P62140: Serine/threonine-protein phosphatase PP1-beta catalytic subunit

General Information

Protein names	- Serine/threonine-protein phosphatase PP1-beta catalytic subunit - PP-1B - PPP1CD - 3.1.3.16 - 3.1.3.53
Gene names	PPP1CB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P62140

5 N-termini

5 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADGELNVDS LITRLLEVRG CRPGKIVQMT EAEVRGLCIK SREIFLSQPI LLELEAPLKI
        70         80         90        100        110        120
CGDIHGQYTD LLRLFEYGGF PPEANYLFLG DYVDRGKQSL ETICLLLAYK IKYPENFFLL
       130        140        150        160        170        180
RGNHECASIN RIYGFYDECK RRFNIKLWKT FTDCFNCLPI AAIVDEKIFC CHGGLSPDLQ
       190        200        210        220        230        240
SMEQIRRIMR PTDVPDTGLL CDLLWSDPDK DVQGWGENDR GVSFTFGADV VSKFLNRHDL
       250        260        270        280        290        300
DLICRAHQVV EDGYEFFAKR QLVTLFSAPN YCGEFDNAGG MMSVDETLMC SFQILKPSEK
       310        320
KAKYQYGGLN SGRPVTPPRT ANPPKKR

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P62140-2-unknown	MADGEL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62140-2-Acetylation	ADGELN...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62140-2-Acetylation	ADGELN...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P62140-2-Acetylation	ADGELN...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P62140-2-Acetylation	ADGELN...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P62140-2-Acetylation	ADGELN...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P62140-29-unknown	MTEAEV...	29		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000390715
P62140-126-unknown	CASINR...	126		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000388056
P62140-311-unknown	SGRPVT...	311		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7632
P62140-311-unknown	SGRPVT...	311		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6107

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RGNHEC	125	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000398839
...GFYDEC	138	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000414918
...DVPDTG	197	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000390715
...YGGLNS	310	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7632
...YGGLNS	310	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6107
...PPKKR	327	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	310	GLNS.\|.SGRP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	310	GLNS.\|.SGRP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)