Q9GZU1: Mucolipin-1 {ECO:0000303|PubMed:12459486}
Protein names | - Mucolipin-1 {ECO:0000303|PubMed:12459486} - ML1 - MG-2 - Mucolipidin {ECO:0000303|PubMed:11013137} - Transient receptor potential channel mucolipin 1 - TRPML1 {ECO:0000303|PubMed:28112729} |
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Gene names | MCOLN1 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9GZU1 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MTAPAGPRGS ETERLLTPNP GYGTQAGPSP APPTPPEEED LRRRLKYFFM SPCDKFRAKG
70 80 90 100 110 120
RKPCKLMLQV VKILVVTVQL ILFGLSNQLA VTFREENTIA FRHLFLLGYS DGADDTFAAY
130 140 150 160 170 180
TREQLYQAIF HAVDQYLALP DVSLGRYAYV RGGGDPWTNG SGLALCQRYY HRGHVDPAND
190 200 210 220 230 240
TFDIDPMVVT DCIQVDPPER PPPPPSDDLT LLESSSSYKN LTLKFHKLVN VTIHFRLKTI
250 260 270 280 290 300
NLQSLINNEI PDCYTFSVLI TFDNKAHSGR IPISLETQAH IQECKHPSVF QHGDNSFRLL
310 320 330 340 350 360
FDVVVILTCS LSFLLCARSL LRGFLLQNEF VGFMWRQRGR VISLWERLEF VNGWYILLVT
370 380 390 400 410 420
SDVLTISGTI MKIGIEAKNL ASYDVCSILL GTSTLLVWVG VIRYLTFFHN YNILIATLRV
430 440 450 460 470 480
ALPSVMRFCC CVAVIYLGYC FCGWIVLGPY HVKFRSLSMV SECLFSLING DDMFVTFAAM
490 500 510 520 530 540
QAQQGRSSLV WLFSQLYLYS FISLFIYMVL SLFIALITGA YDTIKHPGGA GAEESELQAY
550 560 570 580
IAQCQDSPTS GKFRRGSGSA CSLLCCCGRD PSEEHSLLVN
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9GZU1-1-unknown | MTAPAG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9GZU1-201-unknown | PPPPPS... | 201 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4246 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...DPPERP | 200 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4246 | |||
...SLLVN | 580 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATB_HUMAN | 200 | PERP.|.PPPP | inferred from experiment | unknown | MEROPS | Soyombo A | Kiselyov K et al.:TRP-ML1 is a lysosomal monovale... (C01.060) | 16257972, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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