P78556: C-C motif chemokine 20

General Information

Protein names	- C-C motif chemokine 20 - Beta-chemokine exodus-1 - CC chemokine LARC - Liver and activation-regulated chemokine - Macrophage inflammatory protein 3 alpha - MIP-3-alpha - Small-inducible cytokine A20 - CCL20(1-67) - CCL20(1-64) - CCL20(2-70)
Gene names	CCL20
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P78556

8 N-termini

9 C-termini

6 Cleavages

0 Substrates

Sequence

10 20 30 40 50 60
MCCTKSLLLA ALMSVLLLHL CGESEAASNF DCCLGYTDRI LHPKFIVGFT RQLANEGCDI
70 80 90
NAIIFHTKKK LSVCANPKQT WVKYIVRLLS KKVKNM

Isoforms

- Isoform 2 of C-C motif chemokine 20

Sequence View

10 20 30 40 50 60
MCCTKSLLLA ALMSVLLLHL CGESEAASNF DCCLGYTDRI LHPKFIVGFT RQLANEGCDI
70 80 90
NAIIFHTKKK LSVCANPKQT WVKYIVRLLS KKVKNM

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

8 N-termini - 9 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P78556-1-unknown	MCCTKS...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt69748
P78556-27-unknown	ASNFDC...	27	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P78556-27-unknown	ASNFDC...	27	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114316
P78556-28-unknown	SNFDCC...	28	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P78556-28-unknown	SNFDCC...	28	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114455
P78556-46-unknown	IVGFTR...	46	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4615
P78556-46-unknown	IVGFTR...	46	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt138700
P78556-49-unknown	FTRQLA...	49	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4617
P78556-49-unknown	FTRQLA...	49	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt138942
P78556-79-unknown	QTWVKY...	79	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4619
P78556-79-unknown	QTWVKY...	79	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141163
P78556-82-unknown	VKYIVR...	82	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4621
P78556-82-unknown	VKYIVR...	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141331
P78556-85-unknown	IVRLLS...	85	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4623
P78556-85-unknown	IVRLLS...	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141501

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LHPKFI	45	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4615
...KFIVGF	48	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4617
...KFIVGF	48	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122009
...CANPKQ	78	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4619
...CANPKQ	78	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124320
...PKQTWV	81	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4621
...PKQTWV	81	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124497
...TWVKYI	84	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4623
...TWVKYI	84	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124678
...VRLLSK	90	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...VRLLSK	90	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91471
...LLSKKV	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3933
...LLSKKV	92	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125113
...LSKKVK	93	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LSKKVK	93	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91481
...KVKNM	96	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KVKNM	96	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65366

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_HUMAN	45	PKFI.\|.IVGF	inferred from experiment	unknown	MEROPS	Wolf M	Hasan L et al.:Function of liver activation-re... (C01.060)	16709808,
CATD_HUMAN	48	IVGF.\|.FTRQ	inferred from experiment	unknown	MEROPS	Wolf M	Hasan L et al.:Function of liver activation-re... (C01.060)	16709808,
CATD_HUMAN	78	NPKQ.\|.QTWV	inferred from experiment	unknown	MEROPS	Wolf M	Hasan L et al.:Function of liver activation-re... (C01.060)	16709808,
CATD_HUMAN	81	QTWV.\|.VKYI	inferred from experiment	unknown	MEROPS	Wolf M	Hasan L et al.:Function of liver activation-re... (C01.060)	16709808,
CATD_HUMAN	84	VKYI.\|.IVRL	inferred from experiment	unknown	MEROPS	Wolf M	Hasan L et al.:Function of liver activation-re... (C01.060)	16709808,
CATB_HUMAN	92	SKKV.\|.VKNM	inferred from experiment	unknown	MEROPS	Wolf M	Hasan L et al.:Function of liver activation-re... (C01.060)	16709808,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)