Q96S55: ATPase WRNIP1

General Information

Protein names	- ATPase WRNIP1 - 3.6.1.3 {ECO:0000269\|PubMed:15670210} - Werner helicase-interacting protein 1
Gene names	WRNIP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96S55

6 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of ATPase WRNIP1 - Isoform 3 of ATPase WRNIP1 - Isoform 4 of ATPase WRNIP1

Sequence View

        10         20         30         40         50         60
MEVSGPEDDP FLSQLHQVQC PVCQQMMPAA HINSHLDRCL LLHPAGHAEP AAGSHRAGER
        70         80         90        100        110        120
AKGPSPPGAK RRRLSESSAL KQPATPTAAE SSEGEGEEGD DGGETESRES YDAPPTPSGA
       130        140        150        160        170        180
RLIPDFPVAR SSSPGRKGSG KRPAAAAAAG SASPRSWDEA EAQEEEEAVG DGDGDGDADA
       190        200        210        220        230        240
DGEDDPGHWD ADAAEAATAF GASGGGRPHP RALAAEEIRQ MLQGKPLADT MRPDTLQDYF
       250        260        270        280        290        300
GQSKAVGQDT LLRSLLETNE IPSLILWGPP GCGKTTLAHI IASNSKKHSI RFVTLSATNA
       310        320        330        340        350        360
KTNDVRDVIK QAQNEKSFFK RKTILFIDEI HRFNKSQQDT FLPHVECGTI TLIGATTENP
       370        380        390        400        410        420
SFQVNAALLS RCRVIVLEKL PVEAMVTILM RAINSLGIHV LDSSRPTDPL SHSSNSSSEP
       430        440        450        460        470        480
AMFIEDKAVD TLAYLSDGDA RAGLNGLQLA VLARLSSRKM FCKKSGQSYS PSRVLITEND
       490        500        510        520        530        540
VKEGLQRSHI LYDRAGEEHY NCISALHKSM RGSDQNASLY WLARMLEGGE DPLYVARRLV
       550        560        570        580        590        600
RFASEDIGLA DPSALTQAVA AYQGCHFIGM PECEVLLAQC VVYFARAPKS IEVYSAYNNV
       610        620        630        640        650        660
KACLRNHQGP LPPVPLHLRN APTRLMKDLG YGKGYKYNPM YSEPVDQEYL PEELRGVDFF

KQRRC         10         20         30         40         50         60
MEVSGPEDDP FLSQLHQVQC PVCQQMMPAA HINSHLDRCL LLHPAGHAEP AAGSHRAGER
        70         80         90        100        110        120
AKGPSPPGAK RRRLSESSAL KQPATPTAAE SSEGEGEEGD DGGETESRES YDAPPTPSGA
       130        140        150        160        170        180
RLIPDFPVAR SSSPGRKGSG KRPAAAAAAG SASPRSWDEA EAQEEEEAVG DGDGDGDADA
       190        200        210        220        230        240
DGEDDPGHWD ADAAEAATAF GASGGGRPHP RALAAEEIRQ MLQGKPLADT MRPDTLQDYF
       250        260        270        280        290        300
GQSKAVGQDT LLRSLLETNE IPSLILWGPP GCGKTTLAHI IASNSKKHSI RFVTLSATNA
       310        320        330        340        350        360
KTNDVRDVIK QAQNEKSFFK RKTILFIDEI HRFNKSQQDT FLPHVECGTI TLIGATTENP
       370        380        390        400        410        420
SFQVNAALLS RCRVIVLEKL PVEAMVTILM RAINSLGIHV LDSSRPTDPL SHSSNSSSEP
       430        440        450        460        470        480
AMFIEDKAVD TLAYLSDGDA RAGLNGLQLA VLARLSSRKM FCKKSGQSYS PSRVLITEND
       490        500        510        520        530        540
VKEGLQRSHI LYDRAGEEHY NCISALHKSM RGSDQNASLY WLARMLEGGE DPLYVARRLV
       550        560        570        580        590        600
RFASEDIGLA DPSALTQAVA AYQGCHFIGM PECEVLLAQC VVYFARAPKS IEVYSAYNNV
       610        620        630        640        650        660
KACLRNHQGP LPPVPLHLRN APTRLMKDLG YGKGYKYNPM YSEPVDQEYL PEELRGVDFF

KQRRC         10         20         30         40         50         60
MEVSGPEDDP FLSQLHQVQC PVCQQMMPAA HINSHLDRCL LLHPAGHAEP AAGSHRAGER
        70         80         90        100        110        120
AKGPSPPGAK RRRLSESSAL KQPATPTAAE SSEGEGEEGD DGGETESRES YDAPPTPSGA
       130        140        150        160        170        180
RLIPDFPVAR SSSPGRKGSG KRPAAAAAAG SASPRSWDEA EAQEEEEAVG DGDGDGDADA
       190        200        210        220        230        240
DGEDDPGHWD ADAAEAATAF GASGGGRPHP RALAAEEIRQ MLQGKPLADT MRPDTLQDYF
       250        260        270        280        290        300
GQSKAVGQDT LLRSLLETNE IPSLILWGPP GCGKTTLAHI IASNSKKHSI RFVTLSATNA
       310        320        330        340        350        360
KTNDVRDVIK QAQNEKSFFK RKTILFIDEI HRFNKSQQDT FLPHVECGTI TLIGATTENP
       370        380        390        400        410        420
SFQVNAALLS RCRVIVLEKL PVEAMVTILM RAINSLGIHV LDSSRPTDPL SHSSNSSSEP
       430        440        450        460        470        480
AMFIEDKAVD TLAYLSDGDA RAGLNGLQLA VLARLSSRKM FCKKSGQSYS PSRVLITEND
       490        500        510        520        530        540
VKEGLQRSHI LYDRAGEEHY NCISALHKSM RGSDQNASLY WLARMLEGGE DPLYVARRLV
       550        560        570        580        590        600
RFASEDIGLA DPSALTQAVA AYQGCHFIGM PECEVLLAQC VVYFARAPKS IEVYSAYNNV
       610        620        630        640        650        660
KACLRNHQGP LPPVPLHLRN APTRLMKDLG YGKGYKYNPM YSEPVDQEYL PEELRGVDFF

KQRRC

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96S55-1-unknown	MEVSGP...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96S55-1-unknown	MEVSGP...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94622
Q96S55-221-unknown	MLQGKP...	221	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94623
Q96S55-221-unknown	MLQGKP...	221	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt104779
Q96S55-235-unknown	TLQDYF...	235	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13114
Q96S55-235-unknown	TLQDYF...	235	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136535
Q96S55-235-unknown	TLQDYF...	235	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147919
Q96S55-385-unknown	MVTILM...	385	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94624
Q96S55-385-unknown	MVTILM...	385	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt104828
Q96S55-385-unknown	MVTILM...	385	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt104829
Q96S55-416-	SSSEPA...	416		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q96S55-416-unknown	SSSEPA...	416	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171836
Q96S55-416-unknown	SSSEPA...	416	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171837
Q96S55-416-unknown	SSSEPA...	416	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171838

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TMRPDT	234	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13114
...TMRPDT	234	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131279
...KQRRC	665	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KQRRC	665	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt90242
...KQRRC	665	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt90241
...KQRRC	665	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt90240

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	234	RPDT.\|.TLQD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)