Q13310: Polyadenylate-binding protein 4
Protein names | - Polyadenylate-binding protein 4 - PABP-4 - Poly(A)-binding protein 4 - Activated-platelet protein 1 - APP-1 - Inducible poly(A)-binding protein - iPABP |
---|---|
Gene names | PABPC4 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q13310 |
8
N-termini
6
C-termini
5
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MNAAASSYPM ASLYVGDLHS DVTEAMLYEK FSPAGPVLSI RVCRDMITRR SLGYAYVNFQ
70 80 90 100 110 120
QPADAERALD TMNFDVIKGK PIRIMWSQRD PSLRKSGVGN VFIKNLDKSI DNKALYDTFS
130 140 150 160 170 180
AFGNILSCKV VCDENGSKGY AFVHFETQEA ADKAIEKMNG MLLNDRKVFV GRFKSRKERE
190 200 210 220 230 240
AELGAKAKEF TNVYIKNFGE EVDDESLKEL FSQFGKTLSV KVMRDPNGKS KGFGFVSYEK
250 260 270 280 290 300
HEDANKAVEE MNGKEISGKI IFVGRAQKKV ERQAELKRKF EQLKQERISR YQGVNLYIKN
310 320 330 340 350 360
LDDTIDDEKL RKEFSPFGSI TSAKVMLEDG RSKGFGFVCF SSPEEATKAV TEMNGRIVGS
370 380 390 400 410 420
KPLYVALAQR KEERKAHLTN QYMQRVAGMR ALPANAILNQ FQPAAGGYFV PAVPQAQGRP
430 440 450 460 470 480
PYYTPNQLAQ MRPNPRWQQG GRPQGFQGMP SAIRQSGPRP TLRHLAPTGS ECPDRLAMDF
490 500 510 520 530 540
GGAGAAQQGL TDSCQSGGVP TAVQNLAPRA AVAAAAPRAV APYKYASSVR SPHPAIQPLQ
550 560 570 580 590 600
APQPAVHVQG QEPLTASMLA AAPPQEQKQM LGERLFPLIQ TMHSNLAGKI TGMLLEIDNS
610 620 630 640
ELLHMLESPE SLRSKVDEAV AVLQAHHAKK EAAQKVGAVA AATS
Isoforms
- Isoform 2 of Polyadenylate-binding protein 4 - Isoform 3 of Polyadenylate-binding protein 4Sequence View
10 20 30 40 50 60
MNAAASSYPM ASLYVGDLHS DVTEAMLYEK FSPAGPVLSI RVCRDMITRR SLGYAYVNFQ
70 80 90 100 110 120
QPADAERALD TMNFDVIKGK PIRIMWSQRD PSLRKSGVGN VFIKNLDKSI DNKALYDTFS
130 140 150 160 170 180
AFGNILSCKV VCDENGSKGY AFVHFETQEA ADKAIEKMNG MLLNDRKVFV GRFKSRKERE
190 200 210 220 230 240
AELGAKAKEF TNVYIKNFGE EVDDESLKEL FSQFGKTLSV KVMRDPNGKS KGFGFVSYEK
250 260 270 280 290 300
HEDANKAVEE MNGKEISGKI IFVGRAQKKV ERQAELKRKF EQLKQERISR YQGVNLYIKN
310 320 330 340 350 360
LDDTIDDEKL RKEFSPFGSI TSAKVMLEDG RSKGFGFVCF SSPEEATKAV TEMNGRIVGS
370 380 390 400 410 420
KPLYVALAQR KEERKAHLTN QYMQRVAGMR ALPANAILNQ FQPAAGGYFV PAVPQAQGRP
430 440 450 460 470 480
PYYTPNQLAQ MRPNPRWQQG GRPQGFQGMP SAIRQSGPRP TLRHLAPTGS ECPDRLAMDF
490 500 510 520 530 540
GGAGAAQQGL TDSCQSGGVP TAVQNLAPRA AVAAAAPRAV APYKYASSVR SPHPAIQPLQ
550 560 570 580 590 600
APQPAVHVQG QEPLTASMLA AAPPQEQKQM LGERLFPLIQ TMHSNLAGKI TGMLLEIDNS
610 620 630 640
ELLHMLESPE SLRSKVDEAV AVLQAHHAKK EAAQKVGAVA AATS
10 20 30 40 50 60
MNAAASSYPM ASLYVGDLHS DVTEAMLYEK FSPAGPVLSI RVCRDMITRR SLGYAYVNFQ
70 80 90 100 110 120
QPADAERALD TMNFDVIKGK PIRIMWSQRD PSLRKSGVGN VFIKNLDKSI DNKALYDTFS
130 140 150 160 170 180
AFGNILSCKV VCDENGSKGY AFVHFETQEA ADKAIEKMNG MLLNDRKVFV GRFKSRKERE
190 200 210 220 230 240
AELGAKAKEF TNVYIKNFGE EVDDESLKEL FSQFGKTLSV KVMRDPNGKS KGFGFVSYEK
250 260 270 280 290 300
HEDANKAVEE MNGKEISGKI IFVGRAQKKV ERQAELKRKF EQLKQERISR YQGVNLYIKN
310 320 330 340 350 360
LDDTIDDEKL RKEFSPFGSI TSAKVMLEDG RSKGFGFVCF SSPEEATKAV TEMNGRIVGS
370 380 390 400 410 420
KPLYVALAQR KEERKAHLTN QYMQRVAGMR ALPANAILNQ FQPAAGGYFV PAVPQAQGRP
430 440 450 460 470 480
PYYTPNQLAQ MRPNPRWQQG GRPQGFQGMP SAIRQSGPRP TLRHLAPTGS ECPDRLAMDF
490 500 510 520 530 540
GGAGAAQQGL TDSCQSGGVP TAVQNLAPRA AVAAAAPRAV APYKYASSVR SPHPAIQPLQ
550 560 570 580 590 600
APQPAVHVQG QEPLTASMLA AAPPQEQKQM LGERLFPLIQ TMHSNLAGKI TGMLLEIDNS
610 620 630 640
ELLHMLESPE SLRSKVDEAV AVLQAHHAKK EAAQKVGAVA AATS
Protein Neighborhood
Domains & Features
8 N-termini - 6 C-termini - 5 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q13310-1-unknown | MNAAAS... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q13310-1-unknown | MNAAAS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt84136 | |||
