P17480: Nucleolar transcription factor 1

General Information

Protein names	- Nucleolar transcription factor 1 - Autoantigen NOR-90 - Upstream-binding factor 1 - UBF-1
Gene names	UBTF
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P17480

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNGEADCPTD LEMAAPKGQD RWSQEDMLTL LECMKNNLPS NDSSKFKTTE SHMDWEKVAF
        70         80         90        100        110        120
KDFSGDMCKL KWVEISNEVR KFRTLTELIL DAQEHVKNPY KGKKLKKHPD FPKKPLTPYF
       130        140        150        160        170        180
RFFMEKRAKY AKLHPEMSNL DLTKILSKKY KELPEKKKMK YIQDFQREKQ EFERNLARFR
       190        200        210        220        230        240
EDHPDLIQNA KKSDIPEKPK TPQQLWYTHE KKVYLKVRPD ATTKEVKDSL GKQWSQLSDK
       250        260        270        280        290        300
KRLKWIHKAL EQRKEYEEIM RDYIQKHPEL NISEEGITKS TLTKAERQLK DKFDGRPTKP
       310        320        330        340        350        360
PPNSYSLYCA ELMANMKDVP STERMVLCSQ QWKLLSQKEK DAYHKKCDQK KKDYEVELLR
       370        380        390        400        410        420
FLESLPEEEQ QRVLGEEKML NINKKQATSP ASKKPAQEGG KGGSEKPKRP VSAMFIFSEE
       430        440        450        460        470        480
KRRQLQEERP ELSESELTRL LARMWNDLSE KKKAKYKARE AALKAQSERK PGGEREERGK
       490        500        510        520        530        540
LPESPKRAEE IWQQSVIGDY LARFKNDRVK ALKAMEMTWN NMEKKEKLMW IKKAAEDQKR
       550        560        570        580        590        600
YERELSEMRA PPAATNSSKK MKFQGEPKKP PMNGYQKFSQ ELLSNGELNH LPLKERMVEI
       610        620        630        640        650        660
GSRWQRISQS QKEHYKKLAE EQQKQYKVHL DLWVKSLSPQ DRAAYKEYIS NKRKSMTKLR
       670        680        690        700        710        720
GPNPKSSRTT LQSKSESEED DEEDEDDEDE DEEEEDDENG DSSEDGGDSS ESSSEDESED
       730        740        750        760
GDENEEDDED EDDDEDDDED EDNESEGSSS SSSSSGDSSD SDSN

Isoforms

- Isoform UBF2 of Nucleolar transcription factor 1

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P17480-1-unknown	MNGEAD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93618
P17480-1-Acetylation	MNGEAD...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P17480-1-Acetylation	MNGEAD...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P17480-1-Acetylation	MNGEAD...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P17480-1-Acetylation	MNGEAD...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt103763
P17480-221-unknown	ATTKEV...	221		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11261

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KVRPDA	220	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11261
...KVRPDA	220	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155819
...DSDSN	764	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DSDSN	764	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89236

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	220	RPDA.\|.ATTK	inferred from experiment	unknown	MEROPS	Rosen A	Casciola-Rosen L et al.:Cleavage by granzyme B is stron... (S01.010)	10499920,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)