Q9H0L4: Cleavage stimulation factor subunit 2 tau variant

General Information

Protein names	- Cleavage stimulation factor subunit 2 tau variant - CF-1 64 kDa subunit tau variant - Cleavage stimulation factor 64 kDa subunit tau variant - CSTF 64 kDa subunit tau variant - TauCstF-64
Gene names	CSTF2T
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9H0L4

6 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSSLAVRDPA MDRSLRSVFV GNIPYEATEE QLKDIFSEVG SVVSFRLVYD RETGKPKGYG
        70         80         90        100        110        120
FCEYQDQETA LSAMRNLNGR EFSGRALRVD NAASEKNKEE LKSLGPAAPI IDSPYGDPID
       130        140        150        160        170        180
PEDAPESITR AVASLPPEQM FELMKQMKLC VQNSHQEARN MLLQNPQLAY ALLQAQVVMR
       190        200        210        220        230        240
IMDPEIALKI LHRKIHVTPL IPGKSQSVSV SGPGPGPGPG LCPGPNVLLN QQNPPAPQPQ
       250        260        270        280        290        300
HLARRPVKDI PPLMQTPIQG GIPAPGPIPA AVPGAGPGSL TPGGAMQPQL GMPGVGPVPL
       310        320        330        340        350        360
ERGQVQMSDP RAPIPRGPVT PGGLPPRGLL GDAPNDPRGG TLLSVTGEVE PRGYLGPPHQ
       370        380        390        400        410        420
GPPMHHASGH DTRGPSSHEM RGGPLGDPRL LIGEPRGPMI DQRGLPMDGR GGRDSRAMET
       430        440        450        460        470        480
RAMETEVLET RVMERRGMET CAMETRGMEA RGMDARGLEM RGPVPSSRGP MTGGIQGPGP
       490        500        510        520        530        540
INIGAGGPPQ GPRQVPGISG VGNPGAGMQG TGIQGTGMQG AGIQGGGMQG AGIQGVSIQG
       550        560        570        580        590        600
GGIQGGGIQG ASKQGGSQPS SFSPGQSQVT PQDQEKAALI MQVLQLTADQ IAMLPPEQRQ
       610
SILILKEQIQ KSTGAS

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9H0L4-1-unknown	MSSLAV...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9H0L4-11-unknown	MDRSLR...	11	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q9H0L4-103-	SLGPAA...	103		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9H0L4-103-	SLGPAA...	103		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9H0L4-291-	GMPGVG...	291		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9H0L4-291-	GMPGVG...	291		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9H0L4-474-	GIQGPG...	474		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9H0L4-474-	GIQGPG...	474		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9H0L4-540-unknown	GGGIQG...	540	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4249

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...GVSIQG	539	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4249
	...STGAS	616	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	539	SIQG.\|.GGGI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)