Q8WVV9: Heterogeneous nuclear ribonucleoprotein L-like

General Information

Protein names	- Heterogeneous nuclear ribonucleoprotein L-like - hnRNPLL - Stromal RNA-regulating factor
Gene names	HNRNPLL
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8WVV9

6 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Heterogeneous nuclear ribonucleoprotein L-like - Isoform 3 of Heterogeneous nuclear ribonucleoprotein L-like - Isoform 4 of Heterogeneous nuclear ribonucleoprotein L-like - Isoform 5 of Heterogeneous nuclear ribonucleoprotein L-like

Sequence View

        10         20         30         40         50         60
MSSSSSSPRE TYEEDREYES QAKRLKTEEG EIDYSAEEGE NRREATPRGG GDGGGGGRSF
        70         80         90        100        110        120
SQPEAGGSHH KVSVSPVVHV RGLCESVVEA DLVEALEKFG TICYVMMMPF KRQALVEFEN
       130        140        150        160        170        180
IDSAKECVTF AADEPVYIAG QQAFFNYSTS KRITRPGNTD DPSGGNKVLL LSIQNPLYPI
       190        200        210        220        230        240
TVDVLYTVCN PVGKVQRIVI FKRNGIQAMV EFESVLCAQK AKAALNGADI YAGCCTLKIE
       250        260        270        280        290        300
YARPTRLNVI RNDNDSWDYT KPYLGRRDRG KGRQRQAILG EHPSSFRHDG YGSHGPLLPL
       310        320        330        340        350        360
PSRYRMGSRD TPELVAYPLP QASSSYMHGG NPSGSVVMVS GLHQLKMNCS RVFNLFCLYG
       370        380        390        400        410        420
NIEKVKFMKT IPGTALVEMG DEYAVERAVT HLNNVKLFGK RLNVCVSKQH SVVPSQIFEL
       430        440        450        460        470        480
EDGTSSYKDF AMSKNNRFTS AGQASKNIIQ PPSCVLHYYN VPLCVTEETF TKLCNDHEVL
       490        500        510        520        530        540
TFIKYKVFDA KPSAKTLSGL LEWECKTDAV EALTALNHYQ IRVPNGSNPY TLKLCFSTSS

HL         10         20         30         40         50         60
MSSSSSSPRE TYEEDREYES QAKRLKTEEG EIDYSAEEGE NRREATPRGG GDGGGGGRSF
        70         80         90        100        110        120
SQPEAGGSHH KVSVSPVVHV RGLCESVVEA DLVEALEKFG TICYVMMMPF KRQALVEFEN
       130        140        150        160        170        180
IDSAKECVTF AADEPVYIAG QQAFFNYSTS KRITRPGNTD DPSGGNKVLL LSIQNPLYPI
       190        200        210        220        230        240
TVDVLYTVCN PVGKVQRIVI FKRNGIQAMV EFESVLCAQK AKAALNGADI YAGCCTLKIE
       250        260        270        280        290        300
YARPTRLNVI RNDNDSWDYT KPYLGRRDRG KGRQRQAILG EHPSSFRHDG YGSHGPLLPL
       310        320        330        340        350        360
PSRYRMGSRD TPELVAYPLP QASSSYMHGG NPSGSVVMVS GLHQLKMNCS RVFNLFCLYG
       370        380        390        400        410        420
NIEKVKFMKT IPGTALVEMG DEYAVERAVT HLNNVKLFGK RLNVCVSKQH SVVPSQIFEL
       430        440        450        460        470        480
EDGTSSYKDF AMSKNNRFTS AGQASKNIIQ PPSCVLHYYN VPLCVTEETF TKLCNDHEVL
       490        500        510        520        530        540
TFIKYKVFDA KPSAKTLSGL LEWECKTDAV EALTALNHYQ IRVPNGSNPY TLKLCFSTSS

