Q9NZM4: BRD4-interacting chromatin-remodeling complex-associated protein {ECO:0000305}
Protein names | - BRD4-interacting chromatin-remodeling complex-associated protein {ECO:0000305} - Glioma tumor suppressor candidate region gene 1 protein {ECO:0000312|HGNC:HGNC:4332} |
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Gene names | GLTSCR1 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9NZM4 |
3
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MDDEDGRCLL DVICDPQALN DFLHGSEKLD SDDLLDNPGE AQSAFYEGPG LHVQEASGNH
70 80 90 100 110 120
LNPEPNQPAP SVDLDFLEDD ILGSPATGGG GGGSGGADQP CDILQQSLQE ANITEQTLEA
130 140 150 160 170 180
EAELDLGPFQ LPTLQPADGG AGPTGAGGAA AVAAGPQALF PGSTDLLGLQ GPPTVLTHQA
190 200 210 220 230 240
LVPPQDVVNK ALSVQPFLQP VGLGNVTLQP IPGLQGLPNG SPGGATAATL GLAPIQVVGQ
250 260 270 280 290 300
PVMALNTPTS QLLAKQVPVS GYLASAAGPS EPVTLASAGV SPQGAGLVIQ KNLSAAVATT
310 320 330 340 350 360
LNGNSVFGGA GAASAPTGTP SGQPLAVAPG LGSSPLVPAP NVILHRTPTP IQPKPAGVLP
370 380 390 400 410 420
PKLYQLTPKP FAPAGATLTI QGEPGALPQQ PKAPQNLTFM AAGKAGQNVV LSGFPAPALQ
430 440 450 460 470 480
ANVFKQPPAT TTGAAPPQPP GALSKPMSVH LLNQGSSIVI PAQHMLPGQN QFLLPGAPAV
490 500 510 520 530 540
QLPQQLSALP ANVGGQILAA AAPHTGGQLI ANPILTNQNL AGPLSLGPVL APHSGAHSAH
550 560 570 580 590 600
ILSAAPIQVG QPALFQMPVS LAAGSLPTQS QPAPAGPAAT TVLQGVTLPP SAVAMLNTPD
610 620 630 640 650 660
GLVQPATPAA ATGEAAPVLT VQPAPQAPPA VSTPLPLGLQ QPQAQQPPQA PTPQAAAPPQ
670 680 690 700 710 720
ATTPQPSPGL ASSPEKIVLG QPPSATPTAI LTQDSLQMFL PQERSQQPLS AEGPHLSVPA
730 740 750 760 770 780
SVIVSAPPPA QDPAPATPVA KGAGLGPQAP DSQASPAPAP QIPAAAPLKG PGPSSSPSLP
790 800 810 820 830 840
HQAPLGDSPH LPSPHPTRPP SRPPSRPQSV SRPPSEPPLH PCPPPQAPPT LPGIFVIQNQ
850 860 870 880 890 900
LGVPPPASNP APTAPGPPQP PLRPQSQPPE GPLPPAPHLP PSSTSSAVAS SSETSSRLPA
910 920 930 940 950 960
PTPSDFQLQF PPSQGPHKSP TPPPTLHLVP EPAAPPPPPP RTFQMVTTPF PALPQPKALL
970 980 990 1000 1010 1020
ERFHQVPSGI ILQNKAGGAP AAPQTSTSLG PLTSPAASVL VSGQAPSGTP TAPSHAPAPA
1030 1040 1050 1060 1070 1080
PMAATGLPPL LPAENKAFAS NLPTLNVAKA ASSGPGKPSG LQYESKLSGL KKPPTLQPSK
1090 1100 1110 1120 1130 1140
EACFLEHLHK HQGSVLHPDY KTAFPSFEDA LHRLLPYHVY QGALPSPSDY HKVDEEFETV
1150 1160 1170 1180 1190 1200
STQLLKRTQA MLNKYRLLLL EESRRVSPSA EMVMIDRMFI QEEKTTLALD KQLAKEKPDE
1210 1220 1230 1240 1250 1260
YVSSSRSLGL PIAASSEGHR LPGHGPLSSS APGASTQPPP HLPTKLVIRH GGAGGSPSVT
1270 1280 1290 1300 1310 1320
WARASSSLSS SSSSSSAASS LDADEDGPMP SRNRPPIKTY EARSRIGLKL KIKQEAGLSK
1330 1340 1350 1360 1370 1380
VVHNTALDPV HQPPPPPATL KVAEPPPRPP PPPPPTGQMN GTVDHPPPAA PERKPLGTAP
1390 1400 1410 1420 1430 1440
HCPRLPLRKT YRENVGGPGA PEGTPAGRAR GGSPAPLPAK VDEATSGLIR ELAAVEDELY
1450 1460 1470 1480 1490 1500
QRMLKGPPPE PAASAAQGTG DPDWEAPGLP PAKRRKSESP DVDQASFSSD SPQDDTLTEH
1510 1520 1530 1540 1550 1560
LQSAIDSILN LQQAPGRTPA PSYPHAASAG TPASPPPLHR PEAYPPSSHN GGLGARTLTR
Isoforms
