Q9Y4C2: TRPM8 channel-associated factor 1 {ECO:0000303|PubMed:25559186}

General Information

Protein names	- TRPM8 channel-associated factor 1 {ECO:0000303\|PubMed:25559186} - TRP channel-associated factor 1 {ECO:0000303\|PubMed:25559186}
Gene names	FAM115A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y4C2

2 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATPSAAFEA LMNGVTSWDV PEDAVPCELL LIGEASFPVM VNDMGQVLIA ASSYGRGRLV
        70         80         90        100        110        120
VVSHEDYLVE AQLTPFLLNA VGWLCSSPGA PIGVHPSLAP LAKILEGSGV DAKVEPEVKD
       130        140        150        160        170        180
SLGVYCIDAY NETMTEKLVK FMKCGGGLLI GGQAWDWANQ GEDERVLFTF PGNLVTSVAG
       190        200        210        220        230        240
IYFTDNKGDT SFFKVSKKMP KIPVLVSCED DLSDDREELL HGISELDISN SDCFPSQLLV
       250        260        270        280        290        300
HGALAFPLGL DSYHGCVIAA ARYGRGRVVV TGHKVLFTVG KLGPFLLNAV RWLDGGRRGK
       310        320        330        340        350        360
VVVQTELRTL SGLLAVGGID TSIEPNLTSD ASVYCFEPVS EVGVKELQEF VAEGGGLFVG
       370        380        390        400        410        420
AQAWWWAFKN PGVSPLARFP GNLLLNPFGI SITSQSLNPG PFRTPKAGIR TYHFRSTLAE
       430        440        450        460        470        480
FQVIMGRKRG NVEKGWLAKL GPDGAAFLQI PAEEIPAYMS VHRLLRKLLS RYRLPVATRE
       490        500        510        520        530        540
NPVINDCCRG AMLSLATGLA HSGSDLSLLV PEIEDMYSSP YLRPSESPIT VEVNCTNPGT
       550        560        570        580        590        600
RYCWMSTGLY IPGRQIIEVS LPEAAASADL KIQIGCHTDD LTRASKLFRG PLVINRCCLD
       610        620        630        640        650        660
KPTKSITCLW GGLLYIIVPQ NSKLGSVPVT VKGAVHAPYY KLGETTLEEW KRRIQENPGP
       670        680        690        700        710        720
WGELATDNII LTVPTANLRT LENPEPLLRL WDEVMQAVAR LGAEPFPLRL PQRIVADVQI
       730        740        750        760        770        780
SVGWMHAGYP IMCHLESVQE LINEKLIRTK GLWGPVHELG RNQQRQEWEF PPHTTEATCN
       790        800        810        820        830        840
LWCVYVHETV LGIPRSRANI ALWPPVREKR VRIYLSKGPN VKNWNAWTAL ETYLQLQEAF
       850        860        870        880        890        900
GWEPFIRLFT EYRNQTNLPT ENVDKMNLWV KMFSHQVQKN LAPFFEAWAW PIQKEVATSL
       910        920
AYLPEWKENI MKLYLLTQMP H

