Q8IWZ8: SURP and G-patch domain-containing protein 1

General Information

Protein names	- SURP and G-patch domain-containing protein 1 - RNA-binding protein RBP - Splicing factor 4
Gene names	SUGP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8IWZ8

7 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSLKMDNRDV AGKANRWFGV APPKSGKMNM NILHQEELIA QKKREIEAKM EQKAKQNQVA
        70         80         90        100        110        120
SPQPPHPGEI TNAHNSSCIS NKFANDGSFL QQFLKLQKAQ TSTDAPTSAP SAPPSTPTPS
       130        140        150        160        170        180
AGKRSLLISR RTGLGLASLP GPVKSYSHAK QLPVAHRPSV FQSPDEDEEE DYEQWLEIKV
       190        200        210        220        230        240
SPPEGAETRK VIEKLARFVA EGGPELEKVA MEDYKDNPAF AFLHDKNSRE FLYYRKKVAE
       250        260        270        280        290        300
IRKEAQKSQA ASQKVSPPED EEVKNLAEKL ARFIADGGPE VETIALQNNR ENQAFSFLYE
       310        320        330        340        350        360
PNSQGYKYYR QKLEEFRKAK ASSTGSFTAP DPGLKRKSPP EALSGSLPPA TTCPASSTPA
       370        380        390        400        410        420
PTIIPAPAAP GKPASAATVK RKRKSRWGPE EDKVELPPAE LVQRDVDASP SPLSVQDLKG
       430        440        450        460        470        480
LGYEKGKPVG LVGVTELSDA QKKQLKEQQE MQQMYDMIMQ HKRAMQDMQL LWEKAVQQHQ
       490        500        510        520        530        540
HGYDSDEEVD SELGTWEHQL RRMEMDKTRE WAEQLTKMGR GKHFIGDFLP PDELEKFMET
       550        560        570        580        590        600
FKALKEGREP DYSEYKEFKL TVENIGYQML MKMGWKEGEG LGSEGQGIKN PVNKGTTTVD
       610        620        630        640
GAGFGIDRPA ELSKEDDEYE AFRKRMMLAY RFRPNPLNNP RRPYY

Isoforms

- Isoform 2 of SURP and G-patch domain-containing protein 1

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

7 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8IWZ8-1-unknown	MSLKMD...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8IWZ8-1-unknown	MSLKMD...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt91054
Q8IWZ8-5-unknown	MDNRDV...	5	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q8IWZ8-5-unknown	MDNRDV...	5	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt194635
Q8IWZ8-107-	TSAPSA...	107		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q8IWZ8-107-	TSAPSA...	107		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q8IWZ8-107-unknown	TSAPSA...	107	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt167575
Q8IWZ8-138-unknown	SLPGPV...	138	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt167573
Q8IWZ8-138-	SLPGPV...	138		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q8IWZ8-431-unknown	LVGVTE...	431	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4155

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...GKPVGL	430	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4155
	...RRPYY	645	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	430	PVGL.\|.LVGV	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)