- Isoform 2 of Glioma tumor suppressor candidate region gene 1 protein - Isoform 2 of BRD4-interacting chromatin-remodeling complex-associated proteinSequence View
10 20 30 40 50 60
MDDEDGRCLL DVICDPQALN DFLHGSEKLD SDDLLDNPGE AQSAFYEGPG LHVQEASGNH
70 80 90 100 110 120
LNPEPNQPAP SVDLDFLEDD ILGSPATGGG GGGSGGADQP CDILQQSLQE ANITEQTLEA
130 140 150 160 170 180
EAELDLGPFQ LPTLQPADGG AGPTGAGGAA AVAAGPQALF PGSTDLLGLQ GPPTVLTHQA
190 200 210 220 230 240
LVPPQDVVNK ALSVQPFLQP VGLGNVTLQP IPGLQGLPNG SPGGATAATL GLAPIQVVGQ
250 260 270 280 290 300
PVMALNTPTS QLLAKQVPVS GYLASAAGPS EPVTLASAGV SPQGAGLVIQ KNLSAAVATT
310 320 330 340 350 360
LNGNSVFGGA GAASAPTGTP SGQPLAVAPG LGSSPLVPAP NVILHRTPTP IQPKPAGVLP
370 380 390 400 410 420
PKLYQLTPKP FAPAGATLTI QGEPGALPQQ PKAPQNLTFM AAGKAGQNVV LSGFPAPALQ
430 440 450 460 470 480
ANVFKQPPAT TTGAAPPQPP GALSKPMSVH LLNQGSSIVI PAQHMLPGQN QFLLPGAPAV
490 500 510 520 530 540
QLPQQLSALP ANVGGQILAA AAPHTGGQLI ANPILTNQNL AGPLSLGPVL APHSGAHSAH
550 560 570 580 590 600
ILSAAPIQVG QPALFQMPVS LAAGSLPTQS QPAPAGPAAT TVLQGVTLPP SAVAMLNTPD
610 620 630 640 650 660
GLVQPATPAA ATGEAAPVLT VQPAPQAPPA VSTPLPLGLQ QPQAQQPPQA PTPQAAAPPQ
670 680 690 700 710 720
ATTPQPSPGL ASSPEKIVLG QPPSATPTAI LTQDSLQMFL PQERSQQPLS AEGPHLSVPA
730 740 750 760 770 780
SVIVSAPPPA QDPAPATPVA KGAGLGPQAP DSQASPAPAP QIPAAAPLKG PGPSSSPSLP
790 800 810 820 830 840
HQAPLGDSPH LPSPHPTRPP SRPPSRPQSV SRPPSEPPLH PCPPPQAPPT LPGIFVIQNQ
850 860 870 880 890 900
LGVPPPASNP APTAPGPPQP PLRPQSQPPE GPLPPAPHLP PSSTSSAVAS SSETSSRLPA
910 920 930 940 950 960
PTPSDFQLQF PPSQGPHKSP TPPPTLHLVP EPAAPPPPPP RTFQMVTTPF PALPQPKALL
970 980 990 1000 1010 1020
ERFHQVPSGI ILQNKAGGAP AAPQTSTSLG PLTSPAASVL VSGQAPSGTP TAPSHAPAPA
1030 1040 1050 1060 1070 1080
PMAATGLPPL LPAENKAFAS NLPTLNVAKA ASSGPGKPSG LQYESKLSGL KKPPTLQPSK
1090 1100 1110 1120 1130 1140
EACFLEHLHK HQGSVLHPDY KTAFPSFEDA LHRLLPYHVY QGALPSPSDY HKVDEEFETV
1150 1160 1170 1180 1190 1200
STQLLKRTQA MLNKYRLLLL EESRRVSPSA EMVMIDRMFI QEEKTTLALD KQLAKEKPDE
1210 1220 1230 1240 1250 1260
YVSSSRSLGL PIAASSEGHR LPGHGPLSSS APGASTQPPP HLPTKLVIRH GGAGGSPSVT
1270 1280 1290 1300 1310 1320
WARASSSLSS SSSSSSAASS LDADEDGPMP SRNRPPIKTY EARSRIGLKL KIKQEAGLSK
1330 1340 1350 1360 1370 1380
VVHNTALDPV HQPPPPPATL KVAEPPPRPP PPPPPTGQMN GTVDHPPPAA PERKPLGTAP
1390 1400 1410 1420 1430 1440
HCPRLPLRKT YRENVGGPGA PEGTPAGRAR GGSPAPLPAK VDEATSGLIR ELAAVEDELY
1450 1460 1470 1480 1490 1500
QRMLKGPPPE PAASAAQGTG DPDWEAPGLP PAKRRKSESP DVDQASFSSD SPQDDTLTEH
1510 1520 1530 1540 1550 1560
LQSAIDSILN LQQAPGRTPA PSYPHAASAG TPASPPPLHR PEAYPPSSHN GGLGARTLTR
10 20 30 40 50 60
MDDEDGRCLL DVICDPQALN DFLHGSEKLD SDDLLDNPGE AQSAFYEGPG LHVQEASGNH
70 80 90 100 110 120
LNPEPNQPAP SVDLDFLEDD ILGSPATGGG GGGSGGADQP CDILQQSLQE ANITEQTLEA
130 140 150 160 170 180
EAELDLGPFQ LPTLQPADGG AGPTGAGGAA AVAAGPQALF PGSTDLLGLQ GPPTVLTHQA
190 200 210 220 230 240
LVPPQDVVNK ALSVQPFLQP VGLGNVTLQP IPGLQGLPNG SPGGATAATL GLAPIQVVGQ
250 260 270 280 290 300
PVMALNTPTS QLLAKQVPVS GYLASAAGPS EPVTLASAGV SPQGAGLVIQ KNLSAAVATT
