Q14651: Plastin-1

General Information

Protein names	- Plastin-1 - Intestine-specific plastin - I-plastin
Gene names	PLS1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q14651

3 N-termini

9 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MENSTTTISR EELEELQEAF NKIDIDNSGY VSDYELQDLF KEASLPLPGY KVREIVEKIL
        70         80         90        100        110        120
SVADSNKDGK ISFEEFVSLM QELKSKDISK TFRKIINKRE GITAIGGTST ISSEGTQHSY
       130        140        150        160        170        180
SEEEKVAFVN WINKALENDP DCKHLIPMNP NDDSLFKSLA DGILLCKMIN LSEPDTIDER
       190        200        210        220        230        240
AINKKKLTPF TISENLNLAL NSASAIGCTV VNIGASDLKE GKPHLVLGLL WQIIKVGLFA
       250        260        270        280        290        300
DIEISRNEAL IALLNEGEEL EELMKLSPEE LLLRWVNYHL TNAGWHTISN FSQDIKDSRA
       310        320        330        340        350        360
YFHLLNQIAP KGGEDGPAIA IDLSGINETN DLKRAGLMLQ EADKLGCKQF VTPADVVSGN
       370        380        390        400        410        420
PKLNLAFVAN LFNTYPCLHK PNNNDIDMNL LEGESKEERT FRNWMNSLGV NPYINHLYSD
       430        440        450        460        470        480
LADALVIFQL YEMIRVPVNW SHVNKPPYPA LGGNMKKIEN CNYAVELGKN KAKFSLVGIA
       490        500        510        520        530        540
GQDLNEGNST LTLALVWQLM RRYTLNVLSD LGEGEKVNDE IIIKWVNQTL KSANKKTSIS
       550        560        570        580        590        600
SFKDKSISTS LPVLDLIDAI APNAVRQEMI RRENLSDEDK LNNAKYAISV ARKIGARIYA
       610        620
LPDDLVEVKP KMVMTVFACL MGKGLNRIK

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 9 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q14651-1-Acetylation	MENSTT...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q14651-1-Acetylation	MENSTT...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q14651-1-Acetylation	MENSTT...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q14651-1-Acetylation	MENSTT...	1	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q14651-80-unknown	MQELKS...	80		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000417481
Q14651-111-unknown	ISSEGT...	111		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4053

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GYVSDY	33	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000419893
...PGYKVR	52	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417491
...YKVREI	54	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000419271
...EIVEKI	58	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000419531
...GGTSTI	110	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4053
...GTQHSY	119	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417311
...TQHSYS	120	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000418880
...EADKLG	345	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417481
...LNRIK	629	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	110	TSTI.\|.ISSE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)