P45984: Mitogen-activated protein kinase 9

General Information

Protein names	- Mitogen-activated protein kinase 9 - MAP kinase 9 - MAPK 9 - 2.7.11.24 {ECO:0000269\|PubMed:11062067, ECO:0000269\|PubMed:15805466, ECO:0000269\|PubMed:17875713, ECO:0000269\|PubMed:21110917, ECO:0000269\|PubMed:7969172, ECO:0000269\|PubMed:8001819, ECO:0000269\|PubMed:8654373} - JNK-55 - Stress-activated protein kinase 1a - SAPK1a - Stress-activated protein kinase JNK2 - c-Jun N-terminal kinase 2
Gene names	MAPK9
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P45984

2 N-termini

2 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform Alpha-1 of Mitogen-activated protein kinase 9 - Isoform Beta-1 of Mitogen-activated protein kinase 9 - Isoform Beta-2 of Mitogen-activated protein kinase 9 - Isoform 5 of Mitogen-activated protein kinase 9

Sequence View

        10         20         30         40         50         60
MSDSKCDSQF YSVQVADSTF TVLKRYQQLK PIGSGAQGIV CAAFDTVLGI NVAVKKLSRP
        70         80         90        100        110        120
FQNQTHAKRA YRELVLLKCV NHKNIISLLN VFTPQKTLEE FQDVYLVMEL MDANLCQVIH
       130        140        150        160        170        180
MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTACTNF
       190        200        210        220        230        240
MMTPYVVTRY YRAPEVILGM GYKENVDIWS VGCIMGELVK GCVIFQGTDH IDQWNKVIEQ
       250        260        270        280        290        300
LGTPSAEFMK KLQPTVRNYV ENRPKYPGIK FEELFPDWIF PSESERDKIK TSQARDLLSK
       310        320        330        340        350        360
MLVIDPDKRI SVDEALRHPY ITVWYDPAEA EAPPPQIYDA QLEEREHAIE EWKELIYKEV
       370        380        390        400        410        420
MDWEERSKNG VVKDQPSDAA VSSNATPSQS SSINDISSMS TEQTLASDTD SSLDASTGPL

EGCR         10         20         30         40         50         60
MSDSKCDSQF YSVQVADSTF TVLKRYQQLK PIGSGAQGIV CAAFDTVLGI NVAVKKLSRP
        70         80         90        100        110        120
FQNQTHAKRA YRELVLLKCV NHKNIISLLN VFTPQKTLEE FQDVYLVMEL MDANLCQVIH
       130        140        150        160        170        180
MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTACTNF
       190        200        210        220        230        240
MMTPYVVTRY YRAPEVILGM GYKENVDIWS VGCIMGELVK GCVIFQGTDH IDQWNKVIEQ
       250        260        270        280        290        300
LGTPSAEFMK KLQPTVRNYV ENRPKYPGIK FEELFPDWIF PSESERDKIK TSQARDLLSK
       310        320        330        340        350        360
MLVIDPDKRI SVDEALRHPY ITVWYDPAEA EAPPPQIYDA QLEEREHAIE EWKELIYKEV
       370        380        390        400        410        420
MDWEERSKNG VVKDQPSDAA VSSNATPSQS SSINDISSMS TEQTLASDTD SSLDASTGPL

EGCR         10         20         30         40         50         60
MSDSKCDSQF YSVQVADSTF TVLKRYQQLK PIGSGAQGIV CAAFDTVLGI NVAVKKLSRP
        70         80         90        100        110        120
FQNQTHAKRA YRELVLLKCV NHKNIISLLN VFTPQKTLEE FQDVYLVMEL MDANLCQVIH
       130        140        150        160        170        180
MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTACTNF
       190        200        210        220        230        240
MMTPYVVTRY YRAPEVILGM GYKENVDIWS VGCIMGELVK GCVIFQGTDH IDQWNKVIEQ
       250        260        270        280        290        300
LGTPSAEFMK KLQPTVRNYV ENRPKYPGIK FEELFPDWIF PSESERDKIK TSQARDLLSK
       310        320        330        340        350        360
MLVIDPDKRI SVDEALRHPY ITVWYDPAEA EAPPPQIYDA QLEEREHAIE EWKELIYKEV
       370        380        390        400        410        420
MDWEERSKNG VVKDQPSDAA VSSNATPSQS SSINDISSMS TEQTLASDTD SSLDASTGPL

EGCR         10         20         30         40         50         60
MSDSKCDSQF YSVQVADSTF TVLKRYQQLK PIGSGAQGIV CAAFDTVLGI NVAVKKLSRP
        70         80         90        100        110        120
FQNQTHAKRA YRELVLLKCV NHKNIISLLN VFTPQKTLEE FQDVYLVMEL MDANLCQVIH
       130        140        150        160        170        180
MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTACTNF
       190        200        210        220        230        240
MMTPYVVTRY YRAPEVILGM GYKENVDIWS VGCIMGELVK GCVIFQGTDH IDQWNKVIEQ
       250        260        270        280        290        300
LGTPSAEFMK KLQPTVRNYV ENRPKYPGIK FEELFPDWIF PSESERDKIK TSQARDLLSK
       310        320        330        340        350        360
MLVIDPDKRI SVDEALRHPY ITVWYDPAEA EAPPPQIYDA QLEEREHAIE EWKELIYKEV
       370        380        390        400        410        420
MDWEERSKNG VVKDQPSDAA VSSNATPSQS SSINDISSMS TEQTLASDTD SSLDASTGPL

EGCR

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P45984-1-unknown	MSDSKC...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P45984-1-unknown	MSDSKC...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81204
P45984-1-unknown	MSDSKC...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81205
P45984-1-unknown	MSDSKC...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81206
P45984-1-unknown	MSDSKC...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81207
P45984-227-unknown	GTDHID...	227	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7472
P45984-227-unknown	GTDHID...	227	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5881
P45984-227-unknown	GTDHID...	227	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt147619

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...CVIFQG	226	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7472
...CVIFQG	226	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5881
...CVIFQG	226	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130971
...LEGCR	424	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LEGCR	424	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76824

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	226	IFQG.\|.GTDH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	226	IFQG.\|.GTDH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)