P49720: Proteasome subunit beta type-3

General Information

Protein names	- Proteasome subunit beta type-3 - 3.4.25.1 {ECO:0000269\|PubMed:27176742} - Proteasome chain 13 - Proteasome component C10-II - Proteasome theta chain
Gene names	PSMB3
Organism	Homo sapiens
Protease Family
Protease ID	T01.983
Chromosome location
UniProt ID	P49720

4 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSIMSYNGGA VMAMKGKNCV AIAADRRFGI QAQMVTTDFQ KIFPMGDRLY IGLAGLATDV
        70         80         90        100        110        120
QTVAQRLKFR LNLYELKEGR QIKPYTLMSM VANLLYEKRF GPYYTEPVIA GLDPKTFKPF
       130        140        150        160        170        180
ICSLDLIGCP MVTDDFVVSG TCAEQMYGMC ESLWEPNMDP DHLFETISQA MLNAVDRDAV
       190        200
SGMGVIVHII EKDKITTRTL KARMD

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P49720-2-unknown	MSIMSY...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P49720-2-unknown	MSIMSY...	1			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P49720-2-Acetylation	SIMSYN...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P49720-2-Acetylation	SIMSYN...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P49720-2-Acetylation	SIMSYN...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P49720-2-Acetylation	SIMSYN...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P49720-4-unknown	MSYNGG...	4		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000463198
P49720-182-unknown	GMGVIV...	182		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3814

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EQMYGM	148	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463198
...RDAVSG	181	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3814
...KARMD	205	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	181	AVSG.\|.GMGV	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)