Q9BVV6: Protein TALPID3
Protein names | - Protein TALPID3 |
---|---|
Gene names | KIAA0586 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9BVV6 |
7
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MPVKRLREVV SQNHGDHLVL LKDELPCVPP ALSANKRLPV GTGTSLNGTS RGSSDLTSAR
70 80 90 100 110 120
NCYQPLLENP MVSESDFSKD VAVQVLPLDK IEENNKQKAN DIFISQYTMG QKDALRTVLK
130 140 150 160 170 180
QKAQSMPVFK EVKVHLLEDA GIEKDAVTQE TRISPSGIDS ATTVAAATAA AIATAAPLIK
190 200 210 220 230 240
VQSDLEAKVN SVTELLSKLQ ETDKHLQRVT EQQTSIQRKQ EKLHCHDHEK QMNVFMEQHI
250 260 270 280 290 300
RHLEKLQQQQ IDIQTHFISA ALKTSSFQPV SMPSSRAVEK YSVKPEHPNL GSCNPSLYNT
310 320 330 340 350 360
FASKQAPLKE VEDTSFDKQK SPLETPAPRR FAPVPVSRDD ELSKRENLLE EKENMEVSCH
370 380 390 400 410 420
RGNVRLLEQI LNNNDSLTRK SESSNTTSLT RSKIGWTPEK TNRFPSCEEL ETTKVTMQKS
430 440 450 460 470 480
DDVLHDLGQK EKETNSMVQP KESLSMLKLP DLPQNSVKLQ TTNTTRSVLK DAEKILRGVQ
490 500 510 520 530 540
NNKKVLEENL EAIIRAKDGA AMYSLINALS TNREMSEKIR IRKTVDEWIK TISAEIQDEL
550 560 570 580 590 600
SRTDYEQKRF DQKNQRTKKG QNMTKDIRTN TQDKTVNKSV IPRKHSQKQI EEHFRNLPMR
610 620 630 640 650 660
GMPASSLQKE RKEGLLKATT VIQDEDYMLQ VYGKPVYQGH RSTLKKGPYL RFNSPSPKSR
670 680 690 700 710 720
PQRPKVIERV KGTKVKSIRT QTDFYATKPK KMDSKMKHSV PVLPHGDQQY LFSPSREMPT
730 740 750 760 770 780
FSGTLEGHLI PMAILLGQTQ SNSDTMPPAG VIVSKPHPVT VTTSIPPSSR KVETGVKKPN
790 800 810 820 830 840
IAIVEMKSEK KDPPQLTVQV LPSVDIDSIS NSSADVLSPL SSPKEASLPP VQTWIKTPEI
850 860 870 880 890 900
MKVDEEEVKF PGTNFDEIID VIQEEEKCDE IPDSEPILEF NRSVKADSTK YNGPPFPPVA
910 920 930 940 950 960
STFQPTADIL DKVIERKETL ENSLIQWVEQ EIMSRIISGL FPVQQQIAPS ISVSVSETSE
970 980 990 1000 1010 1020
PLTSDIVEGT SSGALQLFVD AGVPVNSNVI KHFVNEALAE TIAVMLGDRE AKKQGPVATG
1030 1040 1050 1060 1070 1080
VSGDASTNET YLPARVCTPL PTPQPTPPCS PSSPAKECVL VKTPDSSPCD SDHDMAFPVK
1090 1100 1110 1120 1130 1140
EICAEKGDDM PAIMLVNTPT VTPTTTPPPA AAVFTPTLSD ISIDKLKVSS PELPKPWGDG
1150 1160 1170 1180 1190 1200
DLPLEEENPN SPQEELHPRA IVMSVAKDEE PESMDFPAQP PPPEPVPFMP FPAGTKAPSP
1210 1220 1230 1240 1250 1260
SQMPGSDSST LESTLSVTVT ETETLDKPIS EGEILFSCGQ KLAPKILEDI GLYLTNLNDS
1270 1280 1290 1300 1310 1320
LSSTLHDAVE MEDDPPSEGQ VIRMSHKKFH ADAILSFAKQ NQESAVSQQA VYHSEDLENS
1330 1340 1350 1360 1370 1380
VGELSEGQRP QLTAAAENIL MGHSLYMQPP VTNTQSLDQQ CDPKPLSRQF DTVSGSIYED
1390 1400 1410 1420 1430 1440
SCASHGPMSL GELELEPNSK LVLPTTLLTA QENDVNLPVA AEDFSQYQLK QNQDVKQVEH
1450 1460 1470 1480 1490 1500
KPSQSYLRVR NKSDIAPSQQ QVSPGDMDRT QIELNPYLTC VFSGGKAVPL SASQMPPAKM