Isoforms

- Isoform 2 of Protein FAM115A - Isoform 2 of TRPM8 channel-associated factor 1

Sequence View

        10         20         30         40         50         60
MATPSAAFEA LMNGVTSWDV PEDAVPCELL LIGEASFPVM VNDMGQVLIA ASSYGRGRLV
        70         80         90        100        110        120
VVSHEDYLVE AQLTPFLLNA VGWLCSSPGA PIGVHPSLAP LAKILEGSGV DAKVEPEVKD
       130        140        150        160        170        180
SLGVYCIDAY NETMTEKLVK FMKCGGGLLI GGQAWDWANQ GEDERVLFTF PGNLVTSVAG
       190        200        210        220        230        240
IYFTDNKGDT SFFKVSKKMP KIPVLVSCED DLSDDREELL HGISELDISN SDCFPSQLLV
       250        260        270        280        290        300
HGALAFPLGL DSYHGCVIAA ARYGRGRVVV TGHKVLFTVG KLGPFLLNAV RWLDGGRRGK
       310        320        330        340        350        360
VVVQTELRTL SGLLAVGGID TSIEPNLTSD ASVYCFEPVS EVGVKELQEF VAEGGGLFVG
       370        380        390        400        410        420
AQAWWWAFKN PGVSPLARFP GNLLLNPFGI SITSQSLNPG PFRTPKAGIR TYHFRSTLAE
       430        440        450        460        470        480
FQVIMGRKRG NVEKGWLAKL GPDGAAFLQI PAEEIPAYMS VHRLLRKLLS RYRLPVATRE
       490        500        510        520        530        540
NPVINDCCRG AMLSLATGLA HSGSDLSLLV PEIEDMYSSP YLRPSESPIT VEVNCTNPGT
       550        560        570        580        590        600
RYCWMSTGLY IPGRQIIEVS LPEAAASADL KIQIGCHTDD LTRASKLFRG PLVINRCCLD
       610        620        630        640        650        660
KPTKSITCLW GGLLYIIVPQ NSKLGSVPVT VKGAVHAPYY KLGETTLEEW KRRIQENPGP
       670        680        690        700        710        720
WGELATDNII LTVPTANLRT LENPEPLLRL WDEVMQAVAR LGAEPFPLRL PQRIVADVQI
       730        740        750        760        770        780
SVGWMHAGYP IMCHLESVQE LINEKLIRTK GLWGPVHELG RNQQRQEWEF PPHTTEATCN
       790        800        810        820        830        840
LWCVYVHETV LGIPRSRANI ALWPPVREKR VRIYLSKGPN VKNWNAWTAL ETYLQLQEAF
       850        860        870        880        890        900
GWEPFIRLFT EYRNQTNLPT ENVDKMNLWV KMFSHQVQKN LAPFFEAWAW PIQKEVATSL
       910        920
AYLPEWKENI MKLYLLTQMP H         10         20         30         40         50         60
MATPSAAFEA LMNGVTSWDV PEDAVPCELL LIGEASFPVM VNDMGQVLIA ASSYGRGRLV
        70         80         90        100        110        120
VVSHEDYLVE AQLTPFLLNA VGWLCSSPGA PIGVHPSLAP LAKILEGSGV DAKVEPEVKD
       130        140        150        160        170        180
SLGVYCIDAY NETMTEKLVK FMKCGGGLLI GGQAWDWANQ GEDERVLFTF PGNLVTSVAG
       190        200        210        220        230        240
IYFTDNKGDT SFFKVSKKMP KIPVLVSCED DLSDDREELL HGISELDISN SDCFPSQLLV
       250        260        270        280        290        300
HGALAFPLGL DSYHGCVIAA ARYGRGRVVV TGHKVLFTVG KLGPFLLNAV RWLDGGRRGK
       310        320        330        340        350        360
VVVQTELRTL SGLLAVGGID TSIEPNLTSD ASVYCFEPVS EVGVKELQEF VAEGGGLFVG
       370        380        390        400        410        420
AQAWWWAFKN PGVSPLARFP GNLLLNPFGI SITSQSLNPG PFRTPKAGIR TYHFRSTLAE
       430        440        450        460        470        480
FQVIMGRKRG NVEKGWLAKL GPDGAAFLQI PAEEIPAYMS VHRLLRKLLS RYRLPVATRE
       490        500        510        520        530        540
NPVINDCCRG AMLSLATGLA HSGSDLSLLV PEIEDMYSSP YLRPSESPIT VEVNCTNPGT
       550        560        570        580        590        600
RYCWMSTGLY IPGRQIIEVS LPEAAASADL KIQIGCHTDD LTRASKLFRG PLVINRCCLD
       610        620        630        640        650        660
KPTKSITCLW GGLLYIIVPQ NSKLGSVPVT VKGAVHAPYY KLGETTLEEW KRRIQENPGP
       670        680        690        700        710        720
WGELATDNII LTVPTANLRT LENPEPLLRL WDEVMQAVAR LGAEPFPLRL PQRIVADVQI
       730        740        750        760        770        780
SVGWMHAGYP IMCHLESVQE LINEKLIRTK GLWGPVHELG RNQQRQEWEF PPHTTEATCN
       790        800        810        820        830        840
LWCVYVHETV LGIPRSRANI ALWPPVREKR VRIYLSKGPN VKNWNAWTAL ETYLQLQEAF
       850        860        870        880        890        900
GWEPFIRLFT EYRNQTNLPT ENVDKMNLWV KMFSHQVQKN LAPFFEAWAW PIQKEVATSL
       910        920
AYLPEWKENI MKLYLLTQMP H

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9Y4C2-1-unknown	MATPSA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9Y4C2-1-unknown	MATPSA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74386
Q9Y4C2-152-unknown	GQAWDW...	152	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4304
Q9Y4C2-152-unknown	GQAWDW...	152	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt144830

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GLLIGG	151	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4304
...GLLIGG	151	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128106
...LLTQMP	919	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70004
...TQMPH	921	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

TopFIND

Q9Y4C2: TRPM8 channel-associated factor 1 {ECO:0000303|PubMed:25559186}

General Information

2

N-termini

3

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates