TopFIND 4.0

Q14CN2: Calcium-activated chloride channel regulator 4

General Information

Protein names
- Calcium-activated chloride channel regulator 4
- 3.4.-.- {ECO:0000250|UniProtKB:A8K7I4}
- Calcium-activated chloride channel family member 4
- hCLCA4
- Calcium-activated chloride channel protein 2
- CaCC-2
- hCaCC-2
- Chloride channel accessory 4
- Calcium-activated chloride channel regulator 4, 110 kDa form
- Calcium-activated chloride channel regulator 4, 30 kDa form
Gene names CLCA4
Organism Homo sapiens
Protease Family M87.002
Protease ID M87.002
Chromosome location
UniProt ID Q14CN2

5

N-termini

4

C-termini

2

Cleavages

1

Substrates

Sequence

        10         20         30         40         50         60 
MGLFRGFVFL LVLCLLHQSN TSFIKLNNNG FEDIVIVIDP SVPEDEKIIE QIEDMVTTAS 
        70         80         90        100        110        120 
TYLFEATEKR FFFKNVSILI PENWKENPQY KRPKHENHKH ADVIVAPPTL PGRDEPYTKQ 
       130        140        150        160        170        180 
FTECGEKGEY IHFTPDLLLG KKQNEYGPPG KLFVHEWAHL RWGVFDEYNE DQPFYRAKSK 
       190        200        210        220        230        240 
KIEATRCSAG ISGRNRVYKC QGGSCLSRAC RIDSTTKLYG KDCQFFPDKV QTEKASIMFM 
       250        260        270        280        290        300 
QSIDSVVEFC NEKTHNQEAP SLQNIKCNFR STWEVISNSE DFKNTIPMVT PPPPPVFSLL 
       310        320        330        340        350        360 
KISQRIVCLV LDKSGSMGGK DRLNRMNQAA KHFLLQTVEN GSWVGMVHFD STATIVNKLI 
       370        380        390        400        410        420 
QIKSSDERNT LMAGLPTYPL GGTSICSGIK YAFQVIGELH SQLDGSEVLL LTDGEDNTAS 
       430        440        450        460        470        480 
SCIDEVKQSG AIVHFIALGR AADEAVIEMS KITGGSHFYV SDEAQNNGLI DAFGALTSGN 
       490        500        510        520        530        540 
TDLSQKSLQL ESKGLTLNSN AWMNDTVIID STVGKDTFFL ITWNSLPPSI SLWDPSGTIM 
       550        560        570        580        590        600 
ENFTVDATSK MAYLSIPGTA KVGTWAYNLQ AKANPETLTI TVTSRAANSS VPPITVNAKM 
       610        620        630        640        650        660 
NKDVNSFPSP MIVYAEILQG YVPVLGANVT AFIESQNGHT EVLELLDNGA GADSFKNDGV 
       670        680        690        700        710        720 
YSRYFTAYTE NGRYSLKVRA HGGANTARLK LRPPLNRAAY IPGWVVNGEI EANPPRPEID 
       730        740        750        760        770        780 
EDTQTTLEDF SRTASGGAFV VSQVPSLPLP DQYPPSQITD LDATVHEDKI ILTWTAPGDN 
       790        800        810        820        830        840 
FDVGKVQRYI IRISASILDL RDSFDDALQV NTTDLSPKEA NSKESFAFKP ENISEENATH 
       850        860        870        880        890        900 
IFIAIKSIDK SNLTSKVSNI AQVTLFIPQA NPDDIDPTPT PTPTPTPDKS HNSGVNISTL 
       910    
VLSVIGSVVI VNFILSTTI

Isoforms

- Isoform 2 of Calcium-activated chloride channel regulator 4

Sequence View

        10         20         30         40         50         60 
MGLFRGFVFL LVLCLLHQSN TSFIKLNNNG FEDIVIVIDP SVPEDEKIIE QIEDMVTTAS 
        70         80         90        100        110        120 
TYLFEATEKR FFFKNVSILI PENWKENPQY KRPKHENHKH ADVIVAPPTL PGRDEPYTKQ 
       130        140        150        160        170        180 
FTECGEKGEY IHFTPDLLLG KKQNEYGPPG KLFVHEWAHL RWGVFDEYNE DQPFYRAKSK 
       190        200        210        220        230        240 
KIEATRCSAG ISGRNRVYKC QGGSCLSRAC RIDSTTKLYG KDCQFFPDKV QTEKASIMFM 
       250        260        270        280        290        300 
QSIDSVVEFC NEKTHNQEAP SLQNIKCNFR STWEVISNSE DFKNTIPMVT PPPPPVFSLL 
       310        320        330        340        350        360 
KISQRIVCLV LDKSGSMGGK DRLNRMNQAA KHFLLQTVEN GSWVGMVHFD STATIVNKLI 
       370        380        390        400        410        420 
QIKSSDERNT LMAGLPTYPL GGTSICSGIK YAFQVIGELH SQLDGSEVLL LTDGEDNTAS 
       430        440        450        460        470        480 
SCIDEVKQSG AIVHFIALGR AADEAVIEMS KITGGSHFYV SDEAQNNGLI DAFGALTSGN 
       490        500        510        520        530        540 
TDLSQKSLQL ESKGLTLNSN AWMNDTVIID STVGKDTFFL ITWNSLPPSI SLWDPSGTIM 
       550        560        570        580        590        600 
ENFTVDATSK MAYLSIPGTA KVGTWAYNLQ AKANPETLTI TVTSRAANSS VPPITVNAKM 
       610        620        630        640        650        660 
NKDVNSFPSP MIVYAEILQG YVPVLGANVT AFIESQNGHT EVLELLDNGA GADSFKNDGV 
       670        680        690        700        710        720 
YSRYFTAYTE NGRYSLKVRA HGGANTARLK LRPPLNRAAY IPGWVVNGEI EANPPRPEID 
       730        740        750        760        770        780 
EDTQTTLEDF SRTASGGAFV VSQVPSLPLP DQYPPSQITD LDATVHEDKI ILTWTAPGDN 
       790        800        810        820        830        840 
FDVGKVQRYI IRISASILDL RDSFDDALQV NTTDLSPKEA NSKESFAFKP ENISEENATH 
       850        860        870        880        890        900 
IFIAIKSIDK SNLTSKVSNI AQVTLFIPQA NPDDIDPTPT PTPTPTPDKS HNSGVNISTL 
       910    
VLSVIGSVVI VNFILSTTI



Filter Information:


(REFRESH)

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 2 Cleavages - 1 Substrates

N-termini

C-termini

Cleavages

Substrates