1510 1520 1530
SVMLPSVNLE DCSQSLSLST MQEDMESSGA DTF
Isoforms
- Isoform 2 of Protein TALPID3 - Isoform 3 of Protein TALPID3 - Isoform 4 of Protein TALPID3Sequence View
10 20 30 40 50 60
MPVKRLREVV SQNHGDHLVL LKDELPCVPP ALSANKRLPV GTGTSLNGTS RGSSDLTSAR
70 80 90 100 110 120
NCYQPLLENP MVSESDFSKD VAVQVLPLDK IEENNKQKAN DIFISQYTMG QKDALRTVLK
130 140 150 160 170 180
QKAQSMPVFK EVKVHLLEDA GIEKDAVTQE TRISPSGIDS ATTVAAATAA AIATAAPLIK
190 200 210 220 230 240
VQSDLEAKVN SVTELLSKLQ ETDKHLQRVT EQQTSIQRKQ EKLHCHDHEK QMNVFMEQHI
250 260 270 280 290 300
RHLEKLQQQQ IDIQTHFISA ALKTSSFQPV SMPSSRAVEK YSVKPEHPNL GSCNPSLYNT
310 320 330 340 350 360
FASKQAPLKE VEDTSFDKQK SPLETPAPRR FAPVPVSRDD ELSKRENLLE EKENMEVSCH
370 380 390 400 410 420
RGNVRLLEQI LNNNDSLTRK SESSNTTSLT RSKIGWTPEK TNRFPSCEEL ETTKVTMQKS
430 440 450 460 470 480
DDVLHDLGQK EKETNSMVQP KESLSMLKLP DLPQNSVKLQ TTNTTRSVLK DAEKILRGVQ
490 500 510 520 530 540
NNKKVLEENL EAIIRAKDGA AMYSLINALS TNREMSEKIR IRKTVDEWIK TISAEIQDEL
550 560 570 580 590 600
SRTDYEQKRF DQKNQRTKKG QNMTKDIRTN TQDKTVNKSV IPRKHSQKQI EEHFRNLPMR
610 620 630 640 650 660
GMPASSLQKE RKEGLLKATT VIQDEDYMLQ VYGKPVYQGH RSTLKKGPYL RFNSPSPKSR
670 680 690 700 710 720
PQRPKVIERV KGTKVKSIRT QTDFYATKPK KMDSKMKHSV PVLPHGDQQY LFSPSREMPT
730 740 750 760 770 780
FSGTLEGHLI PMAILLGQTQ SNSDTMPPAG VIVSKPHPVT VTTSIPPSSR KVETGVKKPN
790 800 810 820 830 840
IAIVEMKSEK KDPPQLTVQV LPSVDIDSIS NSSADVLSPL SSPKEASLPP VQTWIKTPEI
850 860 870 880 890 900
MKVDEEEVKF PGTNFDEIID VIQEEEKCDE IPDSEPILEF NRSVKADSTK YNGPPFPPVA
910 920 930 940 950 960
STFQPTADIL DKVIERKETL ENSLIQWVEQ EIMSRIISGL FPVQQQIAPS ISVSVSETSE
970 980 990 1000 1010 1020
PLTSDIVEGT SSGALQLFVD AGVPVNSNVI KHFVNEALAE TIAVMLGDRE AKKQGPVATG
1030 1040 1050 1060 1070 1080
VSGDASTNET YLPARVCTPL PTPQPTPPCS PSSPAKECVL VKTPDSSPCD SDHDMAFPVK
1090 1100 1110 1120 1130 1140
EICAEKGDDM PAIMLVNTPT VTPTTTPPPA AAVFTPTLSD ISIDKLKVSS PELPKPWGDG
1150 1160 1170 1180 1190 1200
DLPLEEENPN SPQEELHPRA IVMSVAKDEE PESMDFPAQP PPPEPVPFMP FPAGTKAPSP
1210 1220 1230 1240 1250 1260
SQMPGSDSST LESTLSVTVT ETETLDKPIS EGEILFSCGQ KLAPKILEDI GLYLTNLNDS
1270 1280 1290 1300 1310 1320
LSSTLHDAVE MEDDPPSEGQ VIRMSHKKFH ADAILSFAKQ NQESAVSQQA VYHSEDLENS
1330 1340 1350 1360 1370 1380
VGELSEGQRP QLTAAAENIL MGHSLYMQPP VTNTQSLDQQ CDPKPLSRQF DTVSGSIYED
1390 1400 1410 1420 1430 1440
SCASHGPMSL GELELEPNSK LVLPTTLLTA QENDVNLPVA AEDFSQYQLK QNQDVKQVEH
1450 1460 1470 1480 1490 1500
KPSQSYLRVR NKSDIAPSQQ QVSPGDMDRT QIELNPYLTC VFSGGKAVPL SASQMPPAKM
