O00231: 26S proteasome non-ATPase regulatory subunit 11

General Information

Protein names	- 26S proteasome non-ATPase regulatory subunit 11 - 26S proteasome regulatory subunit RPN6 - 26S proteasome regulatory subunit S9 - 26S proteasome regulatory subunit p44.5
Gene names	PSMD11
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O00231

8 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAAAVVEFQ RAQSLLSTDR EASIDILHSI VKRDIQENDE EAVQVKEQSI LELGSLLAKT
        70         80         90        100        110        120
GQAAELGGLL KYVRPFLNSI SKAKAARLVR SLLDLFLDME AATGQEVELC LECIEWAKSE
       130        140        150        160        170        180
KRTFLRQALE ARLVSLYFDT KRYQEALHLG SQLLRELKKM DDKALLVEVQ LLESKTYHAL
       190        200        210        220        230        240
SNLPKARAAL TSARTTANAI YCPPKLQATL DMQSGIIHAA EEKDWKTAYS YFYEAFEGYD
       250        260        270        280        290        300
SIDSPKAITS LKYMLLCKIM LNTPEDVQAL VSGKLALRYA GRQTEALKCV AQASKNRSLA
       310        320        330        340        350        360
DFEKALTDYR AELRDDPIIS THLAKLYDNL LEQNLIRVIE PFSRVQIEHI SSLIKLSKAD
       370        380        390        400        410        420
VERKLSQMIL DKKFHGILDQ GEGVLIIFDE PPVDKTYEAA LETIQNMSKV VDSLYNKAKK

LT

Isoforms

- Isoform 2 of 26S proteasome non-ATPase regulatory subunit 11

Sequence View

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Protein Neighborhood

Domains & Features

8 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O00231-2-unknown	MAAAAV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O00231-1-unknown	MAAAAV...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86364
O00231-2-Acetylation	AAAAVV...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O00231-2-Acetylation	AAAAVV...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O00231-2-Acetylation	AAAAVV...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
O00231-2-Acetylation	AAAAVV...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O00231-2-Acetylation	AAAAVV...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
O00231-2-Acetylation	AAAAVV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111163
O00231-3-acetylation	AAAVVE...	3	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
O00231-3-acetylation	AAAVVE...	3	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
O00231-3-acetylation	AAAVVE...	3	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt163211
O00231-17-unknown	STDREA...	17		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178211
O00231-17-	STDREA...	17			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O00231-213-unknown	QSGIIH...	213		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3245
O00231-213-unknown	QSGIIH...	213		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147111
O00231-263-unknown	TPEDVQ...	263		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5086
O00231-263-unknown	TPEDVQ...	263		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148935

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ATLDMQ	212	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3245
...ATLDMQ	212	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130445
...KIMLNT	262	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5086
...KIMLNT	262	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132315
...AKKLT	422	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...AKKLT	422	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81982

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	212	LDMQ.\|.QSGI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	262	MLNT.\|.TPED	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)