Q9H8Y8: Golgi reassembly-stacking protein 2

General Information

Protein names	- Golgi reassembly-stacking protein 2 - GRS2 - Golgi phosphoprotein 6 - GOLPH6 - Golgi reassembly-stacking protein of 55 kDa - GRASP55 - p59
Gene names	GORASP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9H8Y8

4 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Golgi reassembly-stacking protein 2 - Isoform 3 of Golgi reassembly-stacking protein 2

Sequence View

        10         20         30         40         50         60
MGSSQSVEIP GGGTEGYHVL RVQENSPGHR AGLEPFFDFI VSINGSRLNK DNDTLKDLLK
        70         80         90        100        110        120
ANVEKPVKML IYSSKTLELR ETSVTPSNLW GGQGLLGVSI RFCSFDGANE NVWHVLEVES
       130        140        150        160        170        180
NSPAALAGLR PHSDYIIGAD TVMNESEDLF SLIETHEAKP LKLYVYNTDT DNCREVIITP
       190        200        210        220        230        240
NSAWGGEGSL GCGIGYGYLH RIPTRPFEEG KKISLPGQMA GTPITPLKDG FTEVQLSSVN
       250        260        270        280        290        300
PPSLSPPGTT GIEQSLTGLS ISSTPPAVSS VLSTGVPTVP LLPPQVNQSL TSVPPMNPAT
       310        320        330        340        350        360
TLPGLMPLPA GLPNLPNLNL NLPAPHIMPG VGLPELVNPG LPPLPSMPPR NLPGIAPLPL
       370        380        390        400        410        420
PSEFLPSFPL VPESSSAASS GELLSSLPPT SNAPSDPATT TAKADAASSL TVDVTPPTAK
       430        440        450
APTTVEDRVG DSTPVSEKPV SAAVDANASE SP         10         20         30         40         50         60
MGSSQSVEIP GGGTEGYHVL RVQENSPGHR AGLEPFFDFI VSINGSRLNK DNDTLKDLLK
        70         80         90        100        110        120
ANVEKPVKML IYSSKTLELR ETSVTPSNLW GGQGLLGVSI RFCSFDGANE NVWHVLEVES
       130        140        150        160        170        180
NSPAALAGLR PHSDYIIGAD TVMNESEDLF SLIETHEAKP LKLYVYNTDT DNCREVIITP
       190        200        210        220        230        240
NSAWGGEGSL GCGIGYGYLH RIPTRPFEEG KKISLPGQMA GTPITPLKDG FTEVQLSSVN
       250        260        270        280        290        300
PPSLSPPGTT GIEQSLTGLS ISSTPPAVSS VLSTGVPTVP LLPPQVNQSL TSVPPMNPAT
       310        320        330        340        350        360
TLPGLMPLPA GLPNLPNLNL NLPAPHIMPG VGLPELVNPG LPPLPSMPPR NLPGIAPLPL
       370        380        390        400        410        420
PSEFLPSFPL VPESSSAASS GELLSSLPPT SNAPSDPATT TAKADAASSL TVDVTPPTAK
       430        440        450
APTTVEDRVG DSTPVSEKPV SAAVDANASE SP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9H8Y8-2-unknown	GSSQSV...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9H8Y8-69-unknown	MLIYSS...	69	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt76223
Q9H8Y8-69-unknown	MLIYSS...	69	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106549
Q9H8Y8-386-unknown	SLPPTS...	386		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9H8Y8-386-unknown	SLPPTS...	386	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161609
Q9H8Y8-386-unknown	SLPPTS...	386	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161608
Q9H8Y8-386-	SLPPTS...	386		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9H8Y8-386-	SLPPTS...	386		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q9H8Y8-386-	SLPPTS...	386		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
Q9H8Y8-386-	SLPPTS...	386		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q9H8Y8-386-	SLPPTS...	386		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...AVDANA	447	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13341
...AVDANA	447	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt135009
...AVDANA	447	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt136334
...ASESP	452		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...ASESP	452	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...ASESP	452	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt71841
...ASESP	452	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt71842
...ASESP	452		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	447	DANA.\|.ASES	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)