Q15631: Translin

General Information

Protein names	- Translin - 3.1.-.- - Component 3 of promoter of RISC - C3PO
Gene names	TSN
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15631

5 N-termini

5 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSVSEIFVEL QGFLAAEQDI REEIRKVVQS LEQTAREILT LLQGVHQGAG FQDIPKRCLK
        70         80         90        100        110        120
AREHFGTVKT HLTSLKTKFP AEQYYRFHEH WRFVLQRLVF LAAFVVYLET ETLVTREAVT
       130        140        150        160        170        180
EILGIEPDRE KGFHLDVEDY LSGVLILASE LSRLSVNSVT AGDYSRPLHI STFINELDSG
       190        200        210        220
FRLLNLKNDS LRKRYDGLKY DVKKVEEVVY DLSIRGFNKE TAAACVEK

Isoforms

- Isoform 2 of Translin

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q15631-1-unknown	MSVSEI...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q15631-1-unknown	MSVSEI...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93295
Q15631-13-unknown	FLAAEQ...	13	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4100
Q15631-13-unknown	FLAAEQ...	13	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136393
Q15631-42-unknown	LQGVHQ...	42	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4102
Q15631-42-unknown	LQGVHQ...	42	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138479
Q15631-44-unknown	GVHQGA...	44	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4104
Q15631-44-unknown	GVHQGA...	44	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138627
Q15631-158-	SVTAGD...	158		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q15631-158-	SVTAGD...	158		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...VELQGF	12	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4100
...EILTLL	41	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4102
...EILTLL	41	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt121523
...LTLLQG	43	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4104
...LTLLQG	43	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt121680
...ACVEK	228		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...ACVEK	228	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...ACVEK	228		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...ACVEK	228		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	12	LQGF.\|.FLAA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	41	LTLL.\|.LQGV	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	43	LLQG.\|.GVHQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)