1510 1520 1530
SVMLPSVNLE DCSQSLSLST MQEDMESSGA DTF
10 20 30 40 50 60
MPVKRLREVV SQNHGDHLVL LKDELPCVPP ALSANKRLPV GTGTSLNGTS RGSSDLTSAR
70 80 90 100 110 120
NCYQPLLENP MVSESDFSKD VAVQVLPLDK IEENNKQKAN DIFISQYTMG QKDALRTVLK
130 140 150 160 170 180
QKAQSMPVFK EVKVHLLEDA GIEKDAVTQE TRISPSGIDS ATTVAAATAA AIATAAPLIK
190 200 210 220 230 240
VQSDLEAKVN SVTELLSKLQ ETDKHLQRVT EQQTSIQRKQ EKLHCHDHEK QMNVFMEQHI
250 260 270 280 290 300
RHLEKLQQQQ IDIQTHFISA ALKTSSFQPV SMPSSRAVEK YSVKPEHPNL GSCNPSLYNT
310 320 330 340 350 360
FASKQAPLKE VEDTSFDKQK SPLETPAPRR FAPVPVSRDD ELSKRENLLE EKENMEVSCH
370 380 390 400 410 420
RGNVRLLEQI LNNNDSLTRK SESSNTTSLT RSKIGWTPEK TNRFPSCEEL ETTKVTMQKS
430 440 450 460 470 480
DDVLHDLGQK EKETNSMVQP KESLSMLKLP DLPQNSVKLQ TTNTTRSVLK DAEKILRGVQ
490 500 510 520 530 540
NNKKVLEENL EAIIRAKDGA AMYSLINALS TNREMSEKIR IRKTVDEWIK TISAEIQDEL
550 560 570 580 590 600
SRTDYEQKRF DQKNQRTKKG QNMTKDIRTN TQDKTVNKSV IPRKHSQKQI EEHFRNLPMR
610 620 630 640 650 660
GMPASSLQKE RKEGLLKATT VIQDEDYMLQ VYGKPVYQGH RSTLKKGPYL RFNSPSPKSR
670 680 690 700 710 720
PQRPKVIERV KGTKVKSIRT QTDFYATKPK KMDSKMKHSV PVLPHGDQQY LFSPSREMPT
730 740 750 760 770 780
FSGTLEGHLI PMAILLGQTQ SNSDTMPPAG VIVSKPHPVT VTTSIPPSSR KVETGVKKPN
790 800 810 820 830 840
IAIVEMKSEK KDPPQLTVQV LPSVDIDSIS NSSADVLSPL SSPKEASLPP VQTWIKTPEI
850 860 870 880 890 900
MKVDEEEVKF PGTNFDEIID VIQEEEKCDE IPDSEPILEF NRSVKADSTK YNGPPFPPVA
910 920 930 940 950 960
STFQPTADIL DKVIERKETL ENSLIQWVEQ EIMSRIISGL FPVQQQIAPS ISVSVSETSE
970 980 990 1000 1010 1020
PLTSDIVEGT SSGALQLFVD AGVPVNSNVI KHFVNEALAE TIAVMLGDRE AKKQGPVATG
1030 1040 1050 1060 1070 1080
VSGDASTNET YLPARVCTPL PTPQPTPPCS PSSPAKECVL VKTPDSSPCD SDHDMAFPVK
1090 1100 1110 1120 1130 1140
EICAEKGDDM PAIMLVNTPT VTPTTTPPPA AAVFTPTLSD ISIDKLKVSS PELPKPWGDG
1150 1160 1170 1180 1190 1200
DLPLEEENPN SPQEELHPRA IVMSVAKDEE PESMDFPAQP PPPEPVPFMP FPAGTKAPSP
1210 1220 1230 1240 1250 1260
SQMPGSDSST LESTLSVTVT ETETLDKPIS EGEILFSCGQ KLAPKILEDI GLYLTNLNDS
1270 1280 1290 1300 1310 1320
LSSTLHDAVE MEDDPPSEGQ VIRMSHKKFH ADAILSFAKQ NQESAVSQQA VYHSEDLENS
1330 1340 1350 1360 1370 1380
VGELSEGQRP QLTAAAENIL MGHSLYMQPP VTNTQSLDQQ CDPKPLSRQF DTVSGSIYED
1390 1400 1410 1420 1430 1440
SCASHGPMSL GELELEPNSK LVLPTTLLTA QENDVNLPVA AEDFSQYQLK QNQDVKQVEH
1450 1460 1470 1480 1490 1500
KPSQSYLRVR NKSDIAPSQQ QVSPGDMDRT QIELNPYLTC VFSGGKAVPL SASQMPPAKM
1510 1520 1530
SVMLPSVNLE DCSQSLSLST MQEDMESSGA DTF
10 20 30 40 50 60
