P05386: 60S acidic ribosomal protein P1

General Information

Protein names	- 60S acidic ribosomal protein P1 - Large ribosomal subunit protein P1 {ECO:0000303\|PubMed:24524803}
Gene names	RPLP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P05386

20 N-termini

8 C-termini

9 Cleavages

0 Substrates

Sequence

10 20 30 40 50 60
MASVSELACI YSALILHDDE VTVTEDKINA LIKAAGVNVE PFWPGLFAKA LANVNIGSLI
70 80 90 100 110
CNVGAGGPAP AAGAAPAGGP APSTAAAPAE EKKVEAKKEE SEESDDDMGF GLFD

Isoforms

- Isoform 2 of 60S acidic ribosomal protein P1

Sequence View

10 20 30 40 50 60
MASVSELACI YSALILHDDE VTVTEDKINA LIKAAGVNVE PFWPGLFAKA LANVNIGSLI
70 80 90 100 110
CNVGAGGPAP AAGAAPAGGP APSTAAAPAE EKKVEAKKEE SEESDDDMGF GLFD

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

20 N-termini - 8 C-termini - 9 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P05386-1-unknown	MASVSE...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87827
P05386-2-unknown	MASVSE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P05386-2-Acetylation	ASVSEL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P05386-2-Acetylation	ASVSEL...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P05386-2-Acetylation	ASVSEL...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111690
P05386-12-	SALILH...	12			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P05386-12-	SALILH...	12			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P05386-12-	SALILH...	12			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P05386-12-	SALILH...	12			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P05386-13-	ALILHD...	13			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P05386-19-unknown	DEVTVT...	19		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P05386-34-	AAGVNV...	34			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P05386-53-unknown	NVNIGS...	53		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7201
P05386-53-unknown	NVNIGS...	53		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt196184
P05386-62-unknown	NVGAGG...	62		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3477
P05386-62-unknown	NVGAGG...	62		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138121
P05386-65-unknown	AGGPAP...	65		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5393
P05386-65-unknown	AGGPAP...	65		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3479
P05386-65-unknown	AGGPAP...	65		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138307
P05386-66-	GGPAPA...	66			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P05386-66-unknown	GGPAPA...	66		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175138
P05386-67-unknown	GPAPAA...	67		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5395
P05386-67-unknown	GPAPAA...	67		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138488
P05386-73-unknown	GAAPAG...	73		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3481
P05386-73-unknown	GAAPAG...	73		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139020
P05386-74-unknown	AAPAGG...	74		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5397
P05386-74-unknown	AAPAGG...	74		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3483
P05386-74-unknown	AAPAGG...	74		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139044
P05386-78-unknown	GGPAPS...	78		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164577
P05386-78-	GGPAPS...	78			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P05386-78-	GGPAPS...	78			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P05386-78-	GGPAPS...	78			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P05386-79-unknown	GPAPST...	79		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5399
P05386-79-unknown	GPAPST...	79		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139444
P05386-83-	STAAAP...	83			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P05386-83-unknown	STAAAP...	83		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169039

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AKALAN	52	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7201
...GSLICN	61	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3477
...ICNVGA	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5393
...ICNVGA	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3479
...NVGAGG	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5395
...PAPAAG	72	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3481
...PAPAAG	72	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122089
...APAAGA	73	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5397
...APAAGA	73	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3483
...APAAGA	73	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122115
...AAPAGG	78	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5399
...AAPAGG	78	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122531
...FGLFD	114	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FGLFD	114	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83445

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	52	ALAN.\|.NVNI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	61	LICN.\|.NVGA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	64	NVGA.\|.AGGP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	64	NVGA.\|.AGGP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	66	GAGG.\|.GPAP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	72	PAAG.\|.GAAP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	73	AAGA.\|.AAPA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	73	AAGA.\|.AAPA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	78	PAGG.\|.GPAP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)