Q5VW32: BRO1 domain-containing protein BROX

General Information

Protein names	- BRO1 domain-containing protein BROX - BRO1 domain- and CAAX motif-containing protein
Gene names	BROX
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q5VW32

2 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTHWFHRNPL KATAPVSFNY YGVVTGPSAS KICNDLRSSR ARLLELFTDL SCNPEMMKNA
        70         80         90        100        110        120
ADSYFSLLQG FINSLDESTQ ESKLRYIQNF KWTDTLQGQV PSAQQDAVFE LISMGFNVAL
       130        140        150        160        170        180
WYTKYASRLA GKENITEDEA KEVHRSLKIA AGIFKHLKES HLPKLITPAE KGRDLESRLI
       190        200        210        220        230        240
EAYVIQCQAE AQEVTIARAI ELKHAPGLIA ALAYETANFY QKADHTLSSL EPAYSAKWRK
       250        260        270        280        290        300
YLHLKMCFYT AYAYCYHGET LLASDKCGEA IRSLQEAEKL YAKAEALCKE YGETKGPGPT
       310        320        330        340        350        360
VKPSGHLFFR KLGNLVKNTL EKCQRENGFI YFQKIPTEAP QLELKANYGL VEPIPFEFPP
       370        380        390        400        410
TSVQWTPETL AAFDLTKRPK DDSTKPKPEE EVKPVKEPDI KPQKDTGCYI S

Isoforms

- Isoform 2 of BRO1 domain-containing protein BROX

Sequence View

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q5VW32-1-unknown	MTHWFH...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q5VW32-70-unknown	GFINSL...	70	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6536
Q5VW32-70-unknown	GFINSL...	70	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7911

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FSLLQG	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6536
...FSLLQG	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7911
...ALAYET	215	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000398862
...KDTGCY	408	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	69	LLQG.\|.GFIN	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	69	LLQG.\|.GFIN	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)