MPVKRLREVV SQNHGDHLVL LKDELPCVPP ALSANKRLPV GTGTSLNGTS RGSSDLTSAR
70 80 90 100 110 120
NCYQPLLENP MVSESDFSKD VAVQVLPLDK IEENNKQKAN DIFISQYTMG QKDALRTVLK
130 140 150 160 170 180
QKAQSMPVFK EVKVHLLEDA GIEKDAVTQE TRISPSGIDS ATTVAAATAA AIATAAPLIK
190 200 210 220 230 240
VQSDLEAKVN SVTELLSKLQ ETDKHLQRVT EQQTSIQRKQ EKLHCHDHEK QMNVFMEQHI
250 260 270 280 290 300
RHLEKLQQQQ IDIQTHFISA ALKTSSFQPV SMPSSRAVEK YSVKPEHPNL GSCNPSLYNT
310 320 330 340 350 360
FASKQAPLKE VEDTSFDKQK SPLETPAPRR FAPVPVSRDD ELSKRENLLE EKENMEVSCH
370 380 390 400 410 420
RGNVRLLEQI LNNNDSLTRK SESSNTTSLT RSKIGWTPEK TNRFPSCEEL ETTKVTMQKS
430 440 450 460 470 480
DDVLHDLGQK EKETNSMVQP KESLSMLKLP DLPQNSVKLQ TTNTTRSVLK DAEKILRGVQ
490 500 510 520 530 540
NNKKVLEENL EAIIRAKDGA AMYSLINALS TNREMSEKIR IRKTVDEWIK TISAEIQDEL
550 560 570 580 590 600
SRTDYEQKRF DQKNQRTKKG QNMTKDIRTN TQDKTVNKSV IPRKHSQKQI EEHFRNLPMR
610 620 630 640 650 660
GMPASSLQKE RKEGLLKATT VIQDEDYMLQ VYGKPVYQGH RSTLKKGPYL RFNSPSPKSR
670 680 690 700 710 720
PQRPKVIERV KGTKVKSIRT QTDFYATKPK KMDSKMKHSV PVLPHGDQQY LFSPSREMPT
730 740 750 760 770 780
FSGTLEGHLI PMAILLGQTQ SNSDTMPPAG VIVSKPHPVT VTTSIPPSSR KVETGVKKPN
790 800 810 820 830 840
IAIVEMKSEK KDPPQLTVQV LPSVDIDSIS NSSADVLSPL SSPKEASLPP VQTWIKTPEI
850 860 870 880 890 900
MKVDEEEVKF PGTNFDEIID VIQEEEKCDE IPDSEPILEF NRSVKADSTK YNGPPFPPVA
910 920 930 940 950 960
STFQPTADIL DKVIERKETL ENSLIQWVEQ EIMSRIISGL FPVQQQIAPS ISVSVSETSE
970 980 990 1000 1010 1020
PLTSDIVEGT SSGALQLFVD AGVPVNSNVI KHFVNEALAE TIAVMLGDRE AKKQGPVATG
1030 1040 1050 1060 1070 1080
VSGDASTNET YLPARVCTPL PTPQPTPPCS PSSPAKECVL VKTPDSSPCD SDHDMAFPVK
1090 1100 1110 1120 1130 1140
EICAEKGDDM PAIMLVNTPT VTPTTTPPPA AAVFTPTLSD ISIDKLKVSS PELPKPWGDG
1150 1160 1170 1180 1190 1200
DLPLEEENPN SPQEELHPRA IVMSVAKDEE PESMDFPAQP PPPEPVPFMP FPAGTKAPSP
1210 1220 1230 1240 1250 1260
SQMPGSDSST LESTLSVTVT ETETLDKPIS EGEILFSCGQ KLAPKILEDI GLYLTNLNDS
1270 1280 1290 1300 1310 1320
LSSTLHDAVE MEDDPPSEGQ VIRMSHKKFH ADAILSFAKQ NQESAVSQQA VYHSEDLENS
1330 1340 1350 1360 1370 1380
VGELSEGQRP QLTAAAENIL MGHSLYMQPP VTNTQSLDQQ CDPKPLSRQF DTVSGSIYED
1390 1400 1410 1420 1430 1440
SCASHGPMSL GELELEPNSK LVLPTTLLTA QENDVNLPVA AEDFSQYQLK QNQDVKQVEH
1450 1460 1470 1480 1490 1500
KPSQSYLRVR NKSDIAPSQQ QVSPGDMDRT QIELNPYLTC VFSGGKAVPL SASQMPPAKM
1510 1520 1530
SVMLPSVNLE DCSQSLSLST MQEDMESSGA DTF
Protein Neighborhood
Domains & Features
