P62906: 60S ribosomal protein L10a

General Information

Protein names	- 60S ribosomal protein L10a - CSA-19 - Large ribosomal subunit protein uL1 {ECO:0000303\|PubMed:24524803} - Neural precursor cell expressed developmentally down-regulated protein 6 - NEDD-6
Gene names	RPL10A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P62906

8 N-termini

7 C-termini

8 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSSKVSRDTL YEAVREVLHG NQRKRRKFLE TVELQISLKN YDPQKDKRFS GTVRLKSTPR
        70         80         90        100        110        120
PKFSVCVLGD QQHCDEAKAV DIPHMDIEAL KKLNKNKKLV KKLAKKYDAF LASESLIKQI
       130        140        150        160        170        180
PRILGPGLNK AGKFPSLLTH NENMVAKVDE VKSTIKFQMK KVLCLAVAVG HVKMTDDELV
       190        200        210
YNIHLAVNFL VSLLKKNWQN VRALYIKSTM GKPQRLY

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

8 N-termini - 7 C-termini - 8 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P62906-2-unknown	MSSKVS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62906-2-Acetylation	SSKVSR...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62906-2-Acetylation	SSKVSR...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P62906-2-Acetylation	SSKVSR...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P62906-9-unknown	TLYEAV...	9		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11784
P62906-67-unknown	VLGDQQ...	67		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3896
P62906-67-unknown	VLGDQQ...	67		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6137
P62906-115-unknown	SLIKQI...	115		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11785
P62906-138-unknown	LTHNEN...	138		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3897
P62906-139-unknown	THNENM...	139		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7657
P62906-139-unknown	THNENM...	139		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6138
P62906-140-unknown	HNENMV...	140		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6139

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KVSRDT	8	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11784
...KFSVCV	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3896
...KFSVCV	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6137
...FLASES	114	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11785
...KFPSLL	137	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3897
...FPSLLT	138	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7657
...FPSLLT	138	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6138
...PSLLTH	139	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6139
...PQRLY	217	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	8	SRDT.\|.TLYE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
CATB_HUMAN	66	SVCV.\|.VLGD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	66	SVCV.\|.VLGD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	114	ASES.\|.SLIK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
CATB_HUMAN	137	PSLL.\|.LTHN	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	138	SLLT.\|.THNE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	138	SLLT.\|.THNE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	139	LLTH.\|.HNEN	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)