310 320 330 340 350 360
LNGNSVFGGA GAASAPTGTP SGQPLAVAPG LGSSPLVPAP NVILHRTPTP IQPKPAGVLP
370 380 390 400 410 420
PKLYQLTPKP FAPAGATLTI QGEPGALPQQ PKAPQNLTFM AAGKAGQNVV LSGFPAPALQ
430 440 450 460 470 480
ANVFKQPPAT TTGAAPPQPP GALSKPMSVH LLNQGSSIVI PAQHMLPGQN QFLLPGAPAV
490 500 510 520 530 540
QLPQQLSALP ANVGGQILAA AAPHTGGQLI ANPILTNQNL AGPLSLGPVL APHSGAHSAH
550 560 570 580 590 600
ILSAAPIQVG QPALFQMPVS LAAGSLPTQS QPAPAGPAAT TVLQGVTLPP SAVAMLNTPD
610 620 630 640 650 660
GLVQPATPAA ATGEAAPVLT VQPAPQAPPA VSTPLPLGLQ QPQAQQPPQA PTPQAAAPPQ
670 680 690 700 710 720
ATTPQPSPGL ASSPEKIVLG QPPSATPTAI LTQDSLQMFL PQERSQQPLS AEGPHLSVPA
730 740 750 760 770 780
SVIVSAPPPA QDPAPATPVA KGAGLGPQAP DSQASPAPAP QIPAAAPLKG PGPSSSPSLP
790 800 810 820 830 840
HQAPLGDSPH LPSPHPTRPP SRPPSRPQSV SRPPSEPPLH PCPPPQAPPT LPGIFVIQNQ
850 860 870 880 890 900
LGVPPPASNP APTAPGPPQP PLRPQSQPPE GPLPPAPHLP PSSTSSAVAS SSETSSRLPA
910 920 930 940 950 960
PTPSDFQLQF PPSQGPHKSP TPPPTLHLVP EPAAPPPPPP RTFQMVTTPF PALPQPKALL
970 980 990 1000 1010 1020
ERFHQVPSGI ILQNKAGGAP AAPQTSTSLG PLTSPAASVL VSGQAPSGTP TAPSHAPAPA
1030 1040 1050 1060 1070 1080
PMAATGLPPL LPAENKAFAS NLPTLNVAKA ASSGPGKPSG LQYESKLSGL KKPPTLQPSK
1090 1100 1110 1120 1130 1140
EACFLEHLHK HQGSVLHPDY KTAFPSFEDA LHRLLPYHVY QGALPSPSDY HKVDEEFETV
1150 1160 1170 1180 1190 1200
STQLLKRTQA MLNKYRLLLL EESRRVSPSA EMVMIDRMFI QEEKTTLALD KQLAKEKPDE
1210 1220 1230 1240 1250 1260
YVSSSRSLGL PIAASSEGHR LPGHGPLSSS APGASTQPPP HLPTKLVIRH GGAGGSPSVT
1270 1280 1290 1300 1310 1320
WARASSSLSS SSSSSSAASS LDADEDGPMP SRNRPPIKTY EARSRIGLKL KIKQEAGLSK
1330 1340 1350 1360 1370 1380
VVHNTALDPV HQPPPPPATL KVAEPPPRPP PPPPPTGQMN GTVDHPPPAA PERKPLGTAP
1390 1400 1410 1420 1430 1440
HCPRLPLRKT YRENVGGPGA PEGTPAGRAR GGSPAPLPAK VDEATSGLIR ELAAVEDELY
1450 1460 1470 1480 1490 1500
QRMLKGPPPE PAASAAQGTG DPDWEAPGLP PAKRRKSESP DVDQASFSSD SPQDDTLTEH
1510 1520 1530 1540 1550 1560
LQSAIDSILN LQQAPGRTPA PSYPHAASAG TPASPPPLHR PEAYPPSSHN GGLGARTLTR
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9NZM4-1-unknown | MDDEDG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9NZM4-243-unknown | MALNTP... | 243 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt76548 | |||
Q9NZM4-927-unknown | HLVPEP... | 927 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4270 | |||
Q9NZM4-927-unknown | HLVPEP... | 927 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt155703 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...PPPTLH | 926 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4270 | |||
...PPPTLH | 926 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139149 | |||
...RTLTR | 1560 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...RTLTR | 1560 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt72166 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATB_HUMAN | 926 | PTLH.|.HLVP | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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