HL         10         20         30         40         50         60
MSSSSSSPRE TYEEDREYES QAKRLKTEEG EIDYSAEEGE NRREATPRGG GDGGGGGRSF
        70         80         90        100        110        120
SQPEAGGSHH KVSVSPVVHV RGLCESVVEA DLVEALEKFG TICYVMMMPF KRQALVEFEN
       130        140        150        160        170        180
IDSAKECVTF AADEPVYIAG QQAFFNYSTS KRITRPGNTD DPSGGNKVLL LSIQNPLYPI
       190        200        210        220        230        240
TVDVLYTVCN PVGKVQRIVI FKRNGIQAMV EFESVLCAQK AKAALNGADI YAGCCTLKIE
       250        260        270        280        290        300
YARPTRLNVI RNDNDSWDYT KPYLGRRDRG KGRQRQAILG EHPSSFRHDG YGSHGPLLPL
       310        320        330        340        350        360
PSRYRMGSRD TPELVAYPLP QASSSYMHGG NPSGSVVMVS GLHQLKMNCS RVFNLFCLYG
       370        380        390        400        410        420
NIEKVKFMKT IPGTALVEMG DEYAVERAVT HLNNVKLFGK RLNVCVSKQH SVVPSQIFEL
       430        440        450        460        470        480
EDGTSSYKDF AMSKNNRFTS AGQASKNIIQ PPSCVLHYYN VPLCVTEETF TKLCNDHEVL
       490        500        510        520        530        540
TFIKYKVFDA KPSAKTLSGL LEWECKTDAV EALTALNHYQ IRVPNGSNPY TLKLCFSTSS

HL         10         20         30         40         50         60
MSSSSSSPRE TYEEDREYES QAKRLKTEEG EIDYSAEEGE NRREATPRGG GDGGGGGRSF
        70         80         90        100        110        120
SQPEAGGSHH KVSVSPVVHV RGLCESVVEA DLVEALEKFG TICYVMMMPF KRQALVEFEN
       130        140        150        160        170        180
IDSAKECVTF AADEPVYIAG QQAFFNYSTS KRITRPGNTD DPSGGNKVLL LSIQNPLYPI
       190        200        210        220        230        240
TVDVLYTVCN PVGKVQRIVI FKRNGIQAMV EFESVLCAQK AKAALNGADI YAGCCTLKIE
       250        260        270        280        290        300
YARPTRLNVI RNDNDSWDYT KPYLGRRDRG KGRQRQAILG EHPSSFRHDG YGSHGPLLPL
       310        320        330        340        350        360
PSRYRMGSRD TPELVAYPLP QASSSYMHGG NPSGSVVMVS GLHQLKMNCS RVFNLFCLYG
       370        380        390        400        410        420
NIEKVKFMKT IPGTALVEMG DEYAVERAVT HLNNVKLFGK RLNVCVSKQH SVVPSQIFEL
       430        440        450        460        470        480
EDGTSSYKDF AMSKNNRFTS AGQASKNIIQ PPSCVLHYYN VPLCVTEETF TKLCNDHEVL
       490        500        510        520        530        540
TFIKYKVFDA KPSAKTLSGL LEWECKTDAV EALTALNHYQ IRVPNGSNPY TLKLCFSTSS

HL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8WVV9-1-unknown	MSSSSS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8WVV9-1-unknown	MSSSSS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt77155
Q8WVV9-1-unknown	MSSSSS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt77158
Q8WVV9-61-	SQPEAG...	61		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q8WVV9-61-unknown	SQPEAG...	61	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178508
Q8WVV9-61-unknown	SQPEAG...	61	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178509
Q8WVV9-61-unknown	SQPEAG...	61	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178507
Q8WVV9-61-unknown	SQPEAG...	61	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178510
Q8WVV9-290-unknown	GYGSHG...	290	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1331
Q8WVV9-290-unknown	GYGSHG...	290	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148676
Q8WVV9-290-unknown	GYGSHG...	290	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149461
Q8WVV9-290-	GYGSHG...	290		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q8WVV9-293-unknown	SHGPLL...	293	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4158
Q8WVV9-293-unknown	SHGPLL...	293	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148768
Q8WVV9-293-unknown	SHGPLL...	293	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149545

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IQAMVE	210	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000396669
...IQAMVE	210	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt111938
...IQAMVE	210	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt111939
...IQAMVE	210	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt111937
...IQAMVE	210	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt111940
...SFRHDG	289	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1331
...SFRHDG	289	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132051
...SFRHDG	289	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132846
...HDGYGS	292	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4158
...HDGYGS	292	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132144
...HDGYGS	292	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132929
...TSSHL	542	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TSSHL	542	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72776
...TSSHL	542	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72775

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP1_HUMAN	289	RHDG.\|.GYGS	inferred from experiment	unknown	MEROPS	Wells JA	Agard NJ et al.:Inflammatory stimuli regulate c... (C14.001)	20173201,
CATB_HUMAN	292	GYGS.\|.SHGP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)