Q92733: Proline-rich protein PRCC

General Information

Protein names	- Proline-rich protein PRCC - Papillary renal cell carcinoma translocation-associated gene protein
Gene names	PRCC
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q92733

5 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSLVAYASSD ESEPDEAEPE PEEEEAVAPT SGPALGGLFA SLPAPKGPAL LPPPPQMLAP
        70         80         90        100        110        120
AFPPPLLLPP PTGDPRLQPP PPLPFGLGGF PPPPGVSPAE AAGVGEGLGL GLPSPRGPGL
       130        140        150        160        170        180
NLPPPIGGAG PPLGLPKPKK RKEPVKIAAP ELHKGDSDSE EDEPTKKKTI LQGSSEGTGL
       190        200        210        220        230        240
SALLPQPKNL TVKETNRLLL PHAFSRKPSD GSPDTKPSRL ASKTKTSSLA PVVGTTTTTP
       250        260        270        280        290        300
SPSAIKAAAK SAALQVTKQI TQEEDDSDEE VAPENFFSLP EKAEPPGVEP YPYPIPTVPE
       310        320        330        340        350        360
ELPPGTEPEP AFQDDAANAP LEFKMAAGSS GAPWMPKPGD DYSYNQFSTY GDANAAGAYY
       370        380        390        400        410        420
QDYYSGGYYP AQDPALVPPQ EIAPDASFID DEAFKRLQGK RNRGREEINF VEIKGDDQLS
       430        440        450        460        470        480
GAQQWMTKSL TEEKTMKSFS KKKGEQPTGQ QRRKHQITYL IHQAKERELE LKNTWSENKL
       490
SRRQTQAKYG F

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q92733-1-unknown	MSLVAY...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q92733-37-	GLFASL...	37		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q92733-128-unknown	GAGPPL...	128	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4171
Q92733-262-unknown	QEEDDS...	262	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000434762
Q92733-386-unknown	ASFIDD...	386	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13004

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PPPIGG	127	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4171
...EIAPDA	385	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13004
...AKYGF	491	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	127	PIGG.\|.GAGP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	385	APDA.\|.ASFI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)