Q13642: Four and a half LIM domains protein 1

General Information

Protein names	- Four and a half LIM domains protein 1 - FHL-1 - Skeletal muscle LIM-protein 1 - SLIM - SLIM-1
Gene names	FHL1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13642

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 1 of Four and a half LIM domains protein 1 - Isoform 3 of Four and a half LIM domains protein 1 - Isoform 4 of Four and a half LIM domains protein 1 - Isoform 5 of Four and a half LIM domains protein 1

Sequence View

        10         20         30         40         50         60
MAEKFDCHYC RDPLQGKKYV QKDGHHCCLK CFDKFCANTC VECRKPIGAD SKEVHYKNRF
        70         80         90        100        110        120
WHDTCFRCAK CLHPLANETF VAKDNKILCN KCTTREDSPK CKGCFKAIVA GDQNVEYKGT
       130        140        150        160        170        180
VWHKDCFTCS NCKQVIGTGS FFPKGEDFYC VTCHETKFAK HCVKCNKAIT SGGITYQDQP
       190        200        210        220        230        240
WHADCFVCVT CSKKLAGQRF TAVEDQYYCV DCYKNFVAKK CAGCKNPITG KRTVSRVSHP
       250        260        270        280        290        300
VSKARKPPVC HGKRLPLTLF PSANLRGRHP GGERTCPSWV VVLYRKNRSL AAPRGPGLVK
       310        320
APVWWPMKDN PGTTTASTAK NAP         10         20         30         40         50         60
MAEKFDCHYC RDPLQGKKYV QKDGHHCCLK CFDKFCANTC VECRKPIGAD SKEVHYKNRF
        70         80         90        100        110        120
WHDTCFRCAK CLHPLANETF VAKDNKILCN KCTTREDSPK CKGCFKAIVA GDQNVEYKGT
       130        140        150        160        170        180
VWHKDCFTCS NCKQVIGTGS FFPKGEDFYC VTCHETKFAK HCVKCNKAIT SGGITYQDQP
       190        200        210        220        230        240
WHADCFVCVT CSKKLAGQRF TAVEDQYYCV DCYKNFVAKK CAGCKNPITG KRTVSRVSHP
       250        260        270        280        290        300
VSKARKPPVC HGKRLPLTLF PSANLRGRHP GGERTCPSWV VVLYRKNRSL AAPRGPGLVK
       310        320
APVWWPMKDN PGTTTASTAK NAP         10         20         30         40         50         60
MAEKFDCHYC RDPLQGKKYV QKDGHHCCLK CFDKFCANTC VECRKPIGAD SKEVHYKNRF
        70         80         90        100        110        120
WHDTCFRCAK CLHPLANETF VAKDNKILCN KCTTREDSPK CKGCFKAIVA GDQNVEYKGT
       130        140        150        160        170        180
VWHKDCFTCS NCKQVIGTGS FFPKGEDFYC VTCHETKFAK HCVKCNKAIT SGGITYQDQP
       190        200        210        220        230        240
WHADCFVCVT CSKKLAGQRF TAVEDQYYCV DCYKNFVAKK CAGCKNPITG KRTVSRVSHP
       250        260        270        280        290        300
VSKARKPPVC HGKRLPLTLF PSANLRGRHP GGERTCPSWV VVLYRKNRSL AAPRGPGLVK
       310        320
APVWWPMKDN PGTTTASTAK NAP         10         20         30         40         50         60
MAEKFDCHYC RDPLQGKKYV QKDGHHCCLK CFDKFCANTC VECRKPIGAD SKEVHYKNRF
        70         80         90        100        110        120
WHDTCFRCAK CLHPLANETF VAKDNKILCN KCTTREDSPK CKGCFKAIVA GDQNVEYKGT
       130        140        150        160        170        180
VWHKDCFTCS NCKQVIGTGS FFPKGEDFYC VTCHETKFAK HCVKCNKAIT SGGITYQDQP
       190        200        210        220        230        240
WHADCFVCVT CSKKLAGQRF TAVEDQYYCV DCYKNFVAKK CAGCKNPITG KRTVSRVSHP
       250        260        270        280        290        300
VSKARKPPVC HGKRLPLTLF PSANLRGRHP GGERTCPSWV VVLYRKNRSL AAPRGPGLVK
       310        320
APVWWPMKDN PGTTTASTAK NAP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q13642-1-unknown	MAEKFD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75173
Q13642-1-unknown	MAEKFD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105060
Q13642-1-unknown	MAEKFD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105061
Q13642-2-unknown	AEKFDC...	2	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q13642-2-unknown	AEKFDC...	2	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111482
Q13642-2-unknown	AEKFDC...	2	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111480
Q13642-2-unknown	AEKFDC...	2	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111481
Q13642-135-unknown	VIGTGS...	135	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3997
Q13642-135-unknown	VIGTGS...	135	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt144086
Q13642-135-unknown	VIGTGS...	135	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt144790
Q13642-135-unknown	VIGTGS...	135	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt145309

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SNCKQV	134	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3997
...SNCKQV	134	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127337
...SNCKQV	134	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128065
...SNCKQV	134	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128600
...AKNAP	323	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...AKNAP	323	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70791

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	134	CKQV.\|.VIGT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)