P47914: 60S ribosomal protein L29

General Information

Protein names	- 60S ribosomal protein L29 - Cell surface heparin-binding protein HIP - Large ribosomal subunit protein eL29 {ECO:0000303\|PubMed:24524803}
Gene names	RPL29
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P47914

24 N-termini

15 C-termini

15 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAKSKNHTTH NQSRKWHRNG IKKPRSQRYE SLKGVDPKFL RNMRFAKKHN KKGLKKMQAN
        70         80         90        100        110        120
NAKAMSARAE AIKALVKPKE VKPKIPKGVS RKLDRLAYIA HPKLGKRARA RIAKGLRLCR
       130        140        150
PKAKAKAKAK DQTKAQAAAP ASVPAQAPKR TQAPTKASE

Isoforms

Sequence View

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Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

24 N-termini - 15 C-termini - 15 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P47914-2-unknown	AKSKNH...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P47914-30-unknown	ESLKGV...	30	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14143
P47914-33-unknown	KGVDPK...	33	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11551
P47914-33-unknown	KGVDPK...	33	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14144
P47914-55-unknown	KKMQAN...	55	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14145
P47914-56-unknown	KMQANN...	56	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14146
P47914-59-unknown	ANNAKA...	59	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14147
P47914-60-unknown	NNAKAM...	60	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14148
P47914-61-unknown	NAKAMS...	61	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14149
P47914-69-	AEAIKA...	69		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P47914-73-unknown	KALVKP...	73	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14150
P47914-74-	ALVKPK...	74		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P47914-74-	ALVKPK...	74		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P47914-74-	ALVKPK...	74		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P47914-76-unknown	VKPKEV...	76	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14151
P47914-97-unknown	AYIAHP...	97	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14152
P47914-128-unknown	KAKDQT...	128	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14153
P47914-129-	AKDQTK...	129		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P47914-131-	DQTKAQ...	131		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P47914-131-	DQTKAQ...	131		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P47914-135-unknown	AQAAAP...	135		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P47914-135-unknown	AQAAAP...	135		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P47914-135-	AQAAAP...	135		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P47914-135-	AQAAAP...	135		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P47914-135-	AQAAAP...	135		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P47914-137-unknown	AAAPAS...	137	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5892
P47914-137-unknown	AAAPAS...	137		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P47914-137-unknown	AAAPAS...	137		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P47914-137-	AAAPAS...	137		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P47914-137-	AAAPAS...	137		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P47914-138-	AAPASV...	138		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P47914-139-unknown	APASVP...	139	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7481
P47914-139-unknown	APASVP...	139	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19128
P47914-151-unknown	TQAPTK...	151		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P47914-151-	TQAPTK...	151		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...RSQRYE	29	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14143
...RYESLK	32	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11551
...RYESLK	32	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14144
...NKKGLK	54	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14145
...KKGLKK	55	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14146
...LKKMQA	58	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14147
...KKMQAN	59	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14148
...KMQANN	60	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14149
...RAEAIK	72	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14150
...AIKALV	75	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14151
...KLDRLA	96	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14152
...AKAKAK	127	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14153
...QTKAQA	136	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5892
...KAQAAA	138	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7481
...KAQAAA	138	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19128
...TKASE	159	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...TKASE	159		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...TKASE	159		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...TKASE	159		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...TKASE	159		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	29	QRYE.\|.ESLK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	32	ESLK.\|.KGVD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAM_HUMAN	32	ESLK.\|.KGVD	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	54	KGLK.\|.KKMQ	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	55	GLKK.\|.KMQA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	58	KMQA.\|.ANNA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	59	MQAN.\|.NNAK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	60	QANN.\|.NAKA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	72	EAIK.\|.KALV	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	75	KALV.\|.VKPK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	96	DRLA.\|.AYIA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	127	AKAK.\|.KAKD	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CATL1_HUMAN	136	KAQA.\|.AAAP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	138	QAAA.\|.APAS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1B_HUMAN	138	QAAA.\|.APAS	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)