Q13310-1-unknown | MNAAAS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt84137 | |||
Q13310-14- | YVGDLH... | 14 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q13310-14-unknown | YVGDLH... | 14 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174474 | |||
Q13310-14-unknown | YVGDLH... | 14 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt174475 | |||
Q13310-142-unknown | FVHFET... | 142 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3986 | |||
Q13310-142-unknown | FVHFET... | 142 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144412 | |||
Q13310-142-unknown | FVHFET... | 142 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144413 | |||
Q13310-480-unknown | FGGAGA... | 480 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12019 | |||
Q13310-480-unknown | FGGAGA... | 480 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153375 | |||
Q13310-491-unknown | TDSCQS... | 491 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14406 | |||
Q13310-491-unknown | TDSCQS... | 491 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153498 | |||
Q13310-540-unknown | QAPQPA... | 540 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14408 | |||
Q13310-540-unknown | QAPQPA... | 540 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153714 | |||
Q13310-540-unknown | QAPQPA... | 540 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt154049 | |||
Q13310-618-unknown | EAVAVL... | 618 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19421 | |||
Q13310-618-unknown | EAVAVL... | 618 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt154652 | |||
Q13310-618-unknown | EAVAVL... | 618 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt155125 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...SKGYAF | 141 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3986 | |||
...SKGYAF | 141 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt127676 | |||
...SKGYAF | 141 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt127677 | |||
...RLAMDF | 479 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12019 | |||
...AQQGLT | 490 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14406 | |||
...AQQGLT | 490 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136921 | |||
...AIQPLQ | 539 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14408 | |||
...AIQPLQ | 539 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt137137 | |||
...AIQPLQ | 539 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt137468 | |||
...RSKVDE | 617 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19421 | |||
...RSKVDE | 617 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt138077 | |||
...RSKVDE | 617 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt138552 | |||
...AAATS | 644 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...AAATS | 644 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt79754 | |||
...AAATS | 644 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt79755 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATB_HUMAN | 141 | GYAF.|.FVHF | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
GRAB_HUMAN | 479 | AMDF.|.FGGA | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
GRAM_HUMAN | 490 | QGLT.|.TDSC | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
GRAM_HUMAN | 539 | QPLQ.|.QAPQ | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
MEP1B_HUMAN | 617 | KVDE.|.EAVA | inferred from experiment | unknown | MEROPS | Overall CM | Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) | 21693781, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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