TopFIND 4.0

P58546: Myotrophin

General Information

Protein names	- Myotrophin - Protein V-1
Gene names	MTPN
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P58546

4

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MCDKEFMWAL KNGDLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD
70 80 90 100 110
INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPD GLTAFEATDN QAIKALLQ

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P58546-2-unknown	MCDKEF...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P58546-2-Acetylation	CDKEFM...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P58546-2-Acetylation	CDKEFM...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P58546-2-Acetylation	CDKEFM...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P58546-13-	GDLDEV...	13			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P58546-102-unknown	LTAFEA...	102		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3873

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...KGPDGL	101	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3873
	...KALLQ	118	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	101	PDGL.\|.LTAF	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)