Q5VTL8: Pre-mRNA-splicing factor 38B

General Information

Protein names	- Pre-mRNA-splicing factor 38B - Sarcoma antigen NY-SAR-27
Gene names	PRPF38B
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q5VTL8

6 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MANNSPALTG NSQPQHQAAA AAAQQQQQCG GGGATKPAVS GKQGNVLPLW GNEKTMNLNP
        70         80         90        100        110        120
MILTNILSSP YFKVQLYELK TYHEVVDEIY FKVTHVEPWE KGSRKTAGQT GMCGGVRGVG
       130        140        150        160        170        180
TGGIVSTAFC LLYKLFTLKL TRKQVMGLIT HTDSPYIRAL GFMYIRYTQP PTDLWDWFES
       190        200        210        220        230        240
FLDDEEDLDV KAGGGCVMTI GEMLRSFLTK LEWFSTLFPR IPVPVQKNID QQIKTRPRKI
       250        260        270        280        290        300
KKDGKEGAEE IDRHVERRRS RSPRRSLSPR RSPRRSRSRS HHREGHGSSS FDRELEREKE
       310        320        330        340        350        360
RQRLEREAKE REKERRRSRS IDRGLERRRS RSRERHRSRS RSRDRKGDRR DRDREREKEN
       370        380        390        400        410        420
ERGRRRDRDY DKERGNEREK ERERSRERSK EQRSRGEVEE KKHKEDKDDR RHRDDKRDSK
       430        440        450        460        470        480
KEKKHSRSRS RERKHRSRSR SRNAGKRSRS RSKEKSSKHK NESKEKSNKR SRSGSQGRTD
       490        500        510        520        530        540
SVEKSKKREH SPSKEKSRKR SRSKERSHKR DHSDSKDQSD KHDRRRSQSI EQESQEKQHK

NKDETV

Isoforms

- Isoform 2 of Pre-mRNA-splicing factor 38B

Sequence View

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Evidence Codes:

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Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q5VTL8-2-unknown	MANNSP...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q5VTL8-1-unknown	MANNSP...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86067
Q5VTL8-2-Acetylation	ANNSPA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q5VTL8-2-Acetylation	ANNSPA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111038
Q5VTL8-26-unknown	QQQCGG...	26		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7905
Q5VTL8-26-unknown	QQQCGG...	26		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt137302
Q5VTL8-27-unknown	QQCGGG...	27		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7907
Q5VTL8-27-unknown	QQCGGG...	27		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt137366
Q5VTL8-28-unknown	QCGGGG...	28		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7909
Q5VTL8-28-unknown	QCGGGG...	28		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt137431

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AAAQQQ	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7905
...AAAQQQ	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120236
...AAQQQQ	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7907
...AAQQQQ	26	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120311
...AQQQQQ	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7909
...AQQQQQ	27	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120389
...KDETV	546	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	25	AQQQ.\|.QQQC	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	26	QQQQ.\|.QQCG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	27	QQQQ.\|.QCGG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)