P46778: 60S ribosomal protein L21

General Information

Protein names	- 60S ribosomal protein L21 - Large ribosomal subunit protein eL21 {ECO:0000303\|PubMed:24524803}
Gene names	RPL21
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P46778

9 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTNTKGKRRG TRYMFSRPFR KHGVVPLATY MRIYKKGDIV DIKGMGTVQK GMPHKCYHGK
        70         80         90        100        110        120
TGRVYNVTQH AVGIVVNKQV KGKILAKRIN VRIEHIKHSK SRDSFLKRVK ENDQKKKEAK
       130        140        150        160
EKGTWVQLKR QPAPPREAHF VRTNGKEPEL LEPIPYEFMA

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

9 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P46778-1-unknown	MTNTKG...	1		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P46778-1-unknown	MTNTKG...	1		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P46778-1-	MTNTKG...	1		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P46778-2-unknown	TNTKGK...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P46778-2-unknown	TNTKGK...	2		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P46778-2-unknown	TNTKGK...	2		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P46778-21-	KHGVVP...	21		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P46778-21-unknown	KHGVVP...	21		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P46778-44-	GMGTVQ...	44		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P46778-64-	VYNVTQ...	64		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P46778-71-	AVGIVV...	71		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P46778-71-unknown	AVGIVV...	71	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3806

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...NVTQHA	70	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3806
...EAKEKG	122	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000471695
...YEFMA	160	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...YEFMA	160		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...YEFMA	160		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	70	TQHA.\|.AVGI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)