Q15436: Protein transport protein Sec23A {ECO:0000305}

General Information

Protein names	- Protein transport protein Sec23A {ECO:0000305} - hSec23A {ECO:0000303\|PubMed:8898360} - SEC23-related protein A
Gene names	SEC23A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15436

7 N-termini

7 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTTYLEFIQQ NEERDGVRFS WNVWPSSRLE ATRMVVPVAA LFTPLKERPD LPPIQYEPVL
        70         80         90        100        110        120
CSRTTCRAVL NPLCQVDYRA KLWACNFCYQ RNQFPPSYAG ISELNQPAEL LPQFSSIEYV
       130        140        150        160        170        180
VLRGPQMPLI FLYVVDTCME DEDLQALKES MQMSLSLLPP TALVGLITFG RMVQVHELGC
       190        200        210        220        230        240
EGISKSYVFR GTKDLSAKQL QEMLGLSKVP LTQATRGPQV QQPPPSNRFL QPVQKIDMNL
       250        260        270        280        290        300
TDLLGELQRD PWPVPQGKRP LRSSGVALSI AVGLLECTFP NTGARIMMFI GGPATQGPGM
       310        320        330        340        350        360
VVGDELKTPI RSWHDIDKDN AKYVKKGTKH FEALANRAAT TGHVIDIYAC ALDQTGLLEM
       370        380        390        400        410        420
KCCPNLTGGY MVMGDSFNTS LFKQTFQRVF TKDMHGQFKM GFGGTLEIKT SREIKISGAI
       430        440        450        460        470        480
GPCVSLNSKG PCVSENEIGT GGTCQWKICG LSPTTTLAIY FEVVNQHNAP IPQGGRGAIQ
       490        500        510        520        530        540
FVTQYQHSSG QRRIRVTTIA RNWADAQTQI QNIAASFDQE AAAILMARLA IYRAETEEGP
       550        560        570        580        590        600
DVLRWLDRQL IRLCQKFGEY HKDDPSSFRF SETFSLYPQF MFHLRRSSFL QVFNNSPDES
       610        620        630        640        650        660
SYYRHHFMRQ DLTQSLIMIQ PILYAYSFSG PPEPVLLDSS SILADRILLM DTFFQILIYH
       670        680        690        700        710        720
GETIAQWRKS GYQDMPEYEN FRHLLQAPVD DAQEILHSRF PMPRYIDTEH GGSQARFLLS
       730        740        750        760
KVNPSQTHNN MYAWGQESGA PILTDDVSLQ VFMDHLKKLA VSSAA

Isoforms

- Isoform 2 of Protein transport protein Sec23A

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 7 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q15436-2-unknown	MTTYLE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q15436-2-Acetylation	TTYLEF...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q15436-2-Acetylation	TTYLEF...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q15436-2-Acetylation	TTYLEF...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q15436-2-Acetylation	TTYLEF...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q15436-127-unknown	MPLIFL...	127		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000437715
Q15436-203-unknown	MLGLSK...	203		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000444193
Q15436-466-unknown	QHNAPI...	466		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7867
Q15436-627-	SFSGPP...	627			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q15436-687-unknown	APVDDA...	687		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6477

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VPVAAL	40	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000452390
...YQRNQF	93	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000451999
...DTCMED	140	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000451230
...GLITFG	169	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000450819
...FEVVNQ	465	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7867
...RHLLQA	686	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6477
...VSSAA	765	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	465	VVNQ.\|.QHNA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	686	LLQA.\|.APVD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)