Q05639: Elongation factor 1-alpha 2

General Information

Protein names	- Elongation factor 1-alpha 2 - EF-1-alpha-2 - Eukaryotic elongation factor 1 A-2 - eEF1A-2 - Statin-S1
Gene names	EEF1A2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q05639

9 N-termini

9 C-termini

9 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGKEKTHINI VVIGHVDSGK STTTGHLIYK CGGIDKRTIE KFEKEAAEMG KGSFKYAWVL
        70         80         90        100        110        120
DKLKAERERG ITIDISLWKF ETTKYYITII DAPGHRDFIK NMITGTSQAD CAVLIVAAGV
       130        140        150        160        170        180
GEFEAGISKN GQTREHALLA YTLGVKQLIV GVNKMDSTEP AYSEKRYDEI VKEVSAYIKK
       190        200        210        220        230        240
IGYNPATVPF VPISGWHGDN MLEPSPNMPW FKGWKVERKE GNASGVSLLE ALDTILPPTR
       250        260        270        280        290        300
PTDKPLRLPL QDVYKIGGIG TVPVGRVETG ILRPGMVVTF APVNITTEVK SVEMHHEALS
       310        320        330        340        350        360
EALPGDNVGF NVKNVSVKDI RRGNVCGDSK SDPPQEAAQF TSQVIILNHP GQISAGYSPV
       370        380        390        400        410        420
IDCHTAHIAC KFAELKEKID RRSGKKLEDN PKSLKSGDAA IVEMVPGKPM CVESFSQYPP
       430        440        450        460
LGRFAVRDMR QTVAVGVIKN VEKKSGGAGK VTKSAQKAQK AGK

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

9 N-termini - 9 C-termini - 9 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q05639-1-unknown	MGKEKT...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q05639-13-unknown	IGHVDS...	13	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7732
Q05639-253-unknown	VYKIGG...	253	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11924
Q05639-254-unknown	YKIGGI...	254	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15392
Q05639-281-unknown	APVNIT...	281	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19351
Q05639-301-unknown	EALPGD...	301	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6238
Q05639-302-unknown	ALPGDN...	302	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19352
Q05639-302-unknown	ALPGDN...	302	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q05639-302-unknown	ALPGDN...	302	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q05639-362-unknown	DCHTAH...	362	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7733
Q05639-362-unknown	DCHTAH...	362	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6239
Q05639-371-unknown	KFAELK...	371	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14376

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...INIVVI	12	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7732
...LPLQDV	252	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11924
...PLQDVY	253	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15392
...MVVTFA	280	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19351
...HEALSE	300	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6238
...EALSEA	301	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19352
...YSPVID	361	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7733
...YSPVID	361	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6239
...AHIACK	370	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14376
...QKAGK	463	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	12	IVVI.\|.IGHV	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	252	LQDV.\|.VYKI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
HTRA2_HUMAN	253	QDVY.\|.YKIG	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
MEP1B_HUMAN	280	VTFA.\|.APVN	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	300	ALSE.\|.EALP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1B_HUMAN	301	LSEA.\|.ALPG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATS_HUMAN	361	PVID.\|.DCHT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	361	PVID.\|.DCHT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAM_HUMAN	370	IACK.\|.KFAE	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)