P35250: Replication factor C subunit 2

General Information

Protein names	- Replication factor C subunit 2 - Activator 1 40 kDa subunit - A1 40 kDa subunit - Activator 1 subunit 2 - Replication factor C 40 kDa subunit - RF-C 40 kDa subunit - RFC40
Gene names	RFC2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P35250

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEVEAVCGGA GEVEAQDSDP APAFSKAPGS AGHYELPWVE KYRPVKLNEI VGNEDTVSRL
        70         80         90        100        110        120
EVFAREGNVP NIIIAGPPGT GKTTSILCLA RALLGPALKD AMLELNASND RGIDVVRNKI
       130        140        150        160        170        180
KMFAQQKVTL PKGRHKIIIL DEADSMTDGA QQALRRTMEI YSKTTRFALA CNASDKIIEP
       190        200        210        220        230        240
IQSRCAVLRY TKLTDAQILT RLMNVIEKER VPYTDDGLEA IIFTAQGDMR QALNNLQSTF
       250        260        270        280        290        300
SGFGFINSEN VFKVCDEPHP LLVKEMIQHC VNANIDEAYK ILAHLWHLGY SPEDIIGNIF
       310        320        330        340        350
RVCKTFQMAE YLKLEFIKEI GYTHMKIAEG VNSLLQMAGL LARLCQKTMA PVAS

Isoforms

- Isoform 2 of Replication factor C subunit 2

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
P35250-1-unknown	MEVEAV...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87330
P35250-1-Acetylation	MEVEAV...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P35250-1-Acetylation	MEVEAV...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P35250-1-Acetylation	MEVEAV...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt103075
P35250-245-unknown	FINSEN...	245		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3776
P35250-245-unknown	FINSEN...	245		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147018

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...FSGFGF	244	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3776
...FSGFGF	244	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt130351
...APVAS	354	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...APVAS	354	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt82948
...APVAS	354		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...APVAS	354		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...APVAS	354		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...APVAS	354		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	244	GFGF.\|.FINS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)