P35606: Coatomer subunit beta'

General Information

Protein names	- Coatomer subunit beta' - Beta'-coat protein - Beta'-COP - p102
Gene names	COPB2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P35606

6 N-termini

8 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPLRLDIKRK LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV
        70         80         90        100        110        120
RAAKFVARKN WVVTGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPFILTSSDD
       130        140        150        160        170        180
MLIKLWDWDK KWSCSQVFEG HTHYVMQIVI NPKDNNQFAS ASLDRTIKVW QLGSSSPNFT
       190        200        210        220        230        240
LEGHEKGVNC IDYYSGGDKP YLISGADDRL VKIWDYQNKT CVQTLEGHAQ NVSCASFHPE
       250        260        270        280        290        300
LPIIITGSED GTVRIWHSST YRLESTLNYG MERVWCVASL RGSNNVALGY DEGSIIVKLG
       310        320        330        340        350        360
REEPAMSMDA NGKIIWAKHS EVQQANLKAM GDAEIKDGER LPLAVKDMGS CEIYPQTIQH
       370        380        390        400        410        420
NPNGRFVVVC GDGEYIIYTA MALRNKSFGS AQEFAWAHDS SEYAIRESNS IVKIFKNFKE
       430        440        450        460        470        480
KKSFKPDFGA ESIYGGFLLG VRSVNGLAFY DWDNTELIRR IEIQPKHIFW SDSGELVCIA
       490        500        510        520        530        540
TEESFFILKY LSEKVLAAQE THEGVTEDGI EDAFEVLGEI QEIVKTGLWV GDCFIYTSSV
       550        560        570        580        590        600
NRLNYYVGGE IVTIAHLDRT MYLLGYIPKD NRLYLGDKEL NIISYSLLVS VLEYQTAVMR
       610        620        630        640        650        660
RDFSMADKVL PTIPKEQRTR VAHFLEKQGF KQQALTVSTD PEHRFELALQ LGELKIAYQL
       670        680        690        700        710        720
AVEAESEQKW KQLAELAISK CQFGLAQECL HHAQDYGGLL LLATASGNAN MVNKLAEGAE
       730        740        750        760        770        780
RDGKNNVAFM SYFLQGKVDA CLELLIRTGR LPEAAFLART YLPSQVSRVV KLWRENLSKV
       790        800        810        820        830        840
NQKAAESLAD PTEYENLFPG LKEAFVVEEW VKETHADLWP AKQYPLVTPN EERNVMEEGK
       850        860        870        880        890        900
DFQPSRSTAQ QELDGKPASP TPVIVASHTA NKEEKSLLEL EVDLDNLELE DIDTTDINLD

EDILDD

Isoforms

- Isoform 2 of Coatomer subunit beta'

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 8 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P35606-2-unknown	PLRLDI...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P35606-30-unknown	MLASLY...	30	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000422295
P35606-30-unknown	MLASLY...	30	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000422547
P35606-30-unknown	MLASLY...	30	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000424144
P35606-30-unknown	MLASLY...	30	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000427185
P35606-30-unknown	MLASLY...	30	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000422469
P35606-172-unknown	LGSSSP...	172	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3780
P35606-288-unknown	LGYDEG...	288	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5817
P35606-378-unknown	YTAMAL...	378	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000422917
P35606-855-	GKPASP...	855		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IRCIAV	106	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000422469
...QPFILT	115	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000427185
...ILTSSD	118	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000424144
...QVFEGH	140	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000422547
...IKVWQL	171	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3780
...VWQLGS	173	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000423271
...SNNVAL	287	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5817
...DILDD	906	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	171	VWQL.\|.LGSS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	287	NVAL.\|.LGYD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)