P15927: Replication protein A 32 kDa subunit

General Information

Protein names	- Replication protein A 32 kDa subunit - RP-A p32 - Replication factor A protein 2 - RF-A protein 2 - Replication protein A 34 kDa subunit - RP-A p34
Gene names	RPA2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P15927

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Replication protein A 32 kDa subunit - Isoform 3 of Replication protein A 32 kDa subunit

Sequence View

        10         20         30         40         50         60
MWNSGFESYG SSSYGGAGGY TQSPGGFGSP APSQAEKKSR ARAQHIVPCT ISQLLSATLV
        70         80         90        100        110        120
DEVFRIGNVE ISQVTIVGII RHAEKAPTNI VYKIDDMTAA PMDVRQWVDT DDTSSENTVV
       130        140        150        160        170        180
PPETYVKVAG HLRSFQNKKS LVAFKIMPLE DMNEFTTHIL EVINAHMVLS KANSQPSAGR
       190        200        210        220        230        240
APISNPGMSE AGNFGGNSFM PANGLTVAQN QVLNLIKACP RPEGLNFQDL KNQLKHMSVS
       250        260        270
SIKQAVDFLS NEGHIYSTVD DDHFKSTDAE         10         20         30         40         50         60
MWNSGFESYG SSSYGGAGGY TQSPGGFGSP APSQAEKKSR ARAQHIVPCT ISQLLSATLV
        70         80         90        100        110        120
DEVFRIGNVE ISQVTIVGII RHAEKAPTNI VYKIDDMTAA PMDVRQWVDT DDTSSENTVV
       130        140        150        160        170        180
PPETYVKVAG HLRSFQNKKS LVAFKIMPLE DMNEFTTHIL EVINAHMVLS KANSQPSAGR
       190        200        210        220        230        240
APISNPGMSE AGNFGGNSFM PANGLTVAQN QVLNLIKACP RPEGLNFQDL KNQLKHMSVS
       250        260        270
SIKQAVDFLS NEGHIYSTVD DDHFKSTDAE

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Directness:

Physiological Relevance:

Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P15927-1-Acetylation	MWNSGF...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P15927-19-unknown	GYTQSP...	19		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178096
P15927-19-unknown	GYTQSP...	19		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178095
P15927-19-	GYTQSP...	19			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P15927-23-unknown	SPGGFG...	23		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3657
P15927-23-unknown	SPGGFG...	23		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt137603
P15927-23-unknown	SPGGFG...	23		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142988

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GGYTQS	22	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3657
...STDAE	270	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...STDAE	270	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82944
...STDAE	270	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82945

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	22	YTQS.\|.SPGG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)