Q12905: Interleukin enhancer-binding factor 2

General Information

Protein names	- Interleukin enhancer-binding factor 2 - Nuclear factor of activated T-cells 45 kDa
Gene names	ILF2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q12905

6 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRGDRGRGRG GRFGSRGGPG GGFRPFVPHI PFDFYLCEMA FPRVKPAPDE TSFSEALLKR
        70         80         90        100        110        120
NQDLAPNSAE QASILSLVTK INNVIDNLIV APGTFEVQIE EVRQVGSYKK GTMTTGHNVA
       130        140        150        160        170        180
DLVVILKILP TLEAVAALGN KVVESLRAQD PSEVLTMLTN ETGFEISSSD ATVKILITTV
       190        200        210        220        230        240
PPNLRKLDPE LHLDIKVLQS ALAAIRHARW FEENASQSTV KVLIRLLKDL RIRFPGFEPL
       250        260        270        280        290        300
TPWILDLLGH YAVMNNPTRQ PLALNVAYRR CLQILAAGLF LPGSVGITDP CESGNFRVHT
       310        320        330        340        350        360
VMTLEQQDMV CYTAQTLVRI LSHGGFRKIL GQEGDASYLA SEISTWDGVI VTPSEKAYEK
       370        380        390
PPEKKEGEEE EENTEEPPQG EEEESMETQE

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q12905-1-unknown	MRGDRG...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q12905-39-unknown	MAFPRV...	39	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000357673
Q12905-166-unknown	ISSSDA...	166	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6259
Q12905-284-unknown	SVGITD...	284	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3972
Q12905-287-unknown	ITDPCE...	287	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6260
Q12905-287-unknown	ITDPCE...	287	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3973
Q12905-348-	GVIVTP...	348		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QDPSEV	153	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000357673
...ETGFEI	165	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6259
...LFLPGS	283	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3972
...PGSVGI	286	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6260
...PGSVGI	286	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3973
...METQE	390	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	165	GFEI.\|.ISSS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	283	LPGS.\|.SVGI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	286	SVGI.\|.ITDP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	286	SVGI.\|.ITDP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)