Q6P597: Kinesin light chain 3

General Information

Protein names	- Kinesin light chain 3 - KLC2-like - kinesin light chain 2
Gene names	KLC3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6P597

3 N-termini

2 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Kinesin light chain 3 - Isoform 3 of Kinesin light chain 3

Sequence View

        10         20         30         40         50         60
MSVQVAAPGS AGLGPERLSP EELVRQTRQV VQGLEALRAE HHGLAGHLAE ALAGQGPAAG
        70         80         90        100        110        120
LEMLEEKQQV VSHSLEAIEL GLGEAQVLLA LSAHVGALEA EKQRLRSQAR RLAQENVWLR
       130        140        150        160        170        180
EELEETQRRL RASEESVAQL EEEKRHLEFL GQLRQYDPPA ESQQSESPPR RDSLASLFPS
       190        200        210        220        230        240
EEEERKGPEA AGAAAAQQGG YEIPARLRTL HNLVIQYAGQ GRYEVAVPLC RQALEDLERS
       250        260        270        280        290        300
SGHCHPDVAT MLNILALVYR DQNKYKEATD LLHDALQIRE QTLGPEHPAV AATLNNLAVL
       310        320        330        340        350        360
YGKRGRYREA EPLCQRALEI REKVLGADHP DVAKQLNNLA LLCQNQGKFE DVERHYARAL
       370        380        390        400        410        420
SIYEALGGPH DPNVAKTKNN LASAYLKQNK YQQAEELYKE ILHKEDLPAP LGAPNTGTAG
       430        440        450        460        470        480
DAEQALRRSS SLSKIRESIR RGSEKLVSRL RGEAAAGAAG MKRAMSLNTL NVDAPRAPGT
       490        500
QFPSWHLDKA PRTLSASTQD LSPH         10         20         30         40         50         60
MSVQVAAPGS AGLGPERLSP EELVRQTRQV VQGLEALRAE HHGLAGHLAE ALAGQGPAAG
        70         80         90        100        110        120
LEMLEEKQQV VSHSLEAIEL GLGEAQVLLA LSAHVGALEA EKQRLRSQAR RLAQENVWLR
       130        140        150        160        170        180
EELEETQRRL RASEESVAQL EEEKRHLEFL GQLRQYDPPA ESQQSESPPR RDSLASLFPS
       190        200        210        220        230        240
EEEERKGPEA AGAAAAQQGG YEIPARLRTL HNLVIQYAGQ GRYEVAVPLC RQALEDLERS
       250        260        270        280        290        300
SGHCHPDVAT MLNILALVYR DQNKYKEATD LLHDALQIRE QTLGPEHPAV AATLNNLAVL
       310        320        330        340        350        360
YGKRGRYREA EPLCQRALEI REKVLGADHP DVAKQLNNLA LLCQNQGKFE DVERHYARAL
       370        380        390        400        410        420
SIYEALGGPH DPNVAKTKNN LASAYLKQNK YQQAEELYKE ILHKEDLPAP LGAPNTGTAG
       430        440        450        460        470        480
DAEQALRRSS SLSKIRESIR RGSEKLVSRL RGEAAAGAAG MKRAMSLNTL NVDAPRAPGT
       490        500
QFPSWHLDKA PRTLSASTQD LSPH

Filter Information:

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6P597-1-unknown	MSVQVA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6P597-1-unknown	MSVQVA...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt79054
Q6P597-1-unknown	MSVQVA...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt107084
Q6P597-2-acetylation	SVQVAA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q6P597-2-acetylation	SVQVAA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178838
Q6P597-2-acetylation	SVQVAA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178837
Q6P597-368-unknown	GPHDPN...	368		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6554
Q6P597-368-unknown	GPHDPN...	368		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7919
Q6P597-368-unknown	GPHDPN...	368		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151352
Q6P597-368-unknown	GPHDPN...	368		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151675

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YEALGG	367	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6554
...YEALGG	367	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7919
...YEALGG	367	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134754
...YEALGG	367	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135078
...DLSPH	504	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DLSPH	504	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74672
...DLSPH	504	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74673

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	367	ALGG.\|.GPHD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	367	ALGG.\|.GPHD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)