Q9GZZ9: Ubiquitin-like modifier-activating enzyme 5

General Information

Protein names	- Ubiquitin-like modifier-activating enzyme 5 - Ubiquitin-activating enzyme 5 - ThiFP1 - UFM1-activating enzyme - Ubiquitin-activating enzyme E1 domain-containing protein 1
Gene names	UBA5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9GZZ9

6 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAESVERLQQ RVQELERELA QERSLQVPRS GDGGGGRVRI EKMSSEVVDS NPYSRLMALK
        70         80         90        100        110        120
RMGIVSDYEK IRTFAVAIVG VGGVGSVTAE MLTRCGIGKL LLFDYDKVEL ANMNRLFFQP
       130        140        150        160        170        180
HQAGLSKVQA AEHTLRNINP DVLFEVHNYN ITTVENFQHF MDRISNGGLE EGKPVDLVLS
       190        200        210        220        230        240
CVDNFEARMT INTACNELGQ TWMESGVSEN AVSGHIQLII PGESACFACA PPLVVAANID
       250        260        270        280        290        300
EKTLKREGVC AASLPTTMGV VAGILVQNVL KFLLNFGTVS FYLGYNAMQD FFPTMSMKPN
       310        320        330        340        350        360
PQCDDRNCRK QQEEYKKKVA ALPKQEVIQE EEEIIHEDNE WGIELVSEVS EEELKNFSGP
       370        380        390        400
VPDLPEGITV AYTIPKKQED SVTELTVEDS GESLEDLMAK MKNM

Isoforms

- Isoform 2 of Ubiquitin-like modifier-activating enzyme 5

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9GZZ9-1-unknown	MAESVE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9GZZ9-44-	SSEVVD...	44		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q9GZZ9-57-unknown	MALKRM...	57	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93569
Q9GZZ9-137-unknown	NINPDV...	137	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178167
Q9GZZ9-137-	NINPDV...	137		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9GZZ9-263-unknown	GILVQN...	263	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4247
Q9GZZ9-263-unknown	GILVQN...	263	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt146797

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MGVVAG	262	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4247
...MGVVAG	262	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130120
...KMKNM	404	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KMKNM	404	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89187

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	262	VVAG.\|.GILV	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)