Q15717: ELAV-like protein 1

General Information

Protein names	- ELAV-like protein 1 - Hu-antigen R - HuR {ECO:0000303\|PubMed:8626503}
Gene names	ELAVL1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15717

8 N-termini

4 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSNGYEDHMA EDCRGDIGRT NLIVNYLPQN MTQDELRSLF SSIGEVESAK LIRDKVAGHS
        70         80         90        100        110        120
LGYGFVNYVT AKDAERAINT LNGLRLQSKT IKVSYARPSS EVIKDANLYI SGLPRTMTQK
       130        140        150        160        170        180
DVEDMFSRFG RIINSRVLVD QTTGLSRGVA FIRFDKRSEA EEAITSFNGH KPPGSSEPIT
       190        200        210        220        230        240
VKFAANPNQN KNVALLSQLY HSPARRFGGP VHHQAQRFRF SPMGVDHMSG LSGVNVPGNA
       250        260        270        280        290        300
SSGWCIFIYN LGQDADEGIL WQMFGPFGAV TNVKVIRDFN TNKCKGFGFV TMTNYEEAAM
       310        320
AIASLNGYRL GDKILQVSFK TNKSHK

Isoforms

- Isoform 2 of ELAV-like protein 1

Sequence View

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Protein Neighborhood

Domains & Features

8 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q15717-2-unknown	MSNGYE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q15717-2-Acetylation	SNGYED...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q15717-9-unknown	MAEDCR...	9		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q15717-25-unknown	NYLPQN...	25		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6481
Q15717-42-unknown	SIGEVE...	42		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4115
Q15717-42-unknown	SIGEVE...	42		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6482
Q15717-83-unknown	GLRLQS...	83		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000471011
Q15717-169-unknown	GHKPPG...	169		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6483
Q15717-169-	GHKPPG...	169			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TNLIVN	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6481
...RSLFSS	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4115
...RSLFSS	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6482
...ITSFNG	168	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6483
...NKSHK	326	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	24	LIVN.\|.NYLP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	41	LFSS.\|.SIGE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	41	LFSS.\|.SIGE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	168	SFNG.\|.GHKP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)