7 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9BVV6-1-unknown | MPVKRL... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9BVV6-1-unknown | MPVKRL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt106531 | |||
Q9BVV6-1-unknown | MPVKRL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt106530 | |||
Q9BVV6-71-unknown | MVSESD... | 71 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt91496 | |||
Q9BVV6-71-unknown | MVSESD... | 71 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt101835 | |||
Q9BVV6-71-unknown | MVSESD... | 71 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt101834 | |||
Q9BVV6-808-unknown | SISNSS... | 808 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt172882 | |||
Q9BVV6-808-unknown | SISNSS... | 808 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt172880 | |||
Q9BVV6-808-unknown | SISNSS... | 808 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt172881 | |||
Q9BVV6-808- | SISNSS... | 808 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9BVV6-1025-unknown | ASTNET... | 1025 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13231 | |||
Q9BVV6-1025-unknown | ASTNET... | 1025 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157076 | |||
Q9BVV6-1025-unknown | ASTNET... | 1025 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157146 | |||
Q9BVV6-1025-unknown | ASTNET... | 1025 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157357 | |||
Q9BVV6-1268- | AVEMED... | 1268 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q9BVV6-1268-unknown | AVEMED... | 1268 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176923 | |||
Q9BVV6-1268-unknown | AVEMED... | 1268 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176921 | |||
Q9BVV6-1268-unknown | AVEMED... | 1268 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176922 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...GVSGDA | 1024 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13231 | |||
...GVSGDA | 1024 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140574 | |||
...GVSGDA | 1024 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140646 | |||
...GVSGDA | 1024 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140856 | |||
...GADTF | 1533 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...GADTF | 1533 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt87112 | |||
...GADTF | 1533 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt87114 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 1024 | SGDA.|.ASTN | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|