-105-unknown	MSGGWE...	105	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000460638
Q07021-138-unknown	SIPPTF...	138	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7735
Q07021-138-	SIPPTF...	138		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q07021-138-	SIPPTF...	138		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07021-153-unknown	QKVEEQ...	153	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21617
Q07021-164-	STPNFV...	164		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q07021-165-unknown	TPNFVV...	165	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19362
Q07021-168-	FVVEVI...	168		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q07021-168-	FVVEVI...	168		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07021-168-	FVVEVI...	168		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q07021-168-	FVVEVI...	168		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q07021-187-	HYPEDE...	187		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q07021-187-	HYPEDE...	187		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FNINNS	137	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7735
...EPSQGQ	152	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21617
...PELTST	164	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19362
...SFVKSQ	281	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000460638
...FVKSQ	282	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	137	INNS.\|.SIPP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MMP14_HUMAN	152	SQGQ.\|.QKVE	inferred from experiment	unknown	MEROPS	Strongin AY	Rozanov DV et al.:The hemopexin-like C-terminal d... (M10.014)	11773076,
MEP1B_HUMAN	164	LTST.\|